Results 31 to 40 of about 56,531 (323)

Differentially Regulated Transcription Factors and ABC Transporters in a Mitochondrial Dynamics Mutant Can Alter Azole Susceptibility of Aspergillus fumigatus

open access: yesFrontiers in Microbiology, 2020
Azole resistance of the fungal pathogen Aspergillus fumigatus is an emerging problem. To identify novel mechanisms that could mediate azole resistance in A.
Laura Sturm   +6 more
doaj   +1 more source

Drug-Resistant Aspergillus spp.: A Literature Review of Its Resistance Mechanisms and Its Prevalence in Europe

open access: yesPathogens, 2023
Infections due to the Aspergillus species constitute an important challenge for human health. Invasive aspergillosis represents a life-threatening disease, mostly in patients with immune defects.
Maria Antonia De Francesco
doaj   +1 more source

An Erg11 lanosterol 14-α-demethylase-Arv1 complex is required for Candida albicans virulence.

open access: yesPLoS ONE, 2020
Azole resistant fungal infections remain a health problem for the immune compromised. Current therapies are limited due to rises in new resistance mechanisms.
Michelle L Villasmil   +4 more
doaj   +1 more source

Azole resistance inCandida

open access: yesEuropean Journal of Clinical Microbiology & Infectious Diseases, 1997
Resistance of Candida to azoles is an increasing problem. Susceptibility testing of Candida against fluconazole and ketoconazole is now feasible and desirable. Good correlation of resistance in vitro with clinical failure of fluconazole therapy has now been shown in mucosal candidiasis.
G. G. Baily   +3 more
openaire   +4 more sources

Recognition of Azole-Resistant Aspergillosis by Physicians Specializing in Infectious Diseases, United States

open access: yesEmerging Infectious Diseases, 2018
Infections caused by pan–azole-resistant Aspergillus fumigatus strains have emerged in Europe and recently in the United States. Physicians specializing in infectious diseases reported observing pan–azole-resistant infections and low rates of ...
Tiffany A. Walker   +8 more
doaj   +1 more source

Biochemical Identification of a Nuclear Coactivator Protein Required for AtrR-Dependent Gene Regulation in Aspergillus fumigatus

open access: yesmSphere, 2022
Azole drugs represent the primary means of treating infections associated with the filamentous fungal pathogen Aspergillus fumigatus. A central player in azole resistance is the Zn2Cys6 zinc cluster-containing transcription factor AtrR.
Sanjoy Paul   +3 more
doaj   +1 more source

Sequencing the Major Mycosphaerella Pathogens of Wheat and Banana [PDF]

open access: yes, 2009
Mycosphaerella is one of the largest genera of plant-pathogenic fungi with more than 1,000 named species, many of which are important pathogens causing leaf spotting diseases in a wide variety of crops including cereals, citrus, banana, eucalypts, soft ...
Kema, G.H.J.
core   +2 more sources

Screening of the central nervous system in children with invasive pulmonary aspergillosis [PDF]

open access: yes, 2014
Peer reviewedPublisher ...
Broenen, Emmi   +5 more
core   +2 more sources

Examining Signatures of Natural Selection in Antifungal Resistance Genes Across Aspergillus Fungi

open access: yesFrontiers in Fungal Biology, 2021
Certain Aspergillus fungi cause aspergillosis, a set of diseases that typically affect immunocompromised individuals. Most cases of aspergillosis are caused by Aspergillus fumigatus, which infects millions of people annually.
Renato Augusto Corrêa dos Santos   +7 more
doaj   +1 more source

Quantification of voriconazole in plasma by liquid chromatography-tandem mass spectrometry [PDF]

open access: yes, 2005
A convenient liquid chromatography-tandem mass spectrometry method for the quantification of the triazole antifungal agent voriconazole in plasma samples is described. Fenbuconazole is used as an internal standard.
Boyd   +16 more
core   +1 more source

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