Results 91 to 100 of about 72,034 (334)
mBio, 2019 Fungal pathogens pose a serious threat to public health. Candida auris is an emerging fungal pathogen that is often resistant to commonly used antifungal drugs.
Sang Hu Kim +7 more
semanticscholar +1 more source
Antimicrobial Agents and Chemotherapy, 2020 The limited therapeutic options and the recent emergence of multidrug-resistant Candida species present a significant challenge to human medicine and underscore the need for novel therapeutic approaches.
Hassan E. Eldesouky +4 more
semanticscholar +1 more source
Interfacial Photoelectrochemistry in Organic Synthesis
Angewandte Chemie International Edition, Accepted Article.Photoelectrodes have traditionally enjoyed widespread attention as heterogeneous catalysts for the activation of water and CO2 in energy research, while photoelectrochemistry with homogeneous molecular catalysts dominates the activations of more complex molecules in organic synthesis.
Gabriel Chan +4 more
wiley +1 more source
Epidemiological and genomic landscape of azole resistance mechanisms in Aspergillus fungi
Frontiers in Microbiology, 2016 Invasive aspergillosis is a life-threatening mycosis caused by the pathogenic fungus Aspergillus. The predominant causal species is Aspergillus fumigatus, and azole drugs are the treatment of choice.
Daisuke Hagiwara +3 more
doaj +1 more source
Nonrandom Distribution of Azole Resistance across the Global Population of Aspergillus fumigatus
mBio, 2019 Azole drug resistance in the human-pathogenic fungus Aspergillus fumigatus continues to emerge, potentially leading to untreatable aspergillosis in immunosuppressed hosts.
Thomas R. Sewell +6 more
semanticscholar +1 more source
Heliyon, 2019 ClIn(III) octacarboxy phthalocyanine (ClInOCPc) when alone or conjugated to magnetic nanoparticles (MNP-ClInOCPc) was employed for both photodynamic antimicrobial chemotherapy of an unknown water sample and Staphylococcus aureus, and for photo ...
Azole Sindelo, Tebello Nyokong
doaj
Ruthenium Catalyzed Ortho‐Arylation Reaction of Benzoic Acids with Arylthianthrenium Salts
Angewandte Chemie International Edition, EarlyView.A catalytic ortho‐arylation method has been developed to convert arylthianthrenium salts into carboxylate‐functionalized biaryls, which can be removed in situ or used for further derivatization. This reaction is broadly applicable to (hetero)arenecarboxylic acids, with excellent functional group compatibility and orthogonality to cross‐couplings ...
Kaiping Wang +9 more
wiley +1 more source
History of the development of azole derivatives [PDF]
Clinical Microbiology and Infection, 2004 Until the 1940s, relatively few agents were available for the treatment of systemic fungal infections. The development of the polyene antifungals represented a major advance in medical mycology. Although amphotericin B quickly became the mainstay of therapy for serious infections, its use was associated with infusion-related side-effects and dose ...
openaire +3 more sources
4-Amino-substituted Benzenesulfonamides as Inhibitors of Human Carbonic Anhydrases
Molecules, 2014 A series of N-aryl-β-alanine derivatives and diazobenzenesulfonamides containing aliphatic rings were designed, synthesized, and their binding to carbonic anhydrases (CA) I, II, VI, VII, XII, and XIII was studied by the fluorescent thermal shift assay ...
Kęstutis Rutkauskas +12 more
doaj +1 more source
Synergistic Anti-Candida Activity of Bengazole A in the Presence of Bengamide A †. [PDF]
, 2019 Bengazoles A⁻G from the marine sponge Jaspis sp. exhibit potent in vitro antifungal activity against Candida spp. and other pathogenic fungi. The mechanism of action (MOA) of bengazole A was explored in Candida albicans under both liquid culture and ...
Cheng, Tina +3 more
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