Results 31 to 40 of about 1,863 (161)
Angewandte Chemie, EarlyView.π‐Extended COUPY dyes, obtained by vinylogation of coumarin‐based COUPY scaffolds, shift absorption, and emission deep into the NIR region while preserving compactness and synthetic accessibility. These bright, photostable dyes enable live‐cell imaging, FLIM, and site‐specific peptide conjugation, offering a modular platform for targeted bioimaging and
Diego Abad‐Montero +11 more
wiley +2 more sources
Studies on the interaction of isocyanides with imines: reaction scope and mechanistic variations
Beilstein Journal of Organic Chemistry, 2014 The interaction of imines with isocyanides has been studied. The main product results from a sequential process involving the attack of two units of isocyanide, under Lewis acid catalysis, upon the carbon–nitrogen double bond of the imine to form the 4 ...
Ouldouz Ghashghaei +4 more
doaj +1 more source
Synthesis of some azetidonone and 1, 3-oxazepine deritives from thymol [PDF]
مجلة التربية والعلم, 2013 A series of some azetidines -2-one derivative (11-16) have been synthesized by cyclocondensation of various hydrazones derivatives (3-10) with chloroacetyl chloride in the presence of triethylamine. Hydrazones (3-10) were synthesized from the reaction of
A. kh. Ahmad, Linda R. Butti
doaj +1 more source
Nature Communications, 2022 Current treatments for toxoplasmosis are limited by adverse reactions and inability to cure chronic infections dominated by semi-dormant cyst forms. Here the authors demonstrate the potential of small molecule inhibitors of PheRS for controlling acute ...
Joshua B. Radke +12 more
doaj +1 more source
Facile and Green Synthesis of Saturated Cyclic Amines
Molecules, 2017 Single-nitrogen containing saturated cyclic amines are an important part of both natural and synthetic bioactive compounds. A number of methodologies have been developed for the synthesis of aziridines, azetidines, pyrrolidines, piperidines, azepanes and
Arruje Hameed +7 more
doaj +1 more source
Chiral donor–acceptor azetines as powerful reactants for synthesis of amino acid derivatives
Nature Communications, 2019 Chiral 3-azetidinones are structural analogues of medicinally relevant β-lactams, however their synthesis and reactivity are underexplored. Here, the authors show a highly enantioselective copper-catalyzed [3 + 1]-cycloaddition generating 2-azetidines ...
Kostiantyn O. Marichev +7 more
doaj +1 more source
Advanced Science, EarlyView.A novel epitranscriptomic mechanism in rheumatoid arthritis is uncovered: NSUN2 promotes disease via m5C‐dependent stabilization of ICMT mRNA, fueling the migration and invasion of pathogenic RA FLS. Targeting this axis with engineered nanoparticles (Ce/SAA NPs) effectively inhibits disease progression, presenting a precise therapeutic strategy ...
Ruiru Li +15 more
wiley +1 more source
Advanced Science, EarlyView.Metal‐anode batteries using Li, Na, Mg, and Ca offer exceptionally high energy density, but dendrites, unstable interphases, cracking, and pore formation hinder durability and safety. This review shows how careful electrolyte and interphase design can stabilize these reactive metals.
Jian Pan +3 more
wiley +1 more source
Visible‐Light‐Mediated Lewis Acid‐Catalyzed Diradical Hydrogen Atom Transfer Reaction of Enamides
Advanced Science, EarlyView.The Lewis acid catalysis was crucial for the success of the DHAT reaction of enamides by lowering the energy of the triplet excited state and modulating the reactivity of the formed diradical intermediate in a carbon‐to‐carbon 1,5‐DHAT and consequent cyclization that allows the functionalization of C(sp3)−H bonds to construct a variety of novel β ...
Yao Huang +5 more
wiley +1 more source
Molecules, 2016 Electron transfer involving nucleic acids and their derivatives is an important field in bioorganic chemistry, specifically in connection with its role in the photo-driven DNA damage and repair.
Ana B. Fraga-Timiraos +4 more
doaj +1 more source