Results 91 to 100 of about 50,535 (307)

Spinal Cord Repair: Strategies to Promote Axon Regeneration

open access: yesNeurobiology of Disease, 2001
Neurons in the central nervous system have a remarkable capacity to regenerate their transected axons when provided with an appropriate growth environment.
Lisa McKerracher
doaj   +1 more source

Protein deacetylases and axonal regeneration

open access: yesNeural Regeneration Research, 2015
10.4103/1673-5374.158333 ; Neural Regeneration Research ; 10 ; 6 ; 870 ...
Ng F., Tang B.L.
openaire   +3 more sources

Nonmulberry Silk Fibroin Doping Boosts Charge Transfer and Charge Injection in Aligned Polypyrrole‐Silk Scaffolds for Low‐Voltage Neurostimulation

open access: yesAdvanced Materials Interfaces, EarlyView.
Conductive silk‐polypyrrole scaffolds couple redox stability with cell‐affinitive peptides present innately in an endogenous silk fibroin, enabling optimized electrical stimulation to drive neurite outgrowth. Findings establish electrochemical‐biological link for biomaterial design rules for smart nerve guidance conduits that can provide low voltage ...
Rajiv Borah   +5 more
wiley   +1 more source

Gene Manipulation Strategies to Identify Molecular Regulators of Axon Regeneration in the Central Nervous System

open access: yesFrontiers in Cellular Neuroscience, 2017
Limited axon regeneration in the injured adult mammalian central nervous system (CNS) usually results in irreversible functional deficits. Both the presence of extrinsic inhibitory molecules at the injury site and the intrinsically low capacity of adult ...
Vinicius T. Ribas, Marcos R. Costa
doaj   +1 more source

Programmable Dimensional Lithography with Digital Micromirror Devices for Multifunctional Microarchitectures

open access: yesAdvanced Materials Technologies, EarlyView.
This review explores recent advances in digital micromirror device (DMD)‐based lithography, focusing on its programmable light modulation, multi‐material compatibility, and dimensional patterning strategies. It highlights innovations from optical system design to materials integration and multifunctional applications, positioning DMD lithography as a ...
Yubin Lee   +5 more
wiley   +1 more source

DLK orchestrates a modular transcriptional response to axon injury with separate roles for Fos and Jun.

open access: yesPLoS Genetics
Axon injury initiates transcriptional reprogramming that in competent cells leads to regeneration. In vertebrate neurons, DLK acts upstream of Jun, STAT and Atf3, core transcription factors that mediate regeneration.
Gibarni Mahata   +3 more
doaj   +1 more source

Cytoskeleton dynamics in axon regeneration

open access: yesCurrent Opinion in Neurobiology, 2018
Recent years have seen cytoskeleton dynamics emerging as a key player in axon regeneration. The cytoskeleton, in particular microtubules and actin, ensures the growth of neuronal processes and maintains the singular, highly polarized shape of neurons. Following injury, adult central axons are tipped by a dystrophic structure, the retraction bulb, which
Blanquie, Oriane, Bradke, Frank
openaire   +3 more sources

Wireless Power Transfer Modalities for Implantable Bioelectronics: Electromagnetic, Acoustic, and Magneto‐Dynamic Perspectives

open access: yesAdvanced Materials Technologies, EarlyView.
This review traces the evolution of wireless power transfer (WPT) for implantable medical devices, spanning electromagnetic, magnetoelectric, acoustic, and magneto‐dynamic systems. Quantitative comparisons of power, distance, and device scale highlight trade‐offs across modalities, while emerging hybrid mechanisms reveal strategies to overcome ...
Junyeop Kim, Yoonseok Park
wiley   +1 more source

RIG‐I Mediated Neuron‐Specific IFN Type 1 Signaling in FUS‐ALS Induces Neurodegeneration and Offers New Biomarker‐Driven Individualized Treatment Options for (FUS‐)ALS

open access: yesAdvanced Science, EarlyView.
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann   +26 more
wiley   +1 more source

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