Results 21 to 30 of about 932,523 (265)

Revisiting the interpretation of axon diameter mapping using higher-order signal representations. [PDF]

open access: yesImaging Neurosci (Camb)
Diffusion-weighted Magnetic Resonance Imaging (dMRI) has emerged as an imaging modality of interest to measure axon diameters noninvasively. The previously observed b-½ power law scaling suggests that high b-value dMRI signals originate from water ...
Karat BG   +6 more
europepmc   +2 more sources

Scan-rescan repeatability of axonal imaging metrics using high-gradient diffusion MRI and statistical implications for study design

open access: yesNeuroImage, 2021
Axon diameter mapping using diffusion MRI in the living human brain has attracted growing interests with the increasing availability of high gradient strength MRI systems.
Qiuyun Fan   +7 more
doaj   +1 more source

Experience-related reductions of myelin and axon diameter in adulthood. [PDF]

open access: yesJ Neurophysiol, 2018
The production of new myelin has been highlighted as an underappreciated mechanism of brain plasticity, but whether plastic decreases in myelin also happen in the adult brain has been largely unexplored. Recently, Sinclair et al. (Sinclair JS, Fischl MJ, Alexandrova O, Heß M, Grothe B, Leibold C, and Kopp-Scheinpflug C. J Neurosci 37: 8239–8255, 2017)
Lazari A   +2 more
europepmc   +4 more sources

Evidence That ITPR2-Mediated Intracellular Calcium Release in Oligodendrocytes Regulates the Development of Carbonic Anhydrase II + Type I/II Oligodendrocytes and the Sizes of Myelin Fibers

open access: yesFrontiers in Cellular Neuroscience, 2021
Myelination of neuronal axons in the central nervous system (CNS) by oligodendrocytes (OLs) enables rapid saltatory conductance and axonal integrity, which are crucial for normal brain functioning.
Ruyi Mei   +14 more
doaj   +1 more source

Axon diameter and intra-axonal volume fraction of the corticospinal tract in idiopathic normal pressure hydrocephalus measured by q-space imaging. [PDF]

open access: yesPLoS ONE, 2014
PURPOSE: Previous studies suggest that compression and stretching of the corticospinal tract (CST) potentially cause treatable gait disturbance in patients with idiopathic normal pressure hydrocephalus (iNPH).
Kouhei Kamiya   +9 more
doaj   +1 more source

The influence of axonal beading and undulation on axonal diameter mapping

open access: yes, 2023
Abstract We consider the effect of non-cylindrical axonal shape on axonal diameter mapping with diffusion MRI. Practical sensitivity to axon diameter is attained at strong diffusion weightings b , where the deviation from the
Hong-Hsi Lee   +8 more
openaire   +2 more sources

Automated pipeline for nerve fiber selection and g-ratio calculation in optical microscopy: exploring staining protocol variations

open access: yesFrontiers in Neuroanatomy, 2023
G-ratio is crucial for understanding the nervous system’s health and function as it measures the relative myelin thickness around an axon. However, manual measurement is biased and variable, emphasizing the need for an automated and standardized ...
Bart R. Thomson   +5 more
doaj   +1 more source

Does powder averaging remove dispersion bias in diffusion MRI diameter estimates within real 3D axonal architectures?

open access: yesNeuroImage, 2022
Noninvasive estimation of axon diameter with diffusion MRI holds the potential to investigate the dynamic properties of the brain network and pathology of neurodegenerative diseases. Recent studies use powder averaging to account for complex white matter
Mariam Andersson   +5 more
doaj   +1 more source

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