Results 1 to 10 of about 102,974 (302)
Axon Guidance Molecules and Pain [PDF]
Cells, 2022 Chronic pain is a debilitating condition that influences the social, economic, and psychological aspects of patients’ lives. Hence, the need for better treatment is drawing extensive interest from the research community.
Elisa Damo, Manuela Simonetti
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Transcriptional control in embryonic Drosophila midline guidance assessed through a whole genome approach [PDF]
BMC Neuroscience, 2007 Background During the development of the Drosophila central nervous system the process of midline crossing is orchestrated by a number of guidance receptors and ligands.
Tomancak Pavel +3 more
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microRNAs in axon guidance [PDF]
Frontiers in Cellular Neuroscience, 2014 Brain wiring is a highly intricate process in which trillions of neuronal connections are established. Its initial phase is particularly crucial in establishing the general framework of neuronal circuits.
Archana N Iyer +2 more
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Where does axon guidance lead us? [version 1; referees: 2 approved] [PDF]
F1000Research, 2017 During neural circuit formation, axons need to navigate to their target cells in a complex, constantly changing environment. Although we most likely have identified most axon guidance cues and their receptors, we still cannot explain the molecular ...
Esther Stoeckli
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Exosomes: new targets for understanding axon guidance in the developing central nervous system [PDF]
Frontiers in Cell and Developmental BiologyAxon guidance is a key event in neural circuit development that drives the correct targeting of axons to their targets through long distances and unique patterns.
Mingyu Liu +4 more
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The role of axon guidance molecules in the pathogenesis of epilepsy [PDF]
Neural Regeneration ResearchCurrent treatments for epilepsy can only manage the symptoms of the condition but cannot alter the initial onset or halt the progression of the disease. Consequently, it is crucial to identify drugs that can target novel cellular and molecular mechanisms
Zheng Liu, Chunhua Pan, Hao Huang
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Commissural axon guidance in the developing spinal cord: from Cajal to the present day [PDF]
Neural Development, 2019 During neuronal development, the formation of neural circuits requires developing axons to traverse a diverse cellular and molecular environment to establish synaptic contacts with the appropriate postsynaptic partners.
J. D. Comer +3 more
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Frontiers in Neuroanatomy, 2021 Axon guidance proteins play key roles in the formation of neural circuits during development. We previously identified an axon guidance cue, named draxin, that has no homology with other axon guidance proteins.
Giasuddin Ahmed, Yohei Shinmyo
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Endoglycan plays a role in axon guidance by modulating cell adhesion
eLife, 2021 Axon navigation depends on the interactions between guidance molecules along the trajectory and specific receptors on the growth cone. However, our in vitro and in vivo studies on the role of Endoglycan demonstrate that in addition to specific guidance ...
Thomas Baeriswyl +11 more
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Glycosylation in Axonal Guidance [PDF]
International Journal of Molecular Sciences, 2021 How millions of axons navigate accurately toward synaptic targets during development is a long-standing question. Over decades, multiple studies have enriched our understanding of axonal pathfinding with discoveries of guidance molecules and morphogens, their receptors, and downstream signalling mechanisms.
Sampada P. Mutalik, Stephanie L. Gupton
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