Results 21 to 30 of about 966,766 (378)
Cbln1 regulates axon growth and guidance in multiple neural regions.
PLoS Biology, 2022 The accurate construction of neural circuits requires the precise control of axon growth and guidance, which is regulated by multiple growth and guidance cues during early nervous system development.
Peng Han +9 more
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Scientific Reports, 2020 Intra-retinal axon guidance involves a coordinated expression of transcription factors, axon guidance genes, and secretory molecules within the retina.
Soundararajan Lalitha +9 more
semanticscholar +1 more source
SYD-1C, UNC-40 (DCC) and SAX-3 (Robo) function interdependently to promote axon guidance by regulating the MIG-2 GTPase. [PDF]
PLoS Genetics, 2015 During development, axons must integrate directional information encoded by multiple guidance cues and their receptors. Axon guidance receptors, such as UNC-40 (DCC) and SAX-3 (Robo), can function individually or combinatorially with other guidance ...
Yan Xu +3 more
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Expression of Genes Involved in Axon Guidance: How Much Have We Learned?
International Journal of Molecular Sciences, 2020 Neuronal axons are guided to their target during the development of the brain. Axon guidance allows the formation of intricate neural circuits that control the function of the brain, and thus the behavior.
Sung Wook Kim, Kyong-Tai Kim
semanticscholar +1 more source
The midline protein regulates axon guidance by blocking the reiteration of neuroblast rows within the Drosophila ventral nerve cord. [PDF]
PLoS Genetics, 2013 Guiding axon growth cones towards their targets is a fundamental process that occurs in a developing nervous system. Several major signaling systems are involved in axon-guidance, and disruption of these systems causes axon-guidance defects. However, the
Mary Ann Manavalan +2 more
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SnapShot: Axon Guidance II [PDF]
Cell, 2013 BMP SE Repulsion BMP-RIB, BMP-RII - -COFILIN, LIMK1, PI3K, SMAD1, SMAD6DRAXIN SE Repulsion DCC - - -EPHRINA GPI Repulsion EPHA ADAM10 -a2-CHIMAERIN, EPHEXIN-1, NCK1/2, RAC1, RHOA, SPAR, VAV2/3EPHRINB TM Repulsion EPHB MMP2/9 -NCK1, PAK, p120GAP, RHOA, ROCK, VAV2/3EPHATM Repulsion EPHRINA ADAM10 P75 FYNAttraction EPHRINA - RET -EPHB TM Repulsion EPHRINB
R. Jeroen Pasterkamp, Alex L. Kolodkin
openaire +2 more sources
BMC Neuroscience, 2007 Background During the development of the Drosophila central nervous system the process of midline crossing is orchestrated by a number of guidance receptors and ligands.
Tomancak Pavel +3 more
doaj +1 more source
G3: Genes, Genomes, Genetics, 2018 During development, neuronal cells extend an axon toward their target destination in response to a cue to form a properly functioning nervous system.
Jamie K. Alan +4 more
doaj +1 more source
Drosophila semaphorin2b is Required for the Axon Guidance of a Subset of Embryonic Neurons [PDF]
, 2014 Background: The process of axon guidance is important in establishing functional neural circuits. The differential expression of cell-autonomous axon guidance factors is crucial for allowing axons of different neurons to take unique trajectories in ...
Emerson, Mark M +2 more
core +1 more source
The m6A reader YTHDF1 regulates axon guidance through translational control of Robo3.1 expression
Nucleic Acids Research, 2019 N 6-Methyladenosine (m6A) is a dynamic mRNA modification which regulates protein expression in various posttranscriptional levels. Functional studies of m6A in nervous system have focused on its writers and erasers so far, whether and how m6A readers ...
Mengru Zhuang +9 more
semanticscholar +1 more source