Results 11 to 20 of about 72,034 (334)
The Lipid Composition of Azole-sensitive and Azole-resistant Strains of Candida albicans [PDF]
Microbiology, 1986 The lipid compositions of two azole-sensitive (A and B2630) and two azole-resistant (AD and KB) strains of the opportunistic fungal pathogen Candida albicans were studied by using several lipid extraction procedures: no differences were observed between the lipid content or total phospholipid/neutral lipid ratios of the four strains.
Christopher A. Hitchcock +2 more
openaire +4 more sources
Azole Resistance in Aspergillus fumigatus: A Consequence of Antifungal Use in Agriculture?
Frontiers in Microbiology, 2017 Agricultural industry uses pesticides to optimize food production for the growing human population. A major issue for crops is fungal phytopathogens, which are treated mainly with azole fungicides.
Sarah Berger +3 more
doaj +2 more sources
High incidence of azole resistance among Candida albicans and C. glabrata isolates in Northeastern Iran [PDF]
Current Medical Mycology, 2021 Background and Purpose: Resistance to antifungal drugs is increasing among Candida isolates from patients with vulvovaginal candidiasis (VVC). Lack of correct diagnosis of Candida causing VVC and the experimental use of antifungal drugs are the main ...
Hossein Zarrinfar +2 more
doaj +1 more source
Combinations of posaconazole and tacrolimus are effective against infections with azole-resistant <i>Aspergillus fumigatus</i>. [PDF]
Front Cell Infect MicrobiolBackgroundSolid organ transplant recipients on immunosuppressants such as tacrolimus are at increased risk of developing pulmonary aspergillosis, a severe to deadly complication with limited treatment options, especially against azole-resistant strains ...
Vanhoffelen E +7 more
europepmc +2 more sources
Microbiology Spectrum, 2022 The emergence of antifungal resistance, especially to the most widely used azole class of ergosterol biosynthesis inhibitors, makes fungal infections difficult to treat in clinics and agriculture. When exposed to azoles, fungi can make adaptive responses
Chengcheng Hu +6 more
doaj +1 more source
Antimicrobial Agents and Chemotherapy, 2022 Trichophyton indotineae causes dermatophytosis that is resistant to terbinafine and azole compounds. The aim of this study was to determine the mechanisms of resistance to itraconazole (ITC) and voriconazole (VRC) in strains of T. indotineae.
Tsuyoshi Yamada +7 more
semanticscholar +1 more source
Antifungal Activity of Minocycline and Azoles Against Fluconazole-Resistant Candida Species
Frontiers in Microbiology, 2021 Candida species are the most common fungal pathogens to infect humans, and can cause life-threatening illnesses in individuals with compromised immune systems.
Jingwen Tan +6 more
doaj +1 more source
New Antifungal Agents with Azole Moieties
Pharmaceuticals, 2022 Fungal conditions affect a multitude of people worldwide, leading to increased hospitalization and mortality rates, and the need for novel antifungals is emerging with the rise of resistance and immunocompromised patients.
M. Teixeira +3 more
semanticscholar +1 more source
PLoS Pathogens, 2021 Aspergillus fumigatus is an opportunistic human pathogen that causes aspergillosis, a spectrum of environmentally acquired respiratory illnesses. It has a cosmopolitan distribution and exists in the environment as a saprotroph on decaying plant matter ...
C. Burks +4 more
semanticscholar +1 more source
Frontiers in Toxicology, 2022 Azoles are antifungal agents used in both agriculture and medicine. They typically target the CYP51 enzyme in fungi and, by so doing, disrupt cell membrane integrity. However, azoles can also target various CYP enzymes in mammals, including humans, which
M. K. Draskau, T. Svingen
semanticscholar +1 more source