Results 31 to 40 of about 29,405 (265)

Orthogonal, metal-free surface modification by strain-promoted azide–alkyne and nitrile oxide–alkene/alkyne cycloadditions [PDF]

, 2012
In this article we present a fast and efficient methodology for biochemical surface patterning under extremely mild conditions. Micropatterned azide/benzaldoxime-surfaces were prepared by microcontact printing of a heterobifunctional cyclooctyne oxime ...
Arlinghaus, Heinrich F, Burley, Glenn A, Ravoo, Bart Jan, Rinnen, Stefan, Schulz, Christian, Singh, Ishwar, Wendeln, Christian   +6 more
core   +1 more source

Dinuclear Copper(I) Thiodiacetate Complex-Mediated Expeditious Synthesis of the Chlorine-Containing Cyclen-Cored 36-Glucose-Coated Glycodendrimer

Journal of Chemistry, 2021
High-sugar-tethered glycodendrimers are a remarkable tool in glycobiology for the investigation of carbohydrate-protein interaction using its multivalency property.
Anand K. Agrahari, Sunil Kumar, Anindra Sharma, Vinod K. Tiwari   +3 more
doaj   +1 more source

Click Chemistry in Materials Science [PDF]

, 2014
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/106803/1/adfm201302847 ...
Bowman, Christopher N., Kloxin, Christopher J., Scott, Timothy F., Xi, Weixian   +3 more
core   +1 more source

Peptoids and polyamines going sweet: Modular synthesis of glycosylated peptoids and polyamines using click chemistry

Beilstein Journal of Organic Chemistry, 2013
Sugar moieties are present in a wide range of bioactive molecules. Thus, having versatile and fast methods for the decoration of biomimetic molecules with sugars is of fundamental importance.
Daniel Fürniss, Timo Mack, Frank Hahn, Sidonie B. L. Vollrath, Katarzyna Koroniak, Ute Schepers, Stefan Bräse   +6 more
doaj   +1 more source

Noncanonical Amino Acids in the Interrogation of Cellular Protein Synthesis [PDF]

, 2011
Proteins in living cells can be made receptive to bioorthogonal chemistries through metabolic labeling with appropriately designed noncanonical amino acids (ncAAs).
Ngo, John T., Tirrell, David A.
core   +2 more sources

Site-Specific Fluorogenic Protein Labelling Agent for Bioconjugation

Biomolecules, 2020
Many clinically relevant therapeutic agents are formed from the conjugation of small molecules to biomolecules through conjugating linkers. In this study, two novel conjugating linkers were prepared, comprising a central coumarin core, functionalized ...
Kelvin K. Tsao, Ann C. Lee, Karl É. Racine, Jeffrey W. Keillor   +3 more
doaj   +1 more source

N-[7-Chloro-4-[4-(phenoxymethyl)-1H-1,2,3-triazol-1-yl]quinoline]-acetamide

Molbank, 2021
The 1,2,3-triazole is a well-known biologically active pharmacophore constructed by the copper-catalyzed azide–alkyne cycloaddition. We herein reported the synthesis of 4-amino-7-chloro-based [1,2,3]-triazole hybrids via Cu(I)-catalyzed Huisgen 1,3 ...
Paolo Coghi, Jerome P. L. Ng, Ali Adnan Nasim, Vincent Kam Wai Wong   +3 more
doaj   +1 more source

Evaluation of bicinchoninic acid as a ligand for copper(I)-catalyzed azide-alkyne bioconjugations [PDF]

, 2012
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG geförderten) Allianz- bzw. Nationallizenz frei zugänglich.This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence
Budisa, Nediljko, Christen, Erik H., Fussenegger, Martin, Gübeli, Raphael J., Kaufmann, Beate, Merkel, Lars, Schoenmakers, Ronald, Weber, Wilfried, Wiltschi, Birgit   +8 more
core   +1 more source

Core-Clickable PEG-Branch-Azide Bivalent-Bottle-Brush Polymers by ROMP: Grafting-Through and Clicking-To [PDF]

, 2011
The combination of highly efficient polymerizations with modular "click" coupling reactions has enabled the synthesis of a wide variety of novel nanoscopic tructures.
Burts, Alan O., Finn, M. G., Grubbs, Robert H., Johnson, Jeremiah A., Koberstein, Jeffrey T., Lim, Yeon-Hee, Lu, Ying Y., Tirrell, David A., Turro, Nicholas J.   +8 more
core   +2 more sources

Covalent Attachment of Aggregation-Induced Emission Molecules to the Surface of Ultrasmall Gold Nanoparticles to Enhance Cell Penetration

Molecules, 2022
Three different alkyne-terminated aggregation-induced emission molecules based on a para-substituted di-thioether were attached to the surface of ultrasmall gold nanoparticles (2 nm) by copper-catalyzed azide–alkyne cycloaddition (click chemistry).
Kai Klein, Matthias Hayduk, Sebastian Kollenda, Marco Schmiedtchen, Jens Voskuhl, Matthias Epple   +5 more
doaj   +1 more source