Results 111 to 120 of about 72,034 (334)
Molecular Detection of Azole-Resistant Aspergillus fumigatus in Clinical Samples
Frontiers in Microbiology, 2018 Aspergillus diseases are often caused by Aspergillus fumigatus. Azoles are the mainstay of therapy, but the management of aspergillosis is hampered by the emergence of azole resistance.
Jochem B. Buil +7 more
doaj +1 more source
The zinc cluster proteins Upc2 and Ecm22 promote filamentation in Saccharomyces cerevisiae by sterol biosynthesis-dependent and -independent pathways. [PDF]
, 2015 The transition between a unicellular yeast form to multicellular filaments is crucial for budding yeast foraging and the pathogenesis of many fungal pathogens such as Candida albicans.
Höfken, T, Woods, K
core +1 more source
ChemCatChem, EarlyView.A versatile modular strategy enables the synthesis of nickel nanoparticles functionalized with N‐heterocyclic carbene ligands and their subsequently immobilization onto graphene‐based supports. The hybrid catalytic material efficiently promotes the acceptorless dehydrogenation of alcohols, driven by synergistic effects between the metal–ligand ...
Judith Medina‐Vargas +4 more
wiley +1 more source
Role of isavuconazole in the treatment of invasive fungal infections
Therapeutics and Clinical Risk Management, 2016 Dustin T Wilson,1,2 V Paul Dimondi,1,3 Steven W Johnson,1,4 Travis M Jones,1 Richard H Drew1,5 1Department of Pharmacy Practice, Campbell University College of Pharmacy & Health Sciences, Buies Creek, NC, USA; 2Department of Pharmacy, Duke ...
Wilson DT +4 more
doaj
The Hsp90 co-chaperones Sti1, Aha1, and P23 regulate adaptive responses to antifungal azoles
Frontiers in Microbiology, 2016 Heat Shock Protein 90 (Hsp90) is essential for tumor progression in humans and drug resistance in fungi. However, the roles of its many co-chaperones in antifungal resistance are unknown. In this study, by susceptibility test of Neurospora crassa mutants
Xiaokui Gu +5 more
doaj +1 more source
Antimicrobial Agents and Chemotherapy, 2018 Multiple Erg11 amino acid substitutions were identified in clinical isolates of Candida auris originating from India and Colombia. Elevated azole MICs were detected in Saccharomyces cerevisiae upon heterologous expression of C.
K. Healey +6 more
semanticscholar +1 more source
A Cyp51B Mutation Contributes to Azole Resistance in Aspergillus fumigatus
Journal of Fungi, 2020 The emergence and spread of Aspergillus fumigatus azole resistance has been acknowledged worldwide. The main problem of azole resistance is the limited therapeutic options for patients suffering aspergillosis. Azole resistance mechanisms have been mostly
I. González-Jiménez +6 more
semanticscholar +1 more source
ChemMedChem, Accepted Article.Although great progresses have been accomplished in the field of antineoplastic treatments, the need for chemotherapy agents with new mechanisms of action remains essential. Metal complexes presenting hemilabile ligands could combine structural toxicity upon full coordination of the ligand and reactive toxicity upon ligand partial decoordination ...
Tom Lacoma +6 more
wiley +1 more source
Microbial assessment in a rare Norwegian book collection: a One Health approach to cultural heritage [PDF]
Microbial contamination poses a threat to both the preservation of library and archival collections and the health of staff and users. This study investigated the microbial communities and potential health risks associated with the UNESCO-classified Norwegian Sea Trade Archive (NSTA) collection exhibiting visible microbial colonization and staff health
arxiv +1 more source
, 2020 Septoria tritici blotch (STB; Zymoseptoria tritici ) is the most important leaf disease of wheat in Northern and Western Europe. The problem of fungicide resistance in Z. tritici populations is challenging future control options.
L. N. Jørgensen +20 more
semanticscholar +1 more source