Results 31 to 40 of about 932,523 (265)

Boosting neuregulin 1 type-III expression hastens SMA motor axon maturation

Acta Neuropathologica Communications, 2023
Intercellular communication between axons and Schwann cells is critical for attaining the complex morphological steps necessary for axon maturation.
Lingling Kong, Cera W. Hassinan, Florian Gerstner, Jannik M. Buettner, Jeffrey B. Petigrow, David O. Valdivia, Michelle H. Chan-Cortés, Amy Mistri, Annie Cao, Scott Alan McGaugh, Madeline Denton, Stephen Brown, Joshua Ross, Markus H. Schwab, Christian M. Simon, Charlotte J. Sumner   +15 more
doaj   +1 more source

Differential impacts of Cntnap2 heterozygosity and Cntnap2 null homozygosity on axon and myelinated fiber development in mouse

Frontiers in Neuroscience, 2023
Over the last decade, a large variety of alterations of the Contactin Associated Protein 2 (CNTNAP2) gene, encoding Caspr2, have been identified in several neuronal disorders, including neurodevelopmental disorders and peripheral neuropathies.
Carmen Cifuentes-Diaz, Carmen Cifuentes-Diaz, Carmen Cifuentes-Diaz, Giorgia Canali, Giorgia Canali, Giorgia Canali, Marta Garcia, Marta Garcia, Marta Garcia, Mélanie Druart, Mélanie Druart, Mélanie Druart, Taylor Manett, Taylor Manett, Taylor Manett, Mythili Savariradjane, Mythili Savariradjane, Mythili Savariradjane, Camille Guillaume, Camille Guillaume, Camille Guillaume, Corentin Le Magueresse, Corentin Le Magueresse, Corentin Le Magueresse, Laurence Goutebroze, Laurence Goutebroze, Laurence Goutebroze   +26 more
doaj   +1 more source

Mapping the human connectome using diffusion MRI at 300 mT/m gradient strength: Methodological advances and scientific impact

NeuroImage, 2022
Tremendous efforts have been made in the last decade to advance cutting-edge MRI technology in pursuit of mapping structural connectivity in the living human brain with unprecedented sensitivity and speed. The first Connectom 3T MRI scanner equipped with
Qiuyun Fan, Cornelius Eichner, Maryam Afzali, Lars Mueller, Chantal M.W. Tax, Mathias Davids, Mirsad Mahmutovic, Boris Keil, Berkin Bilgic, Kawin Setsompop, Hong-Hsi Lee, Qiyuan Tian, Chiara Maffei, Gabriel Ramos-Llordén, Aapo Nummenmaa, Thomas Witzel, Anastasia Yendiki, Yi-Qiao Song, Chu-Chung Huang, Ching-Po Lin, Nikolaus Weiskopf, Alfred Anwander, Derek K. Jones, Bruce R. Rosen, Lawrence L. Wald, Susie Y. Huang   +25 more
doaj   +1 more source

Microstructural parameter estimation in vivo using diffusion MRI and structured prior information. [PDF]

, 2016
Diffusion MRI has recently been used with detailed models to probe tissue microstructure. Much of this work has been performed ex vivo with powerful scanner hardware, to gain sensitivity to parameters such as axon radius.
Weiskopf, N, Weiskopf, N. ; https://orcid.org/, Zoltan Nagy, Chris A. Clark, Clark, CA, Clayden, JD, Alexander, DC, Nikolaus Weiskopf, Nagy, Z, Alexander, D., Nagy, Z., Clark, C., Jonathan D. Clayden, Daniel C. Alexander, Clayden, J.   +14 more
core   +1 more source

Interplay between MRI-based axon diameter and myelination estimates in macaque and human brain. [PDF]

Imaging Neurosci (Camb)
Axon diameter and myelin thickness are closely related microstructural tissue properties that affect the conduction velocity of action potentials in the nervous system.
Gong T, Maffei C, Dann E, Lee HH, Lee H, Augustinack JC, Huang SY, Haber SN, Yendiki A.   +8 more
europepmc   +3 more sources

Commissural Axon Kinetics and the Role of Netrin in Early Brain Circuitry Development [PDF]

, 2005
As neurons begin to differentiate, they send out processes called axons to initiate the formation of functional nerve connections. A specialized structure at the end of an axon called the growth cone is believed to possess the impressive navigational and
Bak-Maier, Magdalena
core   +1 more source

Axon Diameter Mapping From Myelin Water Diffusion MRI. [PDF]

IEEE Trans Med Imaging
Probing diffusion in myelin water using diffusion-weighted T1-/T2-selective MRI acquisitions enables noninvasive measurement of myelinated axon diameter. Its application for in vivo measurements requires numerical verification through diffusion simulations.
Lee HH, Chan KS, Novikov DS, Fieremans E, Huang SY.   +4 more
europepmc   +3 more sources

Axon Diameter Mapping in Crossing Fibers with Diffusion MRI [PDF]

, 2011
This paper proposes a technique for a previously unaddressed problem, namely, mapping axon diameter in crossing fiber regions, using diffusion MRI. Direct measurement of tissue microstructure of this kind using diffusion MRI offers a new class of biomarkers that give more specific information about tissue than measures derived from diffusion tensor ...
Hui Zhang 0005, Tim B. Dyrby, Daniel C. Alexander   +2 more
openaire   +3 more sources

PGSE, OGSE, and sensitivity to axon diameter in diffusion MRI: Insight from a simulation study [PDF]

Magnetic Resonance in Medicine, 2016
Enrico Kaden, Andrada Ianuş, Ivana Drobnjak   +2 more
exaly   +2 more sources

Development of the early axon scaffold in the rostral brain of the small spotted cat shark (Scyliorhinus canicula) embryo [PDF]

, 2014
International audienceThe cat shark is increasingly used as a model for Chondrichthyes, an evolutionarily important sister group of the bony vertebrates that include teleosts and tetrapods.
Waring, Colin P., Schubert, Frank, Waring, Colin, Schubert, Frank R., Ware, Michelle   +4 more
core   +1 more source