Results 231 to 240 of about 2,309,945 (284)
The node of Ranvier influences the in vivo axonal transport of mitochondria and signalling endosomes
Tosolini AP +4 more
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The Role of Axonal Transport in Glaucoma
International Journal of Molecular Sciences, 2022 Glaucoma is a neurodegenerative disease that affects the retinal ganglion cells (RGCs) and leads to progressive vision loss. The first pathological signs can be seen at the optic nerve head (ONH), the structure where RGC axons leave the retina to compose
Vinicius Toledo Ribas +2 more
exaly +6 more sources
Regulation of Axonal Transport by Protein Kinases [PDF]
Trends in Biochemical Sciences, 2015 The intracellular transport of organelles, proteins, lipids, and RNA along the axon is essential for neuronal function and survival. This process, called axonal transport, is mediated by two classes of ATP-dependent motors, kinesins, and cytoplasmic ...
Giampietro Schiavo, Linda Greensmith
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A paradigm for axonal transport
Neurochemical Research, 1983Axonal transport has been extensively studied for a period of 20-30 years, but there is still no general consensus concerning the mechanism by which this transport process operates. An important development in this regard is the recent studies in the physical biochemistry group in the Department of Biochemistry at Monash University where it has been ...
W D, Comper, B N, Preston, L, Austin
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Axonal transport in neuropathy
Muscle & Nerve, 1983AbstractRecent studies on the distribution of labeled endogenous proteins in the experimental neuropathies induced by streoptozotocin diabetes, galactose feeding, zinc pyridinethione, 2,5‐hexanedione, acrylamide, and p‐bromophenylacetylurea (BPAU) have demonstrated an impaired build up of retrogradely transported material derived from the more distal ...
J, Jakobsen, S, Brimijoin, P, Sidenius
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Persistence of Axonal Transport in Isolated Axons of the Mouse
European Journal of Neuroscience, 1993AbstractWe have examined the hypothesis, for the case of mouse axons, that isolating an axon from its cell body will lead to a rapid failure of fast axonal transport as anterogradely moving organelles vacate the axon in a proximo‐distal direction, and retrogradely moving organelles vacate it in the opposite direction.
R S, Smith, M A, Bisby
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Fast Axonal Transport in Squid Giant Axon
Science, 1982Video-enhanced contrast-differential interference contrast microscopy has revealed new features of axonal transport in the giant axon of the squid, where no movement had been detected previously by conventional microscopy. The newly discovered dominant feature is vast numbers of "submicroscopic" particles, probably 30- to 50-nanometer vesicles and ...
R D, Allen +4 more
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Axonal transport of lipid in goldfish optic axons
Neurochemical Research, 1978After injection of labeled glycerol, choline, or serine into the eye of goldfish, labeled lipids were axonally transported along the optic nerve to the optic tectum. Although the different precursors were presumably incorporated into somewhat different lipid populations, all three were approximately equally effective in labeling the lipids transported ...
J R, Currie +3 more
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Axonal transport and the cytoskeleton
Current Opinion in Neurobiology, 1993Great advances in the field of axonal transport have been made in the past year, including the identification of new molecular motors associated with microtubules and actin. In addition, studies on the mechanisms of bidirectional fast axonal transport have clarified new aspects of this process, such as the isolation of a kinesin-binding protein ...
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