Results 31 to 40 of about 271,417 (354)
Estimating axon radius using diffusion-relaxation MRI: calibrating a surface-based relaxation model with histology [PDF]
Axon radius is a potential biomarker for brain diseases and a crucial tissue microstructure parameter that determines the speed of action potentials. Diffusion MRI (dMRI) allows non-invasive estimation of axon radius, but accurately estimating the radius of axons in the human brain is challenging.
arxiv +1 more source
Modeling of interstitial branching of axonal networks [PDF]
A single axon can generate branches connecting with plenty synaptic targets. Process of branching is very important for making connections in central nervous system. The interstitial branching along primary axon shaft occurs during nervous system development. Growing axon makes pause in its movement and leaves active points behind its terminal. The new
arxiv +1 more source
Neural activity promotes long distance, target-specific regeneration of adult retinal axons
Axons in the mammalian CNS fail to regenerate after injury. Here we show that if the activity of mouse retinal ganglion cells (RGCs) is increased by visual stimulation or using chemogenetics, their axons regenerate.
Jung-Hwan A. Lim+7 more
semanticscholar +1 more source
Herpes simplex virus (HSV) and varicella zoster virus (VZV) rely on transport of virus particles in neuronal axons to spread from sites of viral latency in sensory ganglia to peripheral tissues then on to other hosts.
Steven Adamou+2 more
doaj +1 more source
The impact of realistic axonal shape on axon diameter estimation using diffusion MRI [PDF]
To study axonal microstructure with diffusion MRI, axons are typically modeled as straight impermeable cylinders, whereby the transverse diffusion MRI signal can be made sensitive to the cylinder's inner diameter. However, the shape of a real axon varies along the axon direction, which couples the longitudinal and transverse diffusion of the overall ...
arxiv +1 more source
A large fraction of neocortical myelin ensheathes axons of local inhibitory neurons
Myelin is best known for its role in increasing the conduction velocity and metabolic efficiency of long-range excitatory axons. Accordingly, the myelin observed in neocortical gray matter is thought to mostly ensheath excitatory axons connecting to ...
Kristina D. Micheva+6 more
semanticscholar +1 more source
microRNAs in axon guidance [PDF]
Brain wiring is a highly intricate process in which trillions of neuronal connections are established. Its initial phase is particularly crucial in establishing the general framework of neuronal circuits. During this early step, differentiating neurons extend axons, which reach their target by navigating through a complex environment with extreme ...
Iyer, A. N., Bellon, A., Baudet, M. L.
openaire +3 more sources
Action potential timing is fundamental to information processing; however, its determinants are not fully understood. Here we report unexpected structural specializations in the Ranvier nodes and internodes of auditory brainstem axons involved in sound ...
Marc C. Ford+8 more
semanticscholar +1 more source
Sodium channel inactivation kinetics of rat sensory and motor nerve fibres and their modulation by glutathione [PDF]
Na+ channel currents of rat motor and sensory nerve fibres were studied with the patch-clamp technique on enzymatically demyelinated axons. Differences between motor and sensory fibres in multi-channel inactivation kinetics and the gating of late single ...
Grafe, Peter+2 more
core +1 more source
Neuron Names: A Gene- and Property-Based Name Format, With Special Reference to Cortical Neurons
Precision in neuron names is increasingly needed. We are entering a new era in which classical anatomical criteria are only the beginning toward defining the identity of a neuron as carried in its name.
Gordon M. Shepherd+14 more
doaj +1 more source