Results 131 to 140 of about 769,118 (313)

Network analysis of microRNAs, transcription factors, and target genes involved in axon regeneration

open access: yesJournal of Zhejiang University SCIENCE B, 2018
Axon regeneration is crucial for recovery from neurological diseases. Numerous studies have identified several genes, microRNAs (miRNAs), and transcription factors (TFs) that influence axon regeneration. However, the regulatory networks involved have not
Li-ning Su   +5 more
semanticscholar   +1 more source

Computational and AI‐Driven Design of Hydrogels for Bioelectronic Applications

open access: yesAdvanced Electronic Materials, EarlyView.
This review highlights the role of AI in advancing hydrogel design for bioelectronics, exploring natural, and synthetic gels tailored for applications like wound healing, biosensing, and tissue engineering. It emphasizes the synergy between hydrogels, electronics, and AI in creating responsive, multifunctional systems, showcasing recent innovations ...
Rebekah Finster   +2 more
wiley   +1 more source

Designed Biomaterial‐Enhanced Cell Transplantation for Neural Tissue Engineering

open access: yesAggregate, EarlyView.
Biomaterials offer a promising solution for cell transplantation in the central nervous system by creating a protective environment that enhances cell survival, integration, and functional recovery in preclinical models of neurological disorders. ABSTRACT Cell transplantation therapy in the central nervous system is hindered by limited survival and ...
Yun Tang   +3 more
wiley   +1 more source

Modelling axon growing using CTRW [PDF]

open access: yesarXiv, 2015
The main goal of this study is to propose a mathematical model describing paths of the axon growth cones and differences in the behavior of normal and mutant axons. We introduce a probabilistic model for axon growing, such that each family of axons is described as an ensemble of trajectories of a continuous time random walk (CTRW) model under different
arxiv  

Autophagy induction stabilizes microtubules and promotes axon regeneration after spinal cord injury

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2016
Significance Autophagy maintains cellular homoeostasis by bulk or selective degradation of cytoplasmic components including organelles or protein aggregates. Its role in axon regeneration remains speculative.
Miao He   +5 more
semanticscholar   +1 more source

Targeting signaling pathways in neurodegenerative diseases: Quercetin's cellular and molecular mechanisms for neuroprotection

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Quercetin regulates signaling pathways in neurodegenerative diseases, including NF‐κB, sirtuins, and PI3K/Akt. Studies show quercetin improves symptoms and pathology in neurodegenerative models. The study aims to incorporate laboratory research into practical medical treatment, focusing on quercetin's neuroprotective effects and optimal dosage ...
Md. Rezaul Islam   +13 more
wiley   +1 more source

Different Effect of Sox11 in Retinal Ganglion Cells Survival and Axon Regeneration

open access: yesFrontiers in Genetics, 2018
Purpose: The present study examines the role of Sox11 in the initial response of retinal ganglion cells (RGCs) to axon damage and in optic nerve regeneration in mouse.
Ying Li   +4 more
semanticscholar   +1 more source

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