Results 31 to 40 of about 129,557 (307)

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Well-Defined Diimine Copper(I) Complexes as Catalysts in Click Azide-Alkyne Cycloaddition Reactions

Molecules, 2013
A series of 1,4-disubstituted 1,2,3-triazoles have been prepared in high yields while respecting the stringent Click criteria. In these reactions, highly stable pre-formed complexes bearing diimine ligands were used.
Silvia Díez-González, Jordi Markalain Barta   +1 more
doaj   +1 more source

Coexistence of Spin Canting and Metamagnetism in a One-Dimensional Mn(II) Compound Bridged by Alternating Double End-to-End and Double End-On Azido Ligands and the Analog Co(II) Compound

Magnetochemistry, 2021
Two new compounds of general formula [M(N3)2(dmbpy)] in which dmbpy = 5,5′-dimethyl-2,2′-bipyridine, and M = Mn(II) or Co(II), have been solvothermally synthesized and characterized structurally and magnetically.
Nesrine Benamara, Zouaoui Setifi, Chen-I Yang, Sylvain Bernès, David K. Geiger, Güneş Süheyla Kürkçüoğlu, Fatima Setifi, Jan Reedijk   +7 more
doaj   +1 more source

LIN28B Promotes Cancer Cell Dissemination and Angiogenesis

Advanced Biology, EarlyView.
Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo, Sara Menegazzo, Marcella Pantile, Silvia Bresolin, Carlo Zanon, Alessandro Davini, Massimiliano Mazzone, Alessandra Biffi, Sanja Aveic   +8 more
wiley   +1 more source

[(2-Chlorophenyl)-(4-fluorophenyl)methylene]-(4-fluorophenyl)amine

Molbank
The formation of a N,1,1-triaryl imine derived from (2-chlorophenyl)-bis-(4-fluorophenyl)methanol is reported. The title compound is formed from a consecutive process which involves a nucleophilic substitution and subsequent Schmidt reaction.
Salvador Vilchis-Valdés, Alberto Cedillo-Cruz, Marco A. García-Eleno, Diego Martínez-Otero, Erick Cuevas-Yañez   +4 more
doaj   +1 more source

Electrochemical vicinal oxyazidation of α-arylvinyl acetates

Beilstein Journal of Organic Chemistry, 2022
α-Azidoketones are valuable and versatile building blocks in the synthesis of various bioactive small molecules. Herein, we describe an environmentally friendly and efficient electrochemical vicinal oxyazidation protocol of α-arylvinyl acetates to afford
Yi-Lun Li, Zhaojiang Shi, Tao Shen, Ke-Yin Ye   +3 more
doaj   +1 more source

s-Triazine: A Privileged Structure for Drug Discovery and Bioconjugation

Molecules, 2021
This review provides an overview of the broad applicability of s-triazine. Our many years working with this intriguing moiety allow us to discuss its wide activity spectrum (inhibition against MAO-A and -B, anticancer/antiproliferative and antimicrobial ...
Anamika Sharma, Rotimi Sheyi, Beatriz G. de la Torre, Ayman El-Faham, Fernando Albericio   +4 more
doaj   +1 more source

In Situ Constructed Magnetic Core‐Shell Hydrogen‐Bonded Organic Framework‐on‐Metal–Organic Framework Structure: an Efficient Catalyst for Peroxymonosulfate Activation

Advanced Functional Materials, EarlyView.
In this work, a magnetic core‐shell catalyst (HOF‐on‐Fe3O4/ZIF‐67) is successfully synthesized, consisting of a metal–organic framework (ZIF‐67) with magnetic Fe3O4 as the core and a porous hydrogen‐bonded organic framework (HOF) as the shell. The catalyst efficiently activated peroxymonosulfate, resulting in rapid and effective removal of water ...
Yingying Du, Chenhui Ding, Chao Deng, Susanta Banerjee, Seema Agarwal   +4 more
wiley   +1 more source

Salivary Hydrogen Sulfide Measured with a New Highly Sensitive Self-Immolative Coumarin-Based Fluorescent Probe

Molecules, 2018
Ample evidence suggests that H2S is an important biological mediator, produced by endogenous enzymes and microbiota. So far, several techniques including colorimetric methods, electrochemical analysis and sulfide precipitation have been developed for H2S
Ewelina Zaorska, Marek Konop, Ryszard Ostaszewski, Dominik Koszelewski, Marcin Ufnal   +4 more
doaj   +1 more source

Five-Coordinated Geometries from Molecular Structures to Solutions in Copper(II) Complexes Generated from Polydentate-N-Donor Ligands and Pseudohalides

Molecules, 2020
A novel series of mononuclear five-coordinated pseudohalido-Cu(II) complexes displaying distorted square bipyramidal: [Cu(L1)(NCS)2] (1), [Cu(L2)(NCS)2] (2) and [Cu(L3)(NCS)]ClO4 (5) as well as distorted trigonal bipyramidal: [Cu(isp3tren)(N3)]ClO4 (3), [
Franz A. Mautner, Roland C. Fischer, Ana Torvisco, Maher M. Henary, Febee R. Louka, Salah S. Massoud, Nahed M. H. Salem   +6 more
doaj   +1 more source