Results 121 to 130 of about 25,600 (309)

Calcitonin Gene‐Related Peptide (CGRP)‐Expressing Neurons in the External Lateral Parabrachial Area Regulate Pain‐Induced Sleep Disturbances

Advanced Science, EarlyView.
Lynch et al., identified novel targets on the wake‐promoting pathways that can effectively treat pain‐induced sleep disturbances. The authors demonstrated that Calcitonin gene‐related peptide‐expressing neurons (CGRP) in the external lateral parabrachial nucleus (PBelCGRP) serve as the primary relay node for pain stimuli that cause sleep disruption ...
Nicole Lynch, Roberto De Luca, Richard L Spinieli, Enrico Rillosi, Renner C Thomas, Samuel Sailesh, Nishta Gangeddula, Janayna D Lima, Sathyajit S Bandaru, Elda Arrigoni, Agustin Melo‐Carrillo, Rami Burstein, Stephen Thankachan, Satvinder Kaur   +13 more
wiley   +1 more source

Remodeling the Physicochemical and Pharmacokinetic Properties of PROTAC via Lipid Nanodisks for Cancer Therapy

Advanced Science, EarlyView.
To solve the challenge of PROTACs in clinical potential due to poor water solubility and membrane permeability, a nanodelivery system based on lipid nanodisks loaded with MZ1 prodrug (LND‐MZ1) to remodel the physicochemical and pharmacokinetic properties of PROTAC MZ1 is elaborately proposed.
Meichen Pan, Chunrong Yang, Zhongliang Fu, Yuchen Yang, Ying Zhuo, Hongwei Hou, Jinghong Li   +6 more
wiley   +1 more source

Iron Oxide Nanoparticles Modified with Galloylated DNA for Magnetically Enhanced DNA‐Directed Assembly

Advanced Science, EarlyView.
A simple one‐step method is presented for DNA functionalization of iron oxide nanoparticles (IONP) using multidentate galloylated DNA. The DNA‐modified IONPs exhibit unique DNA binding properties of magnetically enhanced DNA interconnects. This study underscores the importance of nanoparticle (NP) effects in DNA sequence design and highlights the ...
Murali Golla, Hyunjin Jeon, Shine K. Albert, Hojun Lee, Seulki Kang, Moon Jeong Park, So‐Jung Park   +6 more
wiley   +1 more source

Determination of Azide Ion by Hydrogen Ion Titration after Oxidation with Nitrite. [PDF]

, 1965
Ray G. Clem, E. H. Huffman
openalex   +1 more source

ε‐Poly‐L‐lysine‐graft‐oligo(3‐hexylthiophene) Copolymers as Antibacterial and Biodegradable Polymer Electronics

Advanced Science, EarlyView.
ε‐Poly‐L‐lysine‐graft‐oligo(3‐hexylthiophene) (EPL‐g‐O3HT) copolymers are engineered as biodegradable and antibacterial materials for transient electronics. EPL‐g‐O3HT exhibits tunable conductivity, controlled enzymatic degradability, good biocompatibility, and potent antibacterial activity. They are demonstrated in electromyography sensors and organic
Xin Sun, Eddie Wai Chi Chan, Fathumma Rizana Shiraz, Bicheng Zhu, Jingwen Yang, Katharina Matura, Viji Sarojini, Serpil Tekoglu, David Barker, Jadranka Travas‐Sejdic   +9 more
wiley   +1 more source

Preparation and Growth of Single Crystals of Metallic Azides by Controlled Diffusion in Silica Gel System [PDF]

, 1969
D. K. Ranadive, Z. Blank, Walter Brenner, Yoshiyuki Okamoto   +3 more
openalex   +1 more source

Properties of azide-catalase [PDF]

Biochemical Journal, 1945
E. F. Hartree, David Keilin
openaire   +3 more sources

FLASH Irradiation Modulates Immune Responses and Accelerates Lung Recovery: A Single‐Cell Perspective

Advanced Science, EarlyView.
Single‐cell RNA sequencing reveals distinct immune responses to FLASH versus conventional dose rate irradiation in early radiation‐induced lung injury. FLASH irradiation reduces Ccrl2⁺ neutrophil infiltration, activates CD4⁺ CD40L⁺ Th cells, restrains pro‐inflammatory Mefv⁺ monocytes, and enhances epithelial repair via TGF‐β signaling, underscoring its
Hao Lu, Menghua Li, Cheng Quan, Caihui Li, Dawei Li, Zhihui Li, Jing Xu, Lihui Zhang, Qixiang Liu, Guofu Dong, Changzhen Wang   +10 more
wiley   +1 more source

THE PHOTOCHEMICAL DECOMPOSITION OF SODIUM AZIDE [PDF]

, 1966
P. W. M. Jacobs, A. R. Tariq Kureishy
openalex   +1 more source

Hydrocyclization/Defluorination of CF3‐Substituted Acrylamides: Insights from Kinetics of Hydrogen Atom Transfer

Advanced Science, EarlyView.
The study develops a H•/H– transfer strategy enabling efficient hydrocyclization/defluorination of CF3‐acrylamides to synthesize Seletracetam derivatives with gem‐difluoroalkenes. Mechanistic studies reveal distinct pathways: the NiII‐H/PhSiH3 system operates through a hydrogen atom transfer process, while the 1,4‐Michael addition of H– appears to be ...
Yanjun Wan, Ronghui Shao, Jack R. Norton
wiley   +1 more source