Results 181 to 190 of about 43,569 (363)
Advanced Science, EarlyView.It is shown that obesity is associated with increases in hepatic METTL14 and m6A methylation of G6pc transcript. YTHDF1 and YTHDF3 bind to m6A‐marked G6pc mRNA to increase its synthesis. Hepatocyte‐specific deletion of Mettl14 decreases G6pc m6A methylation, G6pc biosynthesis, and G6pc‐mediated gluconeogenesis, alleviating glucose metabolic defects in ...
Qiantao Zheng +6 more
wiley +1 more source
The reactions of azide with catalase and their significance [PDF]
, 1964 Peter Nicholls
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Advanced Science, EarlyView.A CTGF‐LYTAC nanoplatform is developed to selectively degrade connective tissue growth factor (CTGF) in triple‐negative breast cancer (TNBC), inhibiting TGF‐β signaling and cell interactions in the tumor microenvironment (TME). This strategy effectively suppresses tumor growth and metastasis, outperforming antibody‐based therapy.
Jia‐Yi Lin +11 more
wiley +1 more source
Isolation and Characterization of the Cyanide-Resistant and Azide-Resistant Catalase of Lactobacillus plantarum [PDF]
, 1965 M. Andrew Johnston, E. A. Delwiche
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Design, Synthesis, and Application of Immobilized Enzymes on Artificial Porous Materials
Advanced Science, EarlyView.This review comprehensively summarizes the advances in research for immobilized enzymes on artificial porous materials. It highlights the advantages of bottom‐up strategy, post‐synthesis modification and composite method of metal‐organic frameworks (MOFs), covalent organic frameworks (COFs) and hydrogen‐bonded organic frameworks (HOFs) and emphasizes ...
Lu Ran +4 more
wiley +1 more source
Suspended Tissue Open Microfluidic Patterning (STOMP)
Advanced Science, EarlyView.Suspended Tissue Open Microfluidic Patterning (STOMP) is a method that enables precise spatial patterning within a single suspended tissue. By leveraging capillary pinning and open microfluidics, STOMP facilitates the creation of complex tissue interfaces such as diseased‐healthy boundaries and tissue‐tissue junctions. This method integrates mechanical
Amanda J. Haack +22 more
wiley +1 more source
Adsorption of Cadmium(II) and Zinc(II) on Mercury Induced by Azide Anions [PDF]
, 1969 Zygmunt Kowalski, Fred C. Anson
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Properties of azide-catalase [PDF]
Biochemical Journal, 1945 E. F. Hartree, David Keilin
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Advanced Science, EarlyView.The study develops a H•/H– transfer strategy enabling efficient hydrocyclization/defluorination of CF3‐acrylamides to synthesize Seletracetam derivatives with gem‐difluoroalkenes. Mechanistic studies reveal distinct pathways: the NiII‐H/PhSiH3 system operates through a hydrogen atom transfer process, while the 1,4‐Michael addition of H– appears to be ...
Yanjun Wan, Ronghui Shao, Jack R. Norton
wiley +1 more source
Evidence for the formation of exo and endo aziridines in the reaction of cis–endo and cis–exo-bicyclo[2•2•1]-5-heptene-2,3-dicarboxylic anhydride and benzenesulfonyl azide [PDF]
, 1969 A. C. Oehlschlager, L. H. Zalkow
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