Results 251 to 260 of about 227,350 (349)

A method for site-specifically tethering the enzyme urease to DNA origami with sustained activity. [PDF]

open access: yesPLoS One
Murphy I   +8 more
europepmc   +1 more source

Conditional Activation of Protein Therapeutics by Templated Removal of Peptide Nucleic Acid Masking Groups

open access: yesAngewandte Chemie, EarlyView.
A strategy for the conditional activation of therapeutic proteins utilizing removable peptide nucleic acid (PNA) masking groups is presented. Site‐specific installation of “Lock”‐PNAs containing a cleavage thioester linkage enabled steric blockage of receptor binding sites.
Bengt H. Gless   +6 more
wiley   +1 more source

Remote Silyl Groups Enhance Hydrolytic Stability and Photocleavage Efficiency in Carbamates for Protein Release

open access: yesAngewandte Chemie, EarlyView.
Introducing remote silyl groups into coumarin derivatives enhances their hydrolytic stability and photocleavage efficiency. This innovative molecular design enables efficient protein release from solid phase material upon photo irradiation, advancing applications in chemical biology and photomanipulation.
Masahiko Yoshimura   +5 more
wiley   +1 more source

In situ UNIversal Orthogonal Network (UNION) bioink deposition for direct delivery of corneal stromal stem cells to corneal wounds. [PDF]

open access: yesBioact Mater
Brunel LG   +9 more
europepmc   +1 more source

Oxidation of Azide by Peroxodisulf ate in Aqueous Medium [PDF]

open access: bronze, 1978
V. Ponnuraj   +3 more
openalex   +1 more source

Konvergenter Aufbau Homo‐ und Heterotypischer Ubiquitinketten aus funktionaliserten, exprimierten Monomeren mittels Thiol‐En‐Chemie

open access: yesAngewandte Chemie, EarlyView.
Die Erzeugung funktionalisierter Ubiquitinbausteine mittels Expression in E. coli bietet Zugang zu verschiedenen Di‐, Tri‐ und Tetra‐Ubiquitinketten. Photoinitiierte Thiol‐En‐Klickreaktionen werden dabei in Kombination mit einer Maskierungs‐ und Schutzgruppenstrategie zum kontrollierten Aufbau von Ubiquitinketten sowie zur Semisynthese von ...
Moritz Urschbach   +6 more
wiley   +1 more source

A Modular Customizable Ligand-Conjugate (LC) System Targeting Ghrelin <i>O</i>-Acyltransferase. [PDF]

open access: yesBiomolecules
Ford AL   +7 more
europepmc   +1 more source

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