Results 41 to 50 of about 932,523 (265)

Periferik Sinirlerin Histomorfometrik Analizinde TT-MMS Programının Güvenilirliğinin Karşılaştırmalı Olarak İncelenmesi

Uludağ Üniversitesi Tıp Fakültesi Dergisi, 2022
Deneysel çalışmalarda periferik sinirin akson çapı, miyelinli sinir lifi çapı ve miyelinli sinir için iç çap/dış çap oranı (g-ratio), demiyelinizasyon, remiyelinizasyon ve sinir onarımının değerlendirilmesinde görüntü analiz programlarından ...
Pınar Ayran Fidan
doaj   +1 more source

Importin 13-dependent Axon Diameter Growth Regulates Conduction Speeds along Myelinated CNS Axons

Nature Communications, 2023
Summary Central nervous system neurons have axons that vary over 100-fold in diameter. This diversity contributes to the regulation of myelination and conduction velocity along axons, which is critical for proper nervous system function.
Bin JM, Suminaite D, Benito-Kwiecinski SK, Kegel L, Rubio-Brotons M, Early JJ, Soong D, Livesey MR, Poole RJ, Lyons DA.   +9 more
europepmc   +7 more sources

Axon radius measurements in vivo from diffusion MRI: A feasibility study [PDF]

, 2007
This paper investigates the feasibility of using diffusion MRI to measure axon-cell dimensions in the white matter of live subjects. A simple geometric model of white-matter tissue provides an expression that relates the axon radius to the diffusion MRI ...
Daniel C. Alexander, Alexander, DC
core   +1 more source

Axon Diameter Measurements using Diffusion MRI are Infeasible [PDF]

, 2020
Abstract The feasibility of non-invasive axonal diameter quantification with diffusion MRI is a strongly debated topic due to the neuroscientific potential of such information and its relevance for the axonal signal transmission speed. It has been shown that under ideal conditions, the minimal diameter producing detectable signal decay ...
Michael Paquette, Cornelius Eichner, Thomas R. Knösche, Alfred Anwander   +3 more
openaire   +2 more sources

A simple and robust method for automating analysis of naïve and regenerating peripheral nerves.

PLoS ONE, 2021
BackgroundManual axon histomorphometry (AH) is time- and resource-intensive, which has inspired many attempts at automation. However, there has been little investigation on implementation of automated programs for widespread use.
Alison L Wong, Nicholas Hricz, Harsha Malapati, Nicholas von Guionneau, Michael Wong, Thomas Harris, Mathieu Boudreau, Julien Cohen-Adad, Sami Tuffaha   +8 more
doaj   +1 more source

Neuronal deletion of GSK3beta increases microtubule speed in the growth cone and enhances axon regeneration via CRMP-2 and independently of MAP1B and CLASP2 [PDF]

, 2014
BackgroundIn the adult central nervous system, axonal regeneration is abortive. Regulators of microtubule dynamics have emerged as attractive targets to promote axonal growth following injury as microtubule organization is pivotal for growth cone ...
Sílvia Vieira, Wittmann, Torsten, Sousa, Mónica M., Márcia A Liz, Pimentel, Helena I., Vera F Sousa, Telma E Santos, Vieira, Sílvia, Marques, Ana M., Sutherland, Calum; id_orcid, Hayley Pemble, Liz, Márcia A., Calum Sutherland, Mar, Fernando M., Mónica M Sousa, Pemble, Hayley, Sousa, Vera F., Helena I Pimentel, James R Woodgett, Morgado, Marlene M., Torsten Wittmann, Woodgett, James R., Santos, Telma E., Fernando M Mar, Ana M Marques, Marlene M Morgado   +25 more
core   +1 more source

Nerve impulse blockage in squid axons by n‐alkanes: the effect of axon diameter.

The Journal of Physiology, 1982
1. The anaesthetic effects of aqueous solutions of the n‐alkanes pentane to nonane on the propagated action potential of squid axons have been investigated for a range of axon diameters. 2. By the use of small axons (approx. 200 microns diameter) to minimize effects due to long diffusion times and alkane depletion it was found that n‐pentane and n ...
Haydon, D A, Hendry, B M
openaire   +3 more sources

The Diameter of Cortical Axons Depends Both on the Area of Origin and Target [PDF]

Cerebral Cortex, 2013
In primates, different cortical areas send axons of different diameters into comparable tracts, notably the corpus callosum (Tomasi S, Caminiti R, Innocenti GM. 2012. Areal differences in diameter and length of corticofugal projections. Cereb Cortex. 22:1463-1472). We now explored if an area also sends axons of different diameters to different targets.
Innocenti GM, VERCELLI, Alessandro, Caminiti R.   +2 more
openaire   +3 more sources

Noninvasive quantification of axon radii using diffusion MRI

eLife, 2020
Axon caliber plays a crucial role in determining conduction velocity and, consequently, in the timing and synchronization of neural activation. Noninvasive measurement of axon radii could have significant impact on the understanding of healthy and ...
Jelle Veraart, Daniel Nunes, Umesh Rudrapatna, Els Fieremans, Derek K Jones, Dmitry S Novikov, Noam Shemesh   +6 more
doaj   +1 more source

Developmental axon diameter growth of central nervous system axons does not depend on ensheathment or myelination by oligodendrocytes

SUMMARY Myelination facilitates the rapid conduction of action potentials along axons. In the central nervous system (CNS), myelinated axons vary over 100-fold in diameter, with conduction speed scaling linearly with increasing diameter.
Bin JM, Emberley K, Buscham TJ, Eichel-Vogel MA, Doan RA, Steyer AM, Nolan MF, Möbius W, Monk KR, Werner HB, Emery B, Lyons DA.   +11 more
europepmc   +2 more sources