Results 211 to 220 of about 43,569 (363)

Stability and Mitochondrial Localization of a Highly Cytotoxic Organogold(III) Complex with Diphosphine Ancillary Ligand in Lung Cancer Cells

open access: yesAngewandte Chemie, EarlyView.
The combination of cryo‐synchrotron radiation‐X‐ray fluorescence (cryo‐SR‐XRF), cryo‐synchrotron radiation‐X‐ray absorption (cryo‐SR‐XAS) and high‐resolution mass spectrometry demonstrates the high intracellular stability of a biphenyl gold(III) diphosphine complex indicating the native organogold cation as the active species.
Hester Blommaert   +10 more
wiley   +2 more sources

Access to Carbonyl Azides via Iodine(III)-Mediated Cross-Coupling. [PDF]

open access: yesOrg Lett
Yan Q   +7 more
europepmc   +1 more source

Manipulation of Chemistry and Biology with Visible Light Using Tetra‐ortho‐Substituted Azobenzenes and Azonium Ions

open access: yesAngewandte Chemie, EarlyView.
Tetra‐ortho‐Azobenzenes (TOABs) in broad daylight: in recent years, TOAB photoswitches became indispensable tools for all‐visible‐light manipulation of chemistry, biology and materials. This review explores their unique photochemical properties, design and synthetic approaches, offering support in choosing a TOAB for a given application.
Francesca Cardano   +2 more
wiley   +2 more sources

Synthesis and Characterization of Photoswitchable Covalent Ligands for the β2‐Adrenoceptor

open access: yesAngewandte Chemie, EarlyView.
A structure‐based design of a covalent photoswitchable ligand for the β2‐adrenergic receptor, a therapeutically relevant GPCR, is described. This tool facilitates the modification of the intrinsic activity of the protein by light. Computational analysis of its mechanism of action suggests that the photoswitch takes place within the binding pocket ...
Ulrike Wirth   +9 more
wiley   +2 more sources

Indirect Anti‐Markovnikov Hydrofunctionalization of Terminal Alkenes via an Alkenyl Thianthrenium Intermediate

open access: yesAngewandte Chemie, EarlyView.
A two‐stage dication pool strategy using alkenyl thianthrenium intermediates has been developed for anti‐Markovnikov hydrofunctionalization. This method differs from previous approaches in its reaction mechanism and addresses their most significant limitation, namely, the restricted generality of the nucleophile. The approach has been extended to other
Bence Sóvári   +7 more
wiley   +2 more sources

Home - About - Disclaimer - Privacy