Results 121 to 130 of about 9,162 (234)

Trisoxazole Macrolides Potentiate the Microtubule Assembly and Antimitotic Activities of Taxanes

open access: yesAngewandte Chemie, EarlyView.
Photoaffinity experiments identified tubulin as a new target of mycalolides. Though weakly cytotoxic, the trisoxazole macrolactone moiety enhanced paclitaxel's microtubule assembly and antimitotic effects. Molecular modeling studies suggested that MyC stabilizes α/β‐tubulin heterodimer interactions.
Shohei Ebihara   +4 more
wiley   +2 more sources

Selective Chiral Diamine-bisoxazoline Iron(II) Catalysts for Pyrrolidine Formation via Intramolecular C(sp<sup>3</sup>)-H Amination of Aliphatic Azides. [PDF]

open access: yesJ Am Chem Soc
He Z   +9 more
europepmc   +1 more source

Domino Polymerization for the Synthesis of Reductively Degradable Poly(disulfide)s With Arbitrary Side‐Chain Structures

open access: yesAngewandte Chemie, EarlyView.
We developed a novel domino polymerization to synthesize reductively degradable poly(disulfide)s with tunable side chains. A novel monomer bearing thiolactone and pyridyl disulfide groups reacts with various amines, enabling continuous ring‐opening and disulfide exchange.
Yukiya Kitayama   +2 more
wiley   +2 more sources

Crystals as Rockets: Modulation of the Salient Temperature in Cocrystals by Solvent Mixture Composition

open access: yesAngewandte Chemie, EarlyView.
Compositionally engineered mixed solvated cocrystals enable modulation of thermosalient actuation. Guest ratio controls thermosalient temperature and propulsion intensity, providing a tunable platform for designing crystalline systems that exhibit stimuli‐responsive mechanical motion.
Ernesto A. Hernández‐Morales   +5 more
wiley   +2 more sources

Phenylpyridine-Based Boron Azides: Tuning Reactivity and Accessing Fluorescent Triazoles. [PDF]

open access: yesInorg Chem
Škoch K   +7 more
europepmc   +1 more source

Wash‐Free Multi‐Target Super‐Resolution Microscopy With Photocaged DNA Labels

open access: yesAngewandte Chemie, EarlyView.
Photocaged DNA labels enable wash‐free multi‐target super‐resolution microscopy. A single type of DNA–fluorophore imager strand hybridizes to two orthogonal light‐responsive docking strands, whose hybridization state can be modulated with light from “ON” to “OFF” and vice versa.
Nina Kaltenschnee   +6 more
wiley   +2 more sources

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