Results 311 to 320 of about 938,041 (332)
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Topological aspects of axonal regeneration
Medical Hypotheses, 2003The fibers making up any sensory system in the spinal cord come from the same cells as do the fibers in peripheral nerves yet severed nerve fibers in the adult spinal cord do not regenerate but damaged peripheral nerves - those in the extremities - do heal themselves.
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Regeneration of axons in the visual system
Restorative Neurology and Neuroscience, 2008This review will describe the unique advantages that are offered by the visual system of mammals and other vertebrates for studying the regenerative responses of the central nervous system (CNS) to injury, and recent insights provided by such studies.
Martin, Berry +4 more
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Gangliosides in Axon Stability and Regeneration
2018Gangliosides are a family of sialic acid-containing glycosphingolipids highly expressed in the nervous system of vertebrates. Over the last 25years, research has unmasked several of their neurobiological functions but the role of gangliosides in the nervous system remains not fully elucidated.
Lopez, Pablo, Báez, Bárbara Beatriz
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Treatment synergy in axon regeneration
Nature Neuroscience, 2016Injured mouse retinal ganglion cells, upon a combination of treatments, can regrow their axons along the entire optic pathway and re-establish connections with their correct brain targets. This can partially restore function.
Krol J, Roska B
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Building bridges to regenerate axons
Science, 2016A secreted factor stimulates glia to mend spinal cord ...
Philip R, Williams, Zhigang, He
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Rho Signaling and Axon Regeneration
2012Several major advances in our understanding of axon regeneration and functional repair in the central nervous system (CNS) together with new insights about molecular signaling pathways have led to development of viable drug candidates to treat spinal cord injury. In this review, we focus on Rho, an intracellular small GTPase that is part of a family of
L, McKerracher +2 more
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The injured axon: intrinsic mechanisms driving axonal regeneration
Trends in NeurosciencesInjury to the central nervous system (CNS) often results in permanent neurological impairments because axons fail to regenerate and re-establish lost synaptic contacts. By contrast, peripheral neurons can activate a pro-regenerative program and regenerate following a nerve lesion.
Tomé, Diogo, Almeida, Ramiro D.
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Neuronal maturation and axon regeneration: unfixing circuitry to enable repair
Nature Reviews NeuroscienceBrett J. Hilton +3 more
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Rewiring Neuronal Glycerolipid Metabolism Determines the Extent of Axon Regeneration
Neuron, 2020Yang Chao +2 more
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