Results 221 to 230 of about 25,600 (309)

Is a Malleable Active Site Loop the Key to High Substrate Promiscuity? Hybrid, Biocatalytic Route to Structurally Diverse Taxoid Side Chains with Remarkable Dual Stereocontrol

open access: yesAngewandte Chemie, EarlyView.
A highly stereoselective, dynamic reductive kinetic resolution (DYRKR) entry into myriad Taxotere‐like side chains with Clostridium acetobutylicum alcohol dehydrogenase (CaADH) enzyme is reported. Follow‐on cross couplings expand the structural diversity of the library (36 total examples).
Gaurav P. Kudalkar   +15 more
wiley   +1 more source

Reductive N2 Cleavage and Nitride Insertion Reactivity at Molybdenum Complexes Supported by a Rigid PNP Pincer

open access: yesAngewandte Chemie, EarlyView.
Reductive N2 cleavage at an acridane PNP pincer‐supported Mo center leads to the first crystallographically characterized example of an unusual Mo(IV) nitride species featuring a bridging N2 coordination stabilized via Mo‐N2 dπ‐pπ backbonding interactions. Nitride functionalization with CO leads to Mo(II) isocyanate species.
Minjun Kim   +8 more
wiley   +1 more source

Red‐Light‐Mediated Generation of Radicals: Applications in Organic Synthesis, Small‐Molecule Activation, Polymerization, and Bio‐Related Fields

open access: yesAngewandte Chemie International Edition, EarlyView.
Visible light‐driven photochemistry has advanced significantly, offering diverse methodologies in synthetic organic chemistry. Photocatalysis using red and near‐infrared (NIR) light is particularly notable due to its lower energy, reduced phototoxicity, minimized side reactions, and deeper penetration into reaction media.
Tong Zhang, Suman Pradhan, Shoubhik Das
wiley   +1 more source

Microscale Tattooing of Hydrogels and Cells: Benzoxaborole‐Driven Microcontact Printing (µCP) on Glycosylated Surfaces

open access: yesAngewandte Chemie International Edition, Accepted Article.
Microcontact printing (µCP) is a widely used technique for microscale surface patterning. In this study, we present a polymer‐supported µCP method for the patterning of (bioactive) glycosylated surfaces under hydrated conditions. Patterning is achieved by direct contact with a grooved polydimethylsiloxane (PDMS) stamp, whose surface was grafted with a ...
Nazim Pallab   +8 more
wiley   +1 more source

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