Results 131 to 140 of about 57,959 (306)

Unveiling the Leishmanicidal Mechanism of 4‐Nerolidylcatechol Isolated From Piper peltatum Against Leishmania infantum

open access: yesChemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT The present study assessed the leishmanicidal activity of 4‐nerolidylcatechol (4‐NC) (1) isolated from Piper peltatum leaves against promastigotes and amastigotes of Leishmania amazonensis, L. braziliensis, and L. infantum. The plant was fractionated, leading to the isolation and chemical identification of 4‐NC (1). Biochemical techniques were
Fabiana Brusco Lorenzetti   +8 more
wiley   +1 more source

Caspofungin activity against clinical isolates of azole cross-resistant Candida glabrata overexpressing efflux pump genes [PDF]

open access: yes, 2017
Objectives: Several studies have documented the potent in vitro activity of caspofungin against Candida spp. This is of special concern for Candida glabrata infections that are often resistant to many azole antifungal agents and, consequently, difficult ...
Fadda, Giovanni   +6 more
core  

Candida auris in Heart Transplant Donor: First Isolation in a Southern Italy Heart Transplant Center

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
Timeline of infection control in a heart transplant from a donor colonized with Candida auris: from detection at retrieval to strict isolation, antifungal prophylaxis, negative follow‐up cultures, and successful prevention of transmission. ABSTRACT Candida auris is an emerging multidrug‐resistant fungal pathogen increasingly implicated in healthcare ...
Lorenzo Giovannico   +6 more
wiley   +1 more source

A Report on the Diagnosis and Treatment of Multiple Fungal Critical Brain Abscesses A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Multiple Candida glabrata (C. glabrata) brain abscesses are an exceptionally rare central‐nervous‐system infection. Clinical data on diagnosing and managing multiple Candida glabrata brain abscesses are still scarce. Here we reported a 66‐year‐old patient with multiple C. glabrata brain abscesses confirmed by cerebrospinal‐fluid puncture.
Chongyin Zhang   +4 more
wiley   +1 more source

[Azole-resistant invasive aspergillosis].

open access: yesNederlands tijdschrift voor geneeskunde, 2009
Contains fulltext : 79815.pdf (Publisher’s version ) (Open Access)
Linden, J.W.M. van der   +5 more
openaire   +3 more sources

Combinations of posaconazole and tacrolimus are effective against infections with azole-resistant Aspergillus fumigatus

open access: yesFrontiers in Cellular and Infection Microbiology
BackgroundSolid organ transplant recipients on immunosuppressants such as tacrolimus are at increased risk of developing pulmonary aspergillosis, a severe to deadly complication with limited treatment options, especially against azole-resistant strains ...
Eliane Vanhoffelen   +10 more
doaj   +1 more source

Population Pharmacokinetics to Support Intravenous and Enteral Methadone Dosing in Children

open access: yesThe Journal of Clinical Pharmacology, Volume 66, Issue 1, January 2026.
Abstract Methadone is used in hospitalized children to treat pain and iatrogenic opiate withdrawal. Optimal pediatric dosing for both enteral and intravenous methadone is unknown. We conducted two prospective, multi‐center, open‐label studies to characterize the pharmacokinetics of methadone in the pediatric population.
Kevin M. Watt   +15 more
wiley   +1 more source

Persistence of triazole fungicides in agricultural topsoil is driven by reduced bioaccessibility with aging

open access: yesJournal of Environmental Quality, Volume 55, Issue 1, January/February 2026.
Abstract Triazole fungicides are widely detected in agricultural soils, yet their long‐term persistence remains poorly understood. We evaluated how sorption, bioaccessibility, and degradation change with aging under field conditions. Topsoil was collected over 2 years from four Danish fields with detailed spray records. Tebuconazole, propiconazole, and
Anders R. Johnsen   +3 more
wiley   +1 more source

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