Results 211 to 220 of about 25,600 (309)

Asymmetric Aziridination of Allylic Carbamates Using Ion‐Paired Rhodium Complexes and Extrapolation to C─H Amination of Phenethyl Carbamates

open access: yesAngewandte Chemie, EarlyView.
Aziridination of alkenes is an important route to chiral nitrogen‐containing building blocks. We report that carbamate‐functionalized allylic alcohols undergo highly enantioselective aziridination using achiral dimeric Rh complexes ion‐paired with cinchona alkaloid‐derived chiral cations.
Arthur R. Lit   +4 more
wiley   +1 more source

Staudinger Reaction-Responsive Coacervates for Cytosolic Antibody Delivery and TRIM21-Mediated Protein Degradation. [PDF]

open access: yesJ Am Chem Soc
Bao Y   +10 more
europepmc   +1 more source

Peptide‐Carbazolyl Cyanobenzene Conjugates: Enabling Biomolecule Functionalization via Photoredox and Energy Transfer Catalysis

open access: yesAngewandte Chemie, EarlyView.
We introduce two methods for incorporating carbazolyl cyanobenzenes onto peptides: a C‐terminus decarboxylative functionalization and a Cys‐selective SNAr reaction. Both conjugates exhibit excellent photoredox/energy‐transfer properties, enabling their use for C‐terminal alkynylation and Cys‐selective thiol‐ene reactions on peptides, as well as ...
Xing‐Yu Liu   +4 more
wiley   +1 more source

Controlling Assembly of Hybrid DNA Nanostructures into Higher‐Order Structures via Hydrophobicity

open access: yesAngewandte Chemie, EarlyView.
We harness hydrophobic interactions, fundamental in biology yet underutilized in DNA nanotechnology, to build a design framework for hierarchical DNA assemblies. By conjugating small hydrophobic molecules to DNA motifs, we controlled the formation of higher‐order structures, moving beyond traditional Watson–Crick pairing.
Minu Saji   +4 more
wiley   +1 more source

Total Synthesis of Isodaphlongamine H by Iridium‐Catalyzed Reductive [3 + 2] Cycloaddition of N‐Hydroxylactam

open access: yesAngewandte Chemie, EarlyView.
The total synthesis of isodaphlongamine H was accomplished by a lactam strategy. This strategy started with alkylation and N‐oxidation of a readily available chiral lactam. For the key functionalization of the amide carbonyl, an iridium‐catalyzed reductive [3 + 2] cycloaddition of the N‐hydroxylactam afforded the tricyclic isoxazolidine, which was ...
Sora Iwamoto   +15 more
wiley   +1 more source

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