Results 61 to 70 of about 559 (115)

Red Yeast Rice or Lovastatin? A Comparative Evaluation of Safety and Efficacy Through a Multifaceted Approach

Phytotherapy Research, Volume 39, Issue 1, Page 264-281, January 2025.
ABSTRACT The increasing use of red yeast rice (RYR) as a natural supplement to manage blood cholesterol levels is driven by its active compound, monacolin K (MK), which is chemically identical to the statin drug lovastatin (LOV). Despite its growing popularity, concerns persists regarding the safety and efficacy of RYR compared to pure statins.
Giovanna Rigillo, Giulia Baini, Renato Bruni, Giulia Puja, Elisabetta Miraldi, Luca Pani, Fabio Tascedda, Marco Biagi   +7 more
wiley   +1 more source

Impact of Nigrospora oryzae‐Derived Natural Products on Photosynthesis and Oxidative Stress in Eichhornia crassipes

Physiologia Plantarum, Volume 177, Issue 1, January/February 2025.
Abstract Interest in natural herbicides has been growing due to government policies restricting synthetic herbicide use in many countries. In that regard, this study investigates the potential of Nigrospora oryzae extract as a natural herbicide against the aquatic invasive weed Eichhornia crassipes.
Chamroon Laosinwattana, Nutcha Manichart, Pattharin Wichittrakarn, Kaori Yoneyama, Montinee Teerarak, Hataichanok Passara   +5 more
wiley   +1 more source

Nidulantes of Aspergillus (Formerly Emericella): A Treasure Trove of Chemical Diversity and Biological Activities

Metabolites, 2020
The genus Emericella (Ascomycota) includes more than thirty species with worldwide distribution across many ecosystems. It is considered a rich source of diverse metabolites.
Najla Ali Alburae, Afrah E. Mohammed, Hajer Saeed Alorfi, Adnan Jaman Turki, Hani Zakaria Asfour, Walied Mohamed Alarif, Ahmed Abdel-Lateff   +6 more
doaj   +1 more source

Anticancer Effect of Mycotoxins From Penicillium aurantiogriseum: Exploration of Natural Product Potential

International Journal of Microbiology, Volume 2024, Issue 1, 2024.
Research into biologically natural substances with antitumor properties, known for their potential to induce fewer side effects and exhibit specificity toward cancerous cells, remains imperative. The pressing demand for novel agents in cancer therapy underscores the intensive investigation of natural products from microorganisms.
Assia Bouhoudan, Joaira Bakkach, Mustapha Khaddor, Nadira Mourabit, Phull Abdul Rehman   +4 more
wiley   +1 more source

Fungi as a Potential Source of Pigments: Harnessing Filamentous Fungi

Frontiers in Chemistry, 2020
The growing concern over the harmful effects of synthetic colorants on both the consumer and the environment has raised a strong interest in natural coloring alternatives.
Rishu Kalra, Xavier A. Conlan, Mayurika Goel   +2 more
doaj   +1 more source

Design of Fungal Co-Cultivation Based on Comparative Metabolomics and Bioactivity for Discovery of Marine Fungal Agrochemicals

Marine Drugs, 2020
Microbial co-cultivation is employed for awakening silent biosynthetic gene clusters (BGCs) to enhance chemical diversity. However, the selection of appropriate partners for co-cultivation remains a challenge.
Ernest Oppong-Danquah, Paulina Budnicka, Martina Blümel, Deniz Tasdemir   +3 more
doaj   +1 more source

Deletion of the Class 1 Histone Deacetylase PsHos2 Induces Secondary Metabolic Perturbations in the Sea Cucumber-Associated Penicillium sclerotiorum

Fermentation
The long-term coexistence of sea cucumber-associated microorganisms with their host enables them to jointly withstand the unique marine ecological environment, and possess great potential for producing various natural products.
Peipei Zhao, Jiaying Lin, Qingqing Zhang, Tanghui Zhang, Guoliang Zhu, Chengwei Liu, Qinghua Wu, Jianzhao Qi, Minglei Li, Lixin Zhang, Xuekui Xia   +10 more
doaj   +1 more source

Supercritical CO2 extraction of solid-state cultivation fungus producing azaphilone polyketides

Green Analytical Chemistry
Supercritical Fluid Extraction (SFE) methods dedicated to microorganisms specialized metabolites are very scarce in the literature and limited to liquid cultivation.
Téo Hebra, Véronique Eparvier, David Touboul   +2 more
doaj   +1 more source

Chromatin-mediated upregulation of Monascus pigments in Talaromyces purpurogenus OUCMDZ-019 via disruption of Ash2

Mycology
Monascus pigments (MPs) are important azaphilone-type polyketide pigments, yet yield control, stability, and safety pose challenges. Using an epigenetic derepression strategy, we constructed an Ash2 deletion mutant in the acidophilic fungus Talaromyces ...
Chengfeng Hou, Deng Yu, Yuqing Wang, Peng Fu, Weiming Zhu, Yi Wang   +5 more
doaj   +1 more source

The screening for marine fungal strains with high potential in alkaloids production by in situ colony assay and LC-MS/MS based secondary metabolic profiling. [PDF]

Front Microbiol, 2023
Lu T, Liu Y, Zhou L, Liao Q, Nie Y, Wang X, Lei X, Hong P, Feng Y, Hu X, Zhang Y.   +10 more
europepmc   +1 more source