Results 31 to 40 of about 188,959 (299)

Interferon inhibits the release of herpes simplex virus-1 from the axons of sensory neurons

open access: yesmBio, 2023
Herpes simplex virus-1 (HSV-1) has evolved mechanisms to evade the host immune system and limit the antiviral effects induced by interferon (IFN) produced by local epithelial and immune cells.
Kevin Danastas   +6 more
doaj   +1 more source

Polychlorinated Biphenyls (PCBs): Risk Factors for Autism Spectrum Disorder?

open access: yesToxics, 2020
Autism spectrum disorder (ASD) includes a group of multifactorial neurodevelopmental disorders defined clinically by core deficits in social reciprocity and communication, restrictive interests and repetitive behaviors.
Harmanpreet Kaur Panesar   +3 more
doaj   +1 more source

Axon and Myelin Morphology in Animal and Human Spinal Cord

open access: yesFrontiers in Neuroanatomy, 2017
Characterizing precisely the microstructure of axons, their density, size and myelination is of interest for the neuroscientific community, for example to help maximize the outcome of studies on white matter (WM) pathologies of the spinal cord (SC).
Ariane Saliani   +7 more
doaj   +1 more source

Neurorrhaphy in Presence of Polyethylene Glycol Enables Immediate Electrophysiological Conduction in Porcine Model of Facial Nerve Injury

open access: yesFrontiers in Surgery, 2022
Facial nerve trauma often leads to disfiguring facial muscle paralysis. Despite several promising advancements, facial nerve repair procedures often do not lead to complete functional recovery.
Dmitriy Petrov   +14 more
doaj   +1 more source

Intra-axonal mechanisms driving axon regeneration

open access: yesBrain Research, 2020
Traumatic injury to the peripheral and central nervous systems very often causes axotomy, where an axon loses connections with its target resulting in loss of function. The axon segments distal to the injury site lose connection with the cell body and degenerate.
Terika P. Smith   +3 more
openaire   +3 more sources

Human umbilical cord mesenchymal stem cells promote peripheral nerve repair via paracrine mechanisms

open access: yesNeural Regeneration Research, 2015
Human umbilical cord-derived mesenchymal stem cells (hUCMSCs) represent a promising young-state stem cell source for cell-based therapy. hUCMSC transplantation into the transected sciatic nerve promotes axonal regeneration and functional recovery.
Zhi-yuan Guo   +4 more
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Large-Scale Mapping of Axonal Arbors Using High-Density Microelectrode Arrays

open access: yesFrontiers in Cellular Neuroscience, 2019
Understanding the role of axons in neuronal information processing is a fundamental task in neuroscience. Over the last years, sophisticated patch-clamp investigations have provided unexpected and exciting data on axonal phenomena and functioning, but ...
Torsten Bullmann   +10 more
doaj   +1 more source

How neurons maintain their axons long-term: an integrated view of axon biology and pathology

open access: yesFrontiers in Neuroscience, 2023
Axons are processes of neurons, up to a metre long, that form the essential biological cables wiring nervous systems. They must survive, often far away from their cell bodies and up to a century in humans.
Gaynor Smith   +3 more
doaj   +1 more source

Mitochondrial DNA disorders in neuromuscular diseases in diverse populations

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Abstract Neuromuscular features are common in mitochondrial DNA (mtDNA) disorders. The genetic architecture of mtDNA disorders in diverse populations is poorly understood. We analysed mtDNA variants from whole‐exome sequencing data in neuromuscular patients from South Africa, Brazil, India, Turkey and Zambia. In 998 individuals, there were two definite
Fei Gao   +34 more
wiley   +1 more source

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