Systematic review of topical treatments for fungal infections of the skin and nails of the feet [PDF]
OBJECTIVE: To identify and synthesise the evidence for efficacy and cost effectiveness of topical treatments for superficial fungal infections of the skin and nails of the feet. DESIGN: Systematic review. INTERVENTIONS: Topical treatments for superficial
Bell-Syer, Sally E.M. +5 more
core +2 more sources
Azole-resistant Aspergillus fumigatus is an emerging worldwide problem with increasing reports of therapy failure cases produced by resistant isolates. A case of azole-resistant A.
Irene Gonzalez-Jimenez +4 more
doaj +1 more source
The zinc cluster proteins Upc2 and Ecm22 promote filamentation in Saccharomyces cerevisiae by sterol biosynthesis-dependent and -independent pathways. [PDF]
The transition between a unicellular yeast form to multicellular filaments is crucial for budding yeast foraging and the pathogenesis of many fungal pathogens such as Candida albicans.
Höfken, T, Woods, K
core +1 more source
Pharmacokinetic drug interactions of azoles [PDF]
Drug-drug interactions are a major concern with triazoles. Azoles are potent metabolic inhibitors and interactions commonly occur via metabolizing enzymes (ie, cytochrome P450 isoenzyme superfamily) or drug transporters (ie, P-glycoprotein). However, the clinical relevance of these interactions may vary upon the azole involved and upon the “target ...
Bruggemann, R.J.M. +6 more
openaire +4 more sources
Covalent Organic Frameworks for Photocatalysis
This review provides an overview of recent advances in covalent organic frameworks (COFs) for photocatalysis, focusing on sustainable energy applications like water splitting, hydrogen peroxide generation, and CO2 and N2 reduction. It discusses design principles, structure‐function relationships, challenges in COF photocatalysis, and strategies to ...
Bikash Mishra +6 more
wiley +1 more source
Improvement of experimental testing and network training conditions with genome-wide microarrays for more accurate predictions of drug gene targets [PDF]
BACKGROUND: Genome-wide microarrays have been useful for predicting chemical-genetic interactions at the gene level. However, interpreting genome-wide microarray results can be overwhelming due to the vast output of gene expression data combined with off-
Christadore, Lisa M. +3 more
core +1 more source
Invasive aspergillosis, mainly caused by Aspergillus fumigatus, can lead to severe clinical outcomes in immunocompromised individuals. Antifungal treatment, based on the use of azoles, is crucial to increase survival rates.
Irene Gonzalez-Jimenez +4 more
doaj +1 more source
N‐Containing Carbon Materials in Metal‐Free and Non‐Noble Metal Liquid Phase Heterogenous Catalysis
Over 100 examples of non‐noble metal supported on N‐containing and metal‐free N‐containing carbon catalysts are discussed. Particular emphasis is put on how different N‐functionalities influence catalyst performance and stability. Preparation procedures are also examined, with a strong focus on how the heat treatment temperature influences N ...
Fulvio Varamo, Anna Katharina Beine
wiley +1 more source
Azole Resistance in Aspergillus fumigatus: A Consequence of Antifungal Use in Agriculture?
Agricultural industry uses pesticides to optimize food production for the growing human population. A major issue for crops is fungal phytopathogens, which are treated mainly with azole fungicides.
Sarah Berger +3 more
doaj +1 more source
SIP‐SRS Imaging of Cell Wall Synthesis Identifies a Synergy between Micafungin and Amphotericin B
We employed glucose‐d7–based stable isotope probe‐assisted SRS microscopy (SIP‐SRS) C–D imaging to visualize fungal cell wall synthesis and remodeling under antifungal treatment. Amphotericin B (AmB) induced notable daughter cell wall thickening, prompting a combinational therapy with AmB and micafungin.
Meng Zhang +6 more
wiley +1 more source

