Results 91 to 100 of about 806 (182)

Design of Fungal Co-Cultivation Based on Comparative Metabolomics and Bioactivity for Discovery of Marine Fungal Agrochemicals

Marine Drugs, 2020
Microbial co-cultivation is employed for awakening silent biosynthetic gene clusters (BGCs) to enhance chemical diversity. However, the selection of appropriate partners for co-cultivation remains a challenge.
Ernest Oppong-Danquah, Paulina Budnicka, Martina Blümel, Deniz Tasdemir   +3 more
doaj   +1 more source

Cytotoxic and Antimalarial Azaphilones from Chaetomium longirostre

, 2016
Four new azaphilones named longirostrerones A–D (1–4) and three known sterols, ergosteryl palmitate, ergosterol, and ergosterol peroxide, have been isolated from ethyl acetate extract of the fungus Chaetomium longirostre. These structures were determined
Somdej Kanokmedhakul (536848), Kasem Soytong (547959), Natcha Panthama (666149), Kwanjai Kanokmedhakul (536850)   +3 more
core   +1 more source

Penicilones A–D, Anti-MRSA Azaphilones from the Marine-Derived Fungus Penicillium janthinellum HK1‑6

, 2017
Four new azaphilones, penicilones A–D (1–4), were isolated from the mangrove rhizosphere soil-derived fungus Penicillium janthinellum HK1-6. Their planar structures and absolute configurations were determined by extensive analysis of NMR spectroscopic ...
Zhi-Qi Chen (3805393), Min Chen (147733), Feng-Min Zhang (80145), Yang Chen (9737), Nan-Xing Shen (3805390)   +4 more
core   +1 more source

High-resolution mass spectrometry and hydrogen/deuterium exchange study of mitorubrin azaphilones and nitrogenized analogues

, 2012
International audienceAzaphilones represent numerous groups of wild fungal secondary metabolites that exhibit exceptional tendency to bind to nitrogen atoms in various molecules, especially those containing the amine group.
Tabet, Jean-Claude, Lesage, Denis, Stankov-Jovanovic, Vesna, Svilar, Ljubica, Dossmann, Héloïse   +4 more
core   +1 more source

Deletion of the Class 1 Histone Deacetylase PsHos2 Induces Secondary Metabolic Perturbations in the Sea Cucumber-Associated Penicillium sclerotiorum

Fermentation
The long-term coexistence of sea cucumber-associated microorganisms with their host enables them to jointly withstand the unique marine ecological environment, and possess great potential for producing various natural products.
Peipei Zhao, Jiaying Lin, Qingqing Zhang, Tanghui Zhang, Guoliang Zhu, Chengwei Liu, Qinghua Wu, Jianzhao Qi, Minglei Li, Lixin Zhang, Xuekui Xia   +10 more
doaj   +1 more source

Brominated Azaphilones from the Sponge-Associated Fungus Penicillium canescens Strain 4.14.6a

, 2019
The fungus Penicillium canescens was isolated from the inner tissue of the Mediterranian sponge Agelas oroides. Fermentation of the fungus on solid rice medium yielded one new chlorinated diphenyl ether (1) and 13 known compounds (2–14).
Zhen Liu (74646), Ferhat Can Özkaya, Wenhan Lin, Zhen Liu, Rudolf Hartmann (829758), Malte Plenker (7054448), Werner E. G. Müller (1840291), Marian Frank, Attila Mándi, Attila Mándi (1476106), Peter Proksch, Rudolf Hartmann, Alexandra Hamacher, Werner E. G. Müller, Matthias U. Kassack, Marian Frank (7054445), Tibor Kurtán, Wenhan Lin (471132), Matthias U. Kassack (534448), Peter Proksch (460847), Ferhat Can Özkaya (7054451), Tibor Kurtán (1476103), Malte Plenker, Alexandra Hamacher (534446)   +23 more
core   +1 more source

Table_1_Phytotoxic Azaphilones From the Mangrove-Derived Fungus Penicillium sclerotiorum HY5.DOCX

, 2022
Mangrove is a unique marine ecosystem growing in the intertidal zone of tropical and subtropical coast, with the characteristics of hypoxia tolerance, high salinity, and high humidity.
Xi Gao (369965), Dong-Lin Zhao (1523338), Yi-Qiang Li (8846192), Ming-Xian Lan (12431316), Xian-Bo Wang (9524218), Guo-Xing Wu (103247), Wei Wang (17594), Ji-Lin Ding (12431313), Cheng-Sheng Zhang (8846195), Mei Wang (130842)   +9 more
core   +1 more source

Azaphilones and p-Terphenyls from the Mangrove Endophytic Fungus Penicillium chermesinum (ZH4-E2) Isolated from the South China Sea

, 2016
Eight secondary metabolites, including three new azaphilones (chermesinones A–C, 1–3), three new p-terphenyls (6′-O-desmethylterphenyllin, 4; 3-hydroxy-6′-O-desmethylterphenyllin, 5; 3′′-deoxy-6′-O-desmethylcandidusin B, 7), and two known p-terphenyls (6,
Lin Ma (23007), Ze’en Xiao (1958215), Lan Liu (88052), Yongcheng Lin (776525), Xiaojun Feng (231627), Yongjun Lu (421649), Zhigang She (536569), Hanxiang Li (536567), Hongbo Huang (773075), Jianhua Ju (773073)   +9 more
core   +3 more sources

Antimicrobial Azaphilones from the Xylariaceous Inedible Mushrooms

International Journal of Medicinal Mushrooms, 2005
In the course of our investigation of biologically active substances from inedible mushrooms, we studied the chemical constituents of six species belonging to the Xylariaceae family (Sardariomycetideae) and isolated various types of azaphilone derivatives, which showed moderate to strong antimicrobial activity, such as entonaemins A–C (1–3), together ...
Dang Ngoc Quang, Toshihiro Hashimoto, Niko Radulovic, Marc Stadler, Yoshinori Asakawa   +4 more
openaire   +1 more source

Azaphilones from an Endophytic Penicillium sp. Prevent Neuronal Cell Death via Inhibition of MAPKs and Reduction of Bax/Bcl‑2 Ratio

, 2021
Fourteen azaphilone-type polyketides (1–14), including nine new ones (1–6 and 8–10), were isolated from cultures of Vitex rotundifolia-associated Penicillium sp.
Jaekyeong Kim, Hyukjae Choi (1416751), Geum Jin Kim, Ki Sung Kang, Stephen T. Deyrup (2309533), Sunghee Bang, Stephen T. Deyrup, SungJin Kim, Sang Hee Shim (683665), SungJin Kim (11260919), Ji Yun Baek (11260913), Ki Sung Kang (362763), Geum Jin Kim (4280122), Ji Yun Baek, Hyukjae Choi, Jaekyeong Kim (11260916), Sang Hee Shim, Sunghee Bang (4024820)   +17 more
core   +1 more source