Copper(I)-Phosphinite Complexes in Click Cycloadditions: Three-Component Reactions and Preparation of 5-Iodotriazoles [PDF]
, 2016 © 2016 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA.The remarkable activity displayed by copper(I)–phosphinite complexes of general formula [CuBr(L)] in two challenging cycloadditions is reported: a) the one-pot azidonation/cycloaddition of
Crosbie, P +3 more
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Regioselective and stoichiometrically controlled conjugation of photodynamic sensitizers to a HER2 targeting antibody fragment [PDF]
, 2014 The rapidly increasing interest in the synthesis of antibody–drug conjugates as powerful targeted anticancer agents demonstrates the growing appreciation of the power of antibodies and antibody fragments as highly selective targeting moieties.
Boyle, Ross W. +6 more
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End-group functionalization of poly(2-oxazoline)s using methyl bromoacetate as initiator followed by direct amidation [PDF]
, 2019 Poly(2-alkyl/aryl-2-oxazoline)s (PAOx) are an alluring class of polymers for many applications due to the broad chemical diversity that is accessible for these polymers by simply changing the initiator, terminating agent and the monomer(s) used in their ...
Arys, Koen +4 more
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Designed Monomers and Polymers, 2019 Current solid rocket propellant formulations still employ traditional ingredients utilized since the 1960s, such as hydroxyl terminated polybutadiene (HTPB).
Tianze Cheng
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Isolation of bis(copper) key intermediates in Cu-catalyzed azide-alkyne "click reaction". [PDF]
, 2015 The copper-catalyzed 1,3-dipolar cycloaddition of an azide to a terminal alkyne (CuAAC) is one of the most popular chemical transformations, with applications ranging from material to life sciences.
Bertrand, Guy +3 more
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Chemoselectivity of Tertiary Azides in Strain‐Promoted Alkyne‐Azide Cycloadditions [PDF]
Chemistry – A European Journal, 2018 AbstractThe strain‐promoted alkyne‐azide cycloaddition (SPAAC) is the most commonly employed bioorthogonal reaction with applications in a broad range of fields. Over the years, several different cyclooctyne derivatives have been developed and investigated in regard to their reactivity in SPAAC reactions with azides.
Hannes Mikula +6 more
openaire +6 more sources
A cell-permeable biscyclooctyne as a novel probe for the identification of protein sulfenic acids [PDF]
, 2016 Reactive oxygen species act as important second messengers in cell signaling and homeostasis through the oxidation of protein thiols. However, the dynamic nature of protein oxidation and the lack of sensitivity of existing molecular probes have hindered ...
Hartley, Richard C. +4 more
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SynOpen, 2018 Despite the widespread applications of various rhodamine and fluorescein 5- and 6-carboxy derivatives, the preparation of their pure regioisomers, in particular cases, remains a complex task.
Nadezhda S. Baleeva +2 more
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Advanced Functional Materials, EarlyView.In this work, a magnetic core‐shell catalyst (HOF‐on‐Fe3O4/ZIF‐67) is successfully synthesized, consisting of a metal–organic framework (ZIF‐67) with magnetic Fe3O4 as the core and a porous hydrogen‐bonded organic framework (HOF) as the shell. The catalyst efficiently activated peroxymonosulfate, resulting in rapid and effective removal of water ...
Yingying Du +4 more
wiley +1 more source
Advancements in the mechanistic understanding of the copper-catalyzed azide–alkyne cycloaddition
Beilstein Journal of Organic Chemistry, 2013 The copper-catalyzed azide–alkyne cycloaddition (CuAAC) is one of the most broadly applicable and easy-to-handle reactions in the arsenal of organic chemistry.
Regina Berg, Bernd F. Straub
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