Results 231 to 240 of about 124,572 (294)

Boosting BDNF in muscle rescues impaired axonal transport in a mouse model of DI-CMTC peripheral neuropathy. [PDF]

Neurobiol Dis
Rhymes ER, Simkin RL, Qu J, Villarroel-Campos D, Surana S, Tong Y, Shapiro R, Burgess RW, Yang XL, Schiavo G, Sleigh JN.   +10 more
europepmc   +1 more source

The association between neural crest‐derived glia and melanocyte lineages throughout development and disease

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient cell population that emerges from the dorsal neural tube during neurulation and migrates extensively throughout the embryo. Among their diverse derivatives, glial cells (such as Schwann and satellite ganglionic cells) and melanocytes represent two major lineages. In vitro studies suggested they share a common
Chaya Kalcheim
wiley   +1 more source

Innervation and cargo-specific axonal transport impairments in FUS-ALS mice with gain and loss of function

Simkin RL, Tosolini AP, Mikheenko A, Ule AM, Jin W, Kalmar B, Ahmed M, Lang Q, Lirot F, McLaughlin MF, Price G, Villarroel-Campos D, Greensmith L, Sleigh JN, Cunningham TJ, Schiavo G, Fisher EMC, Fratta P, Birsa N.   +18 more
europepmc   +1 more source

Swedish Alzheimer's disease variant perturbs activity of retrograde molecular motors and causes widespread derangement of axonal transport pathways. [PDF]

J Biol Chem
Feole M, Pozo Devoto VM, Dragišić N, Arnaiz C, Bianchelli J, Texlová K, Kovačovicova K, Novotny JS, Havas D, Falzone TL, Stokin GB.   +10 more
europepmc   +1 more source

Processivity and BDNF-dependent modulation of signalling endosome axonal transport are impaired in aged mice

Villarroel-Campos D, Rhymes ER, Tosolini AP, Malik B, Vagnoni A, Schiavo G, Sleigh JN.   +6 more
europepmc   +1 more source

Efficient axonal transport of endolysosomes relies on the balanced ratio of microtubule tyrosination and detyrosination.

J Cell Sci
Konietzny A, Han Y, Popp Y, van Bommel B, Sharma A, Delagrange P, Arbez N, Moutin MJ, Peris L, Mikhaylova M.   +9 more
europepmc   +1 more source

Huntingtin as an Actin Organizer: Structural and Functional Insights

Cytoskeleton, EarlyView.
M. Capizzi, S. Humbert
wiley   +1 more source

The node of Ranvier influences thein vivoaxonal transport of mitochondria and signalling endosomes

Tosolini AP, Abatecola F, Negro S, Sleigh JN, Schiavo G.   +4 more
europepmc   +1 more source

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Axonal transport versus dendritic transport

Journal of Neurobiology, 2003
AbstractNeurons have polarized processes for information output and input, axons, and dendrites. This polarized architecture is essential for the neuronal function. An increasing number of molecular components that mediate neuronal polarity establishment have been characterized over the past few years.
Mitsutoshi, Setou, Takahiro, Hayasaka, Ikuko, Yao   +2 more
openaire   +2 more sources

Fast Axonal Transport in Squid Giant Axon

Science, 1982
Video-enhanced contrast-differential interference contrast microscopy has revealed new features of axonal transport in the giant axon of the squid, where no movement had been detected previously by conventional microscopy. The newly discovered dominant feature is vast numbers of "submicroscopic" particles, probably 30- to 50-nanometer vesicles and ...
R D, Allen, J, Metuzals, I, Tasaki, S T, Brady, S P, Gilbert   +4 more
openaire   +2 more sources