Results 71 to 80 of about 806 (182)

Harnessing Molecular and Bioactivity Network Analysis to Prioritize Antibacterial Compound Isolation From Ant‐Associated Fungi

Phytochemical Analysis, Volume 36, Issue 5, Page 1351-1366, July 2025.
ABSTRACT Introduction Antimicrobial resistance is a global public health problem that requires the development of new bioactive compounds. In this context, metabolomic analyses can expedite the research of fungal metabolites as a valuable resource. Objectives To investigate the metabolic profiles and isolate antibacterial compounds from micromycetes ...
Ángel S. Aguilar‐Colorado, Jesús Morales‐Jiménez, José Rivera‐Chávez   +2 more
wiley   +1 more source

Lienhwalides: Unique Tropolone–Maleidride Hybrids from Hypoxylon lienhwacheense

ChemBioChem, Volume 26, Issue 10, May 27, 2025.
Lienhwalides are novel tropolone–maleidride hybrid molecules unique in nature. Absolute configuration is solved by semisynthetic approaches and X‐ray analysis. Interplay between both lwt and lwm biosynthetic gene clusters is responsible for the production of lienhwalides.
Katharina Schmidt, Esteban Charria‐Girón, Tatiana E. Gorelik, Christian Kleeberg, Jackson M. Muema, Simone Heitkämper, Bart Verwaaijen, Eric Kuhnert, Jennifer Gerke, Jörn Kalinowski, Kevin D. Hyde, Marc Stadler, Russell Cox, Frank Surup   +13 more
wiley   +1 more source

Synthesis of the Azaphilones Using Copper‐Mediated Enantioselective Oxidative Dearomatization. [PDF]

ChemInform, 2005
An approach to the asymmetric synthesis of the azaphilone natural products is reported involving copper-mediated enantioselective oxidative dearomatization of o-alkynylbenzaldehydes. The approach was successfully applied to the synthesis of (-)-S-15183a and several unnatural azaphilones.
Jianglong, Zhu, Nicholas P, Grigoriadis, Jonathan P, Lee, John A, Porco   +3 more
openaire   +2 more sources

Antibacterial Azaphilones from an Endophytic Fungus, Colletotrichum sp BS4

, 2016
Three new compounds, colletotrichones A-C (1-3), and one known compound, chermesinone B (4a), were isolated from an endophytic fungus, Colletotrichum sp.
Golz, Christopher, Kusari, Parijat, Kusari, Souvik, Laatsch, Hartmut, Spiteller, Michael, Wang, W., Kayser, Oliver, Strohmann, Carsten   +7 more
core   +1 more source

Miniaturized Cultivation Profiling (MATRIX)-Facilitated Discovery of Noonazines A–C and Noonaphilone A from an Australian Marine-Derived Fungus, Aspergillus noonimiae CMB-M0339

Marine Drugs
Subjecting the Australian marine-derived fungus Aspergillus noonimiae CMB-M0339 to cultivation profiling using an innovative miniaturized 24-well plate format (MATRIX) enabled access to new examples of the rare class of 2,6-diketopiperazines, noonazines ...
Sarani Kankanamge, Paul V. Bernhardt, Zeinab G. Khalil, Robert J. Capon   +3 more
doaj   +1 more source

Induction of Secondary Metabolite Biosynthesis by Deleting the Histone Deacetylase HdaA in the Marine-Derived Fungus Aspergillus terreus RA2905

Journal of Fungi, 2022
Aspergillus terreus is well-known for its ability to biosynthesize valuable pharmaceuticals as well as structurally unique secondary metabolites. However, numerous promising cryptic secondary metabolites in this strain regulated by silent gene clusters ...
Yao-Yao Zheng, Zhong-Lian Ma, Jing-Shuai Wu, Chang-Lun Shao, Guang-Shan Yao, Chang-Yun Wang   +5 more
doaj   +1 more source

Biofertilizer Industry and Research Developments in China: A Mini‐Review

Microbial Biotechnology, Volume 18, Issue 5, May 2025.
This review discusses the transition from chemical fertilizers to biofertilizers in China, highlighting the risks of chemical overuse, the booming biofertilizer market, and regulatory support. It also explores the challenges in biofertilizer development and advances in microbial research in China, highlighting biofertilizers' role in enhancing ...
Xinli Sun, Zhihui Xu, Nan Zhang, Youzhi Miao, Chao Zhang, Xiaoli Ma, Qirong Shen, Ruifu Zhang   +7 more
wiley   +1 more source

New Metabolite With Inhibitory Activity Against α-Glucosidase and α-Amylase From Endophytic

Natural Product Communications, 2020
An efficient bioactive tracking separation strategy based on liquid-liquid extraction and high-speed counter-current chromatography (HSCCC) was developed and used to isolate bioactive natural products from the endophytic fungus Chaetomium globosum ...
Jianzhao Qi, Dacheng Wang, Xia Yin, Qiang Zhang, Jin-Ming Gao   +4 more
doaj   +1 more source

Scientific Opinion on additional scientific data related to the safety of monacolins from red yeast rice submitted pursuant to Article 8(4) of Regulation (EC) No 1925/2006

EFSA Journal, Volume 23, Issue 2, February 2025.
Abstract The Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver a scientific opinion on the safety of monacolins from red yeast rice (RYR), which have been placed under Union scrutiny in Part C of Annex III in accordance with Article 8(4) of Regulation (EC) No 1925/2006.
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Dominique Turck, Torsten Bohn, Montaña Cámara, Jacqueline Castenmiller, Stefaan De Henauw, Karen Ildico Hirsch‐Ernst, Ángeles Jos, Inge Mangelsdorf, Breige McNulty, Androniki Naska, Kristina Pentieva, Alfonso Siani, Frank Thies, Leonard Matijević, Silvia Valtueña Martinez, Alexandre Maciuk   +17 more
wiley   +1 more source

Red Yeast Rice or Lovastatin? A Comparative Evaluation of Safety and Efficacy Through a Multifaceted Approach

Phytotherapy Research, Volume 39, Issue 1, Page 264-281, January 2025.
ABSTRACT The increasing use of red yeast rice (RYR) as a natural supplement to manage blood cholesterol levels is driven by its active compound, monacolin K (MK), which is chemically identical to the statin drug lovastatin (LOV). Despite its growing popularity, concerns persists regarding the safety and efficacy of RYR compared to pure statins.
Giovanna Rigillo, Giulia Baini, Renato Bruni, Giulia Puja, Elisabetta Miraldi, Luca Pani, Fabio Tascedda, Marco Biagi   +7 more
wiley   +1 more source