Results 31 to 40 of about 1,059 (150)
Pharmaceuticals, 2022 The main protease (Mpro) is a potential druggable target in SARS-CoV-2 replication. Herein, an in silico study was conducted to mine for Mpro inhibitors from toxin sources.
Mahmoud A. A. Ibrahim +11 more
doaj +1 more source
Harmful algae diversity from a coastal upwelling system detected by high-throughput sequencing
Frontiers in Marine Science, 2023 IntroductionIn recent years, environmental DNA (eDNA) amplicon sequencing has been used to unveil plankton diversity in the field. Nevertheless, molecular methods, such as this, are rarely used in harmful algal bloom (HAB) monitoring programs, which ...
Raquel Ríos-Castro +6 more
doaj +1 more source
Studies on the immunosuppressive effects and detection of naturally-occuring toxins [PDF]
, 2012 Episodes of toxin-producing phytoplankton occur worldwide, causing both animal and human fatalities. Toxicity occurs through consumption of phycotoxins, including azaspiracid, which accumulate in filter-feeding shellfish. Microcystins are hepatotoxins,
Stack, Edwina C.
core +2 more sources
Natural Product Communications, 2008 The trioxadispiroketal residue in the marine biotoxin azaspiracid-1, which exists in a configuration capable of exhibiting a double anomeric effect, is believed to be the thermodynamically most stable bis-spiroketal diastereomer.
Jialiang Li, Xiaohua Li, David R. Mootoo
doaj +1 more source
Absorption and Effect of Azaspiracid-1 Over the Human Intestinal Barrier
Cellular Physiology and Biochemistry, 2017 Background: Azaspiracids (AZAs) are marine biotoxins produced by the dinoflagellates genera Azadinium and Amphidoma. These toxins cause azaspiracid poisoning (AZP), characterized by severe gastrointestinal illness in humans after the consumption of ...
Paula Abal +6 more
doaj +1 more source
Toxins, 2020 Many detection methods for phycotoxins, bioactive compounds produced by harmful algae, focus on one compound or a class of related compounds. Multiple harmful algal species often co-occur in the environment, however, emphasizing the need to analyze for ...
Michelle D. Onofrio +3 more
doaj +1 more source
Marine Biotoxins in Whole and Processed Scallops from the Argentine Sea
Marine Drugs, 2022 Harmful algal blooms are an increasing worldwide threat to the seafood industry and human health as a consequence of the natural production of biotoxins that can accumulate in shellfish.
Alejandra B. Goya +8 more
doaj +1 more source
LC-MS/MS method for the detection of multiple classes of shellfish toxins
Czech Journal of Food Sciences, 2019 Marine shellfish toxins are seafood safety problems of global concern. Herein the analysis of six shellfish toxins, regulated by European Union, with one single run by LC-MS/MS with acidic mobile phase was developed.
Ling Jan Chiou +2 more
doaj +1 more source
Toxins, 2016 Phycotoxins are monitored in seafood because they can cause food poisonings in humans. Phycotoxins do not only occur singly but also as mixtures in shellfish. The aim of this study was to evaluate the in vitro toxic interactions of binary combinations of
Pierre-Jean Ferron +4 more
doaj +1 more source
Total synthesis and confirmation of the revised structures of azaspiracid-2 and azaspiracid-3
, 2006 The 39 steps: The recently proposed revised structures of azaspiracid-2 and -3 (see picture), the two most potent members of the azaspiracid family, have been confirmed through the total syntheses of the two compounds. These 39-step syntheses represent a
Nicolaou, K. +4 more
core +1 more source