Results 51 to 60 of about 30,366 (254)

Sterol content analysis suggests altered eburicol 14 alpha-demethylase (CYP51) activity in isolates of Mycosphaerella graminicola adapted to azole fungicides [PDF]

, 2009
The recent decline in the effectiveness of some azole fungicides in controlling the wheat pathogen Mycosphaerella graminicola has been associated with mutations in the CYP51 gene encoding the azole target, the eburicol 14 alpha-demethylase (CYP51), an ...
Bean, T. P., Michael W. Shaw, Shaw, M. W., Bart A. Fraaije, Bean, T. P., Hawkins, N. D., Cools, H. J., Tim P. Bean, Jane L. Ward, Fraaije, B. A., Fraaije, B. A., Shaw, M. W., Hawkins, N. D., John A. Lucas, Ward, J. L., Lucas, J. A., Nathaniel D. Hawkins, Lucas, J. A., Hans J. Cools, Cools, H. J., Ward, J. L.   +20 more
core   +1 more source

Novel Azole-Modified Porphyrins for Mitochondria-Targeted Photodynamic Therapy

Molecules
Photodynamic therapy is a non-invasive treatment strategy for various types of cancer, based on the use of light to activate a photosensitizer which triggers processes leading to cell death.
Sabarinathan Rangasamy, Elisa Bandini, Alessandro Venturini, Giuseppina Bozzuto, Sofia Migani, Annarica Calcabrini, Simona Sennato, Caterina Zuffa, Lucia Maini, Anaïs Brion, Frédéric Bolze, Cecilia Bombelli, Barbara Ventura   +12 more
doaj   +1 more source

Site Selective Nucleophilic Aromatic Substitutions of Azole-Ligated Diaryliodonium Salts [PDF]

, 2022
Diaryliodonium salts are established electrophilic arylation reagents both in transition metal-catalyzed and transition metal-free reaction methods. Herein we present the application of azole-stabilized diaryliodonium salts with additional thiophen-2-yl ...
Nikita S., Antonkin, Thomas J., Kuczmera, Yulia A., Vlasenko, Boris J., Nachtsheim, Pavel S., Postnikov   +4 more
core   +1 more source

Drug-Resistant Aspergillus spp.: A Literature Review of Its Resistance Mechanisms and Its Prevalence in Europe

Pathogens, 2023
Infections due to the Aspergillus species constitute an important challenge for human health. Invasive aspergillosis represents a life-threatening disease, mostly in patients with immune defects.
Maria Antonia De Francesco
doaj   +1 more source

Synthesis and oxidation of some azole-containing thioethers

Beilstein Journal of Organic Chemistry, 2011
Pyrazole and benzotriazole-containing thioethers, namely 1,5-bis(3,5-dimethylpyrazol-1-yl)-3-thiapentane, 1,8-bis(3,5-dimethylpyrazol-1-yl)-3,6-dithiaoctane and 1,3-bis(1,2,3-benzotriazol-1-yl)-2-thiapropane were prepared and fully characterized ...
Andrei S. Potapov, Nina P. Chernova, Vladimir D. Ogorodnikov, Tatiana V. Petrenko, Andrei I. Khlebnikov   +4 more
doaj   +1 more source

Are azole fungicides losing ground against Septoria wheat disease? Resistance mechanisms in Mycosphaerella graminicola [PDF]

, 2008
There has been a recent rapid decline in the efficacy of some, but not all, azole fungicides in controlling the Septoria leaf blotch pathogen of wheat, Mycosphaerella graminicola. Hans J. Cools and Bart A.
Fraaije, B. A., Hans J Cools, Cools, H. J., Bart A Fraaije   +3 more
core   +1 more source

Assessment of azole resistance in healthcare facilities [PDF]

, 2021
Azole resistance among fungal species has been increasing worldwide in recent years, representing a public health concern in the management of fungal infections.
Costa, Natália, Caetano, Liliana Aranha, Cátia Oliveira, Natália Costa, Liliana A. Caetano, Oliveira, Cátia   +5 more
core   +1 more source

High‐Power Rapid Laser‐Induced Synthesis of Multi‐functional Cobalt Metal‐Organic Framework With an Unprecedented Synthesis Efficiency

Advanced Materials Technologies, EarlyView.
Laser‐assisted synthesis enables rapid (within 1 h) and high‐yield (≥90%) production of Co‐MOFs with mesoporous structures, tunable magnetic and optical properties, and efficient adsorption of N2, CH4, and CO2 for low‐energy gas separation. DFT calculations elucidate the electronic structure and adsorption behavior.
Saliha Mutlu, Bülend Ortaç, Ali Karatutlu, Taylan Gorkan, Engin Durgun, Dilek Soyler, Saniye Soylemez, Jelena Lillepäg, Volkan Filiz, Nergis Arsu, Sevil Savaskan Yilmaz   +10 more
wiley   +1 more source

Impact of Recently Emerged Sterol 14 alpha-Demethylase (CYP51) Variants of Mycosphaerella graminicola on Azole Fungicide Sensitivity [PDF]

, 2011
The progressive decline in the effectiveness of some azole fungicides in controllingMycosphaerella graminicola, causal agent of the damaging Septoria leaf blotch disease of wheat, has been correlated with the selection and spread in the ...
Kelly, D. E., Jonathan G. L. Mullins, Bart A. Fraaije, Diane E. Kelly, Jonathan Mullins, Josie Parker, Josie E. Parker, Fraaije, B. A., Steven Kelly, Mullins, J. G. L., Kelly, S. L., Steven L. Kelly, John A. Lucas, Parker, J. E., Diane Kelly, Lucas, J. A., Hans J. Cools, Cools, H. J.   +17 more
core   +1 more source

The one health problem of azole resistance in Aspergillus fumigatus:current insights and future research agenda [PDF]

, 2020
Azole resistance is a concern for the management of diseases caused by Aspergillus fumigatus in humans. Azole fungicide use in the environment has been identified as a possible cause for development of resistance, which increases the complexity and ...
Hoogendijk, Andre, Dyer, P. S., Melchersa, Willem J. G., Bowyer, P., Rietveld, A. G., Melchers, Willem J.G., Kiers, Eric, Kiers, E., Fisher, Matthew C., Denningi, David W., Gisi, Ulrich, Zwaanv, Bas J., Brinkmann, A. J. F., Fraaije, B. A., Bowyer, Paul, Verweij, Paul E., Lucas, J., Rhodes, J., Lagrou, K., Zwaan, B. J., Fisher, M. C., Brinkmann, Arjen J. F., Brinkmann, Arjen J.F., Hermann, D., Rhodes, Johanna; id_orcid, Dyer, Paul S., Geenen, Petra L., Schoustra, Sijmen E., Denning, D. W., Brinkmannh, Arjen J. F., Lagrou, Katrien, Stenzelp, Klaus, Hermanno, Dietrich, Gisin, Ulrich, Denning, David W., Rietveld, Anton G., Melchers, W. J. G., Zwaan, Bas J., Gisi, U., Arendrup, Maiken Cavling, Bowyerg, Paul, Geenen, P. L., Hoogendijkq, Andre, Rhodes, Johanna, Arendrup, M. C., Fraaijec, Bart A., Schoustra, S. E., Geenenm, Petra L., Denning, D W; id_orcid, Lucasc, John A., Arendrupd, Maiken C., Stenzel, K., Verweij, P. E., Dyerk, Paul S., Schoustrav, Sijmen E., Stenzel, Klaus, Fraaije, Bart A., Hoogendijk, A., Fisherl, Matthew C., Rhodesl, Johanna, Lagrous, Katrien, Lucas, John A., Arendrup, Maiken C., Verweija, Paul E., Hermann, Dietrich, Rietveldu, Anton G.   +65 more
core   +1 more source