Results 101 to 110 of about 7,765 (231)
Role of Reversible Dimerization in Reactions of Amphoteric Aziridine Aldehydes
, 2016 Unprotected aziridine aldehydes belong to the amphoteric class of molecules by virtue of their dual nucleophilicity/electrophilicity. The dimeric nature of these molecules, brought together by a weak and reversible aminal “connection”, was found to be an
Takahito Kasahara (1702036) +6 more
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Small Nitrogen Heterocycles Containing 1,2,3-Triazoles in the Side Chain
New libraries of aziridine and azetidine derivatives containing 1,4-disubstituted 1,2,3-triazole in the side chain as well as aziridine derivatives containing 1,5-disubstituted 1,2,3-triazole in the side chain were synthesized by transition metals ...
Suta, Krista +2 more
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Studies on Substituted Aziridine-Boranes
, 1971 2-Methylaziridine—borane, 1,2-dimethylaziridine-borane, 2,2-dimethylaziridine-borane, N-ethylaziridine-borane, 2-ethyl- aziridine-borane, and 2~phenylaziridine-borane have been prepared for the first time.
Lee, Jae
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Synthetic Applications of N-H Aziridine Containing Compounds
, 2010 Unprotected N-H aziridine aldehydes are surprisingly stable compounds which can undergo reactions in the absence of protecting groups. In total, three different transformations were explored during my Master’s thesis.
Decker, Shannon Marie
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A Linchpin Synthesis of 6‑Hydroxyceramides from Aziridine Aldehydes
, 2016 A chemoselective N-oxidation/Meisenheimer rearrangement protocol was developed to generate vinylaziridine scaffolds from aziridine aldehydes. A subsequent Lewis acid-mediated aziridine ring opening with carboxylic acid nucleophiles followed by N–O bond ...
Sean. K. Liew (3365432) +2 more
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Secondary 3‐Chloropiperidines: Powerful Alkylating Agents
ChemistryOpenIn previous works, we demonstrated that tertiary 3‐chloropiperidines are potent chemotherapeutics, alkylating the DNA through the formation of bicyclic aziridinium ions. Herein, we report the synthesis of novel secondary 3‐chloropiperidine analogues. The
Mats Georg +5 more
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Chemically accurate conformational energies for aziridine-2-carbonitrile
, 2001 The energy of trans-aziridine-2-carbonitrile relative to cis-aziridine-2-carbonitrile was determined by carrying out extensive ab initio computations.
Gregory S. Tschumper +1 more
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A Facile Synthesis of Amino Acid Derivatives from Aziridines in Liquid Sulfur Dioxide
In the past decades aziridines have played a role of versatile intermediates and important precursors for the synthesis of nitrogencontaining biologically active compounds. Modification of aziridine cycle leads to formation of agents of different classes,
Lugiņina, Jevgeņija, Turks, Māris
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Recent progress in asymmetric synthesis of aziridine derivatives (microreview)
, 2018 This microreview describes recent advances in asymmetric synthesis of aziridine derivatives, which have been published over the last two ...
Doğan, Özdemir, Polat-Cakir, Sidika
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Ring-Opening Reactions of the N‑4-Nosyl Hough–Richardson Aziridine with Nitrogen Nucleophiles
, 2016 Dinosylated α-d-glucopyranoside was directly transformed into α-d-altropyranosides via in situ formed N-4-nosyl Hough–Richardson aziridine with nitrogen nucleophiles under mild conditions in fair to excellent yields.
Tomáš Ručil (3388715) +2 more
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