Results 51 to 60 of about 932,523 (265)
The Mechanical Microenvironment Regulates Axon Diameters Visualized by Cryo-Electron Tomography
Cells, 2022 Axonal varicosities or swellings are enlarged structures along axon shafts and profoundly affect action potential propagation and synaptic transmission.
Di Ma +4 more
doaj +1 more source
Subunit composition of neurofilaments specifies axonal diameter. [PDF]
The Journal of cell biology, 1996 Neurofilaments (NFs), which are composed of NF-L, NF-M, and NF-H, are required for the development of normal axonal caliber, a property that in turn is a critical determinant of axonal conduction velocity. To investigate how each subunit contributes to the radial growth of axons, we used transgenic mice to alter the subunit composition of NFs ...
Z, Xu +8 more
openaire +2 more sources
Assessing the Feasibility of Estimating Axon Diameter using Diffusion Models and Machine Learning [PDF]
, 2017 Axon diameter estimation has been a focus of the diffusion MRI community for the past decade. The main argument has been that while diffusion models always overestimate the true axon diameter, their estimation still correlates with changes in true value.
Sepasian, N +4 more
core +5 more sources
Axon counts and diameter in various groups.
, 2019 Axon counts and diameter in various groups.
Jason Sheehan (735466) +4 more
core +1 more source
Rapid, automated nerve histomorphometry through open-source artificial intelligence
Scientific Reports, 2022 We aimed to develop and validate a deep learning model for automated segmentation and histomorphometry of myelinated peripheral nerve fibers from light microscopic images. A convolutional neural network integrated in the AxonDeepSeg framework was trained
Simeon Christian Daeschler +7 more
doaj +1 more source
Histology-informed automatic parcellation of white matter tracts in the rat spinal cord
Frontiers in Neuroanatomy, 2022 The white matter is organized into “tracts” or “bundles,” which connect different parts of the central nervous system. Knowing where these tracts are located in each individual is important for understanding the cause of potential sensorial, motor or ...
Harris Nami +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
eLife, 2022 Conduction velocity is the speed at which electrical signals travel along axons and is a crucial determinant of neural communication. Inferences about conduction velocity can now be made in vivo in humans using a measure called the magnetic resonance (MR)
Ian A Clark +3 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To determine whether integration of serum neurofilament light chain (NfL) and cortical dysfunction improves diagnostic accuracy in amyotrophic lateral sclerosis (ALS) when applied alongside the Gold Coast criteria (GCC). Methods In this prospective study, 148 participants with suspected ALS were recruited (101 ALS and 47 with ALS ...
Aicee Dawn Calma +16 more
wiley +1 more source
Quantitative analysis of mouse corpus callosum from electron microscopy images
Data in Brief, 2015 This article provides morphometric analysis of 72 electron microscopy images from control (n=4) and hypomyelinated (n=2) mouse corpus callosum. Measures of axon diameter and g-ratio were tabulated across all brains from two regions of the corpus callosum
Kathryn L. West +3 more
doaj +1 more source