Results 201 to 210 of about 68,124 (256)

Innervation and cargo-specific axonal transport impairments in FUS-ALS mice with gain and loss of function

Simkin RL, Tosolini AP, Mikheenko A, Ule AM, Jin W, Kalmar B, Ahmed M, Lang Q, Lirot F, McLaughlin MF, Price G, Villarroel-Campos D, Greensmith L, Sleigh JN, Cunningham TJ, Schiavo G, Fisher EMC, Fratta P, Birsa N.   +18 more
europepmc   +1 more source

Processivity and BDNF-dependent modulation of signalling endosome axonal transport are impaired in aged mice

Villarroel-Campos D, Rhymes ER, Tosolini AP, Malik B, Vagnoni A, Schiavo G, Sleigh JN.   +6 more
europepmc   +1 more source

Efficient axonal transport of endolysosomes relies on the balanced ratio of microtubule tyrosination and detyrosination.

J Cell Sci
Konietzny A, Han Y, Popp Y, van Bommel B, Sharma A, Delagrange P, Arbez N, Moutin MJ, Peris L, Mikhaylova M.   +9 more
europepmc   +1 more source

The node of Ranvier influences the in vivo axonal transport of mitochondria and signalling endosomes

Tosolini AP, Abatecola F, Negro S, Sleigh JN, Schiavo G.   +4 more
europepmc   +1 more source

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Axonal transport in neuropathy

Muscle & Nerve, 1983
AbstractRecent studies on the distribution of labeled endogenous proteins in the experimental neuropathies induced by streoptozotocin diabetes, galactose feeding, zinc pyridinethione, 2,5‐hexanedione, acrylamide, and p‐bromophenylacetylurea (BPAU) have demonstrated an impaired build up of retrogradely transported material derived from the more distal ...
J, Jakobsen, S, Brimijoin, P, Sidenius
openaire   +2 more sources

A paradigm for axonal transport

Neurochemical Research, 1983
Axonal transport has been extensively studied for a period of 20-30 years, but there is still no general consensus concerning the mechanism by which this transport process operates. An important development in this regard is the recent studies in the physical biochemistry group in the Department of Biochemistry at Monash University where it has been ...
W D, Comper, B N, Preston, L, Austin
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Persistence of Axonal Transport in Isolated Axons of the Mouse

European Journal of Neuroscience, 1993
AbstractWe have examined the hypothesis, for the case of mouse axons, that isolating an axon from its cell body will lead to a rapid failure of fast axonal transport as anterogradely moving organelles vacate the axon in a proximo‐distal direction, and retrogradely moving organelles vacate it in the opposite direction.
R S, Smith, M A, Bisby
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Axonal transport of lipid in goldfish optic axons

Neurochemical Research, 1978
After injection of labeled glycerol, choline, or serine into the eye of goldfish, labeled lipids were axonally transported along the optic nerve to the optic tectum. Although the different precursors were presumably incorporated into somewhat different lipid populations, all three were approximately equally effective in labeling the lipids transported ...
J R, Currie, B, Grafstein, M H, Whitnall, R, Alpert   +3 more
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Fast Axonal Transport in Squid Giant Axon

Science, 1982
Video-enhanced contrast-differential interference contrast microscopy has revealed new features of axonal transport in the giant axon of the squid, where no movement had been detected previously by conventional microscopy. The newly discovered dominant feature is vast numbers of "submicroscopic" particles, probably 30- to 50-nanometer vesicles and ...
R D, Allen, J, Metuzals, I, Tasaki, S T, Brady, S P, Gilbert   +4 more
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Axonal transport and the cytoskeleton

Current Opinion in Neurobiology, 1993
Great advances in the field of axonal transport have been made in the past year, including the identification of new molecular motors associated with microtubules and actin. In addition, studies on the mechanisms of bidirectional fast axonal transport have clarified new aspects of this process, such as the isolation of a kinesin-binding protein ...
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