Results 41 to 50 of about 72,034 (334)
Fungal Resistance to Echinocandins and the MDR Phenomenon in Candida glabrata
Journal of Fungi, 2018 Candida glabrata has thoroughly adapted to successfully colonize human mucosal membranes and survive in vivo pressures. prior to and during antifungal treatment. Out of all the medically relevant Candida species, C.
Kelley R. Healey, David S. Perlin
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Uncovering New Mutations Conferring Azole Resistance in the Aspergillus fumigatus cyp51A Gene
Frontiers in Microbiology, 2020 The opportunistic pathogen Aspergillus fumigatus has developed worldwide resistance to azoles largely through mutations in cytochromeP450 enzyme Cyp51.
Peiying Chen +8 more
doaj +1 more source
Frontiers in Microbiology, 2020 Azole resistance of the fungal pathogen Aspergillus fumigatus is an emerging problem. To identify novel mechanisms that could mediate azole resistance in A.
Laura Sturm +6 more
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Examining Signatures of Natural Selection in Antifungal Resistance Genes Across Aspergillus Fungi
Frontiers in Fungal Biology, 2021 Certain Aspergillus fungi cause aspergillosis, a set of diseases that typically affect immunocompromised individuals. Most cases of aspergillosis are caused by Aspergillus fumigatus, which infects millions of people annually.
Renato Augusto Corrêa dos Santos +7 more
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Azole Antifungal Resistance in Candida albicans and Emerging Non-albicans Candida Species
Frontiers in Microbiology, 2017 Within the limited antifungal armamentarium, the azole antifungals are the most frequent class used to treat Candida infections. Azole antifungals such as fluconazole are often preferred treatment for many Candida infections as they are inexpensive ...
D. Sanglard +7 more
semanticscholar +1 more source
European Journal of Clinical Microbiology & Infectious Diseases, 1997 Resistance of Candida to azoles is an increasing problem. Susceptibility testing of Candida against fluconazole and ketoconazole is now feasible and desirable. Good correlation of resistance in vitro with clinical failure of fluconazole therapy has now been shown in mucosal candidiasis.
G. G. Baily +3 more
openaire +4 more sources
Azole potentiation in Candida species
PLOS Pathogens, 2023 Fungal infections are rising, with over 1.5 billion cases and more than 1 million deaths recorded each year. Among these, Candida infections are frequent in at-risk populations and the rapid development of drug resistance and tolerance contributes to their clinical persistence.
Jan S. Stenkiewicz-Witeska +1 more
openaire +4 more sources
Creation and assessment of a clinical predictive calculator and mortality associated with Candida krusei bloodstream infections [PDF]
, 2018 Background Candida krusei bloodstream infection (CK BSI) is associated with high mortality, but whether this is due to underlying comorbidities in affected patients or the organism itself is unknown.
Hsueh, Kevin +4 more
core +2 more sources
Crystals, 2011 The crystal and molecular structure of the title compound, viz., (2Z)-2-[3-(4-methoxybenzoyl)-4,4-dimethyl-1,2,-oxazolidin-2-ylidene]-1-(4-methoxyphenyl)ethanone (4), is reported.
Robert A. Gossage +4 more
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An Erg11 lanosterol 14-α-demethylase-Arv1 complex is required for Candida albicans virulence.
PLoS ONE, 2020 Azole resistant fungal infections remain a health problem for the immune compromised. Current therapies are limited due to rises in new resistance mechanisms.
Michelle L Villasmil +4 more
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