Results 51 to 60 of about 56,531 (323)

Systematic review of topical treatments for fungal infections of the skin and nails of the feet [PDF]

open access: yes, 1999
OBJECTIVE: To identify and synthesise the evidence for efficacy and cost effectiveness of topical treatments for superficial fungal infections of the skin and nails of the feet. DESIGN: Systematic review. INTERVENTIONS: Topical treatments for superficial
Bell-Syer, Sally E.M.   +5 more
core   +2 more sources

Hospital Environment as a Source of Azole-Resistant Aspergillus fumigatus Strains with TR34/L98H and G448S Cyp51A Mutations

open access: yesJournal of Fungi, 2021
Azole-resistant Aspergillus fumigatus is an emerging worldwide problem with increasing reports of therapy failure cases produced by resistant isolates. A case of azole-resistant A.
Irene Gonzalez-Jimenez   +4 more
doaj   +1 more source

The zinc cluster proteins Upc2 and Ecm22 promote filamentation in Saccharomyces cerevisiae by sterol biosynthesis-dependent and -independent pathways. [PDF]

open access: yes, 2015
The transition between a unicellular yeast form to multicellular filaments is crucial for budding yeast foraging and the pathogenesis of many fungal pathogens such as Candida albicans.
Höfken, T, Woods, K
core   +1 more source

Pharmacokinetic drug interactions of azoles [PDF]

open access: yesCurrent Fungal Infection Reports, 2008
Drug-drug interactions are a major concern with triazoles. Azoles are potent metabolic inhibitors and interactions commonly occur via metabolizing enzymes (ie, cytochrome P450 isoenzyme superfamily) or drug transporters (ie, P-glycoprotein). However, the clinical relevance of these interactions may vary upon the azole involved and upon the “target ...
Bruggemann, R.J.M.   +6 more
openaire   +4 more sources

Covalent Organic Frameworks for Photocatalysis

open access: yesAdvanced Materials, EarlyView.
This review provides an overview of recent advances in covalent organic frameworks (COFs) for photocatalysis, focusing on sustainable energy applications like water splitting, hydrogen peroxide generation, and CO2 and N2 reduction. It discusses design principles, structure‐function relationships, challenges in COF photocatalysis, and strategies to ...
Bikash Mishra   +6 more
wiley   +1 more source

Improvement of experimental testing and network training conditions with genome-wide microarrays for more accurate predictions of drug gene targets [PDF]

open access: yes, 2014
BACKGROUND: Genome-wide microarrays have been useful for predicting chemical-genetic interactions at the gene level. However, interpreting genome-wide microarray results can be overwhelming due to the vast output of gene expression data combined with off-
Christadore, Lisa M.   +3 more
core   +1 more source

Are Point Mutations in HMG-CoA Reductases (Hmg1 and Hmg2) a Step towards Azole Resistance in Aspergillus fumigatus?

open access: yesMolecules, 2021
Invasive aspergillosis, mainly caused by Aspergillus fumigatus, can lead to severe clinical outcomes in immunocompromised individuals. Antifungal treatment, based on the use of azoles, is crucial to increase survival rates.
Irene Gonzalez-Jimenez   +4 more
doaj   +1 more source

N‐Containing Carbon Materials in Metal‐Free and Non‐Noble Metal Liquid Phase Heterogenous Catalysis

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
Over 100 examples of non‐noble metal supported on N‐containing and metal‐free N‐containing carbon catalysts are discussed. Particular emphasis is put on how different N‐functionalities influence catalyst performance and stability. Preparation procedures are also examined, with a strong focus on how the heat treatment temperature influences N ...
Fulvio Varamo, Anna Katharina Beine
wiley   +1 more source

Azole Resistance in Aspergillus fumigatus: A Consequence of Antifungal Use in Agriculture?

open access: yesFrontiers in Microbiology, 2017
Agricultural industry uses pesticides to optimize food production for the growing human population. A major issue for crops is fungal phytopathogens, which are treated mainly with azole fungicides.
Sarah Berger   +3 more
doaj   +1 more source

SIP‐SRS Imaging of Cell Wall Synthesis Identifies a Synergy between Micafungin and Amphotericin B

open access: yesAdvanced Science, EarlyView.
We employed glucose‐d7–based stable isotope probe‐assisted SRS microscopy (SIP‐SRS) C–D imaging to visualize fungal cell wall synthesis and remodeling under antifungal treatment. Amphotericin B (AmB) induced notable daughter cell wall thickening, prompting a combinational therapy with AmB and micafungin.
Meng Zhang   +6 more
wiley   +1 more source

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