Results 221 to 230 of about 122,498 (328)

Sequence‐ and Docking‐Site‐Dependent Contributions to Multi‐Site Phosphorylation of an Intrinsically Disordered MAPK Substrate

Advanced Science, EarlyView.
Real‐time NMR spectroscopy is used to study JNK1‐dependent phosphorylation of the intrinsically disordered substrate JIP1, revealing eleven phosphosites with distinct phosphorylation efficiencies. The site‐specific phosphorylation rates are shown to be determined by both the sequence position of the phosphosites relative to the two kinase docking site ...
Thibault Orand, Elise Delaforge, Marion Chenal, Maud Tengo, Torsten Herrmann, Juan Cortés, Pau Bernadó, Malene Ringkjøbing Jensen   +7 more
wiley   +1 more source

DYRK1A Regulates the Bidirectional Axonal Transport of APP in Human-Derived Neurons. [PDF]

J Neurosci, 2022
Fernandez Bessone I, Navarro J, Martinez E, Karmirian K, Holubiec M, Alloatti M, Goto-Silva L, Arnaiz Yepez C, Martins-de-Souza D, Minardi Nascimento J, Bruno L, Saez TM, Rehen SK, Falzone TL.   +13 more
europepmc   +1 more source

Inhibition of kinesin synthesis and rapid anterograde axonal transport in vivo by an antisense oligonucleotide

, 1993
Anil Amaratunga, Peter J. Morin, K S Kosik, Richard E. Fine   +3 more
openalex   +1 more source

Disruption of Axonal Transport and Neuronal Viability by Amyloid Precursor Protein Mutations in Drosophila [PDF]

, 2001
Shermali Gunawardena, Lawrence S.B. Goldstein   +1 more
openalex   +1 more source

Intermediate Filament Protein BFSP1 Maintains Oocyte Asymmetric Division by Modulating Spindle Length

Advanced Science, EarlyView.
Different from mitosis, the female meiosis undergoes asymmetric division that produces haploid oocytes and polar body, which is essential for retaining maternal components to support subsequent fertilization and embryo development. However, the underlying mechanisms are still largely unknown.
Yu Li, Hanwen Zhang, Wenjun Zeng, Yilong Miao, Shaochen Sun, Yu Zhang, Bo Xiong   +6 more
wiley   +1 more source

Presynaptic perspective: Axonal transport defects in neurodevelopmental disorders. [PDF]

J Cell Biol
Xiong GJ, Sheng ZH.
europepmc   +1 more source

TBK1 Knockdown Alleviates Axonal Transport Deficits in Retinal Ganglion Cells Via mTORC1 Activation in a Retinal Damage Mouse Model. [PDF]

Invest Ophthalmol Vis Sci, 2023
Ye M, Hu Y, Zhao B, Mou Q, Ni Y, Luo J, Li L, Zhang H, Zhao Y.   +8 more
europepmc   +1 more source

Polarity of varicosity initiation in central neuron mechanosensation [PDF]

, 2017
Akhmanova, Amack, Andrieux, Baas, Barry, Barry, Barsukova, Benfenati, Bentley, Betz, Beyder, Bosc, Bu, Campàs, Caterina, Chen Gu, Cho, Christensen, Chung, Cosens, Couégnas, David Brody, Debanne, DeFord, Delmas, Deloulme, Eastwood, Elkin, Engler, Fournet, Franze, Gao, Gardner, Gibson, Gilmour, Grevesse, Gu, Gu, Gu, Gu, Gu, Guillaud, Harrington, Hasbani, Hemphill, Iwata, Jukkola, Jukkola, Kanayama, Kang, Koleske, Laurer, Lefèvre, Liedtke, Liedtke, Ligon, Lu, Luo, Margolis, Montell, Morris, Namba, Nikić, Peter Jukkola, Pirollet, Qian Wang, Reeves, Richard, Rishal, Ryskamp, Serrano, Shepherd, Shibasaki, Shitaka, Smith, Staal, Strotmann, Sánchez, Tang-Schomer, Thomas Esparza, Tseng, van Beuningen, Van Essen, Venkatachalam, Wang, Wang, Xu, Xu, Yang, Yi Zhao, Yuanzheng Gu, Zheng, Ziv, Árnadóttir   +93 more
core   +2 more sources

Rabies virus glycoprotein pseudotyping of lentiviral vectors enables retrograde axonal transport and access to the nervous system after peripheral delivery [PDF]

, 2001
Nicholas D. Mazarakis
openalex   +1 more source

Nasal Delivery of Engineered Exosomes via a Thermo‐Sensitive Hydrogel Depot Reprograms Glial Cells for Spinal Cord Repair

Advanced Science, EarlyView.
Engineered macrophage‐derived exosomes overexpressing GNA12 and GNA13 reprogram glial cells to promote neuroprotection and neural regeneration following SCI. A chitosan‐based thermosensitive hydrogel enables sustained intranasal exosome delivery, bypassing systemic barriers and enhancing therapeutic efficacy.
Yangyang Wang, Jingsong Liu, Pengfei Li, Zhibin Peng, Yubo Zhang, Yishu Liu, Mi Li, Xuqiang Gong, Daqian Liu, Enze Xu, Hongbo Yang, Yuanliang Sun, Yan Xu, Yansong Wang   +13 more
wiley   +1 more source