CAQ Corner: Basic concepts of transplant immunology
, 2022 Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley +1 more source
Outcome Analysis of Breakthrough Invasive Aspergillosis on Anti-Mold Azole Prophylaxis and Treatment: 30-Year Experience in Hematologic Malignancy Patients. [PDF]
J Fungi (Basel)Background: Anti-mold azoles have improved the outcomes of invasive aspergillosis (IA) when used therapeutically, but they are extensively used as prophylaxis.
Dagher H +10 more
europepmc +2 more sources
Understanding corrosion inhibition with van der Waals DFT methods: the case of benzotriazole [PDF]
Faraday Discuss. (2015) 180, 439-458, 2015 The corrosion of materials is an undesirable and costly process affecting many areas of technology and everyday life. As such, considerable effort has gone into understanding and preventing it. Organic molecule based coatings can in certain circumstances act as effective corrosion inhibitors.
arxiv +1 more source
Liquid Coordination Polymers with Anhydrous Proton Conductivity
Angewandte Chemie, EarlyView.Functional liquid coordination polymers near ambient conditions are prepared by introducing H3PO4 as a network modifier. This process disrupts extended coordination networks, producing a stable liquid. Liquid properties are controlled by tuning the ratio of network modifiers, resulting in anhydrous proton conductivity up to 27 mS cm−1 at 353 K and ...
Nattapol Ma +3 more
wiley +2 more sources
Absent in vitro interaction between chloroquine and antifungals against Aspergillus fumigatus [PDF]
, 2017 This work was supported by Medical Mycology Section, Department of Medical Microbiology, Radboud University Medical Centre, Nijmegen, the Netherlands.
Seyedmousavi, Seyedmojtaba +3 more
core +1 more source
mSphere, 2022 Azole drugs represent the primary means of treating infections associated with the filamentous fungal pathogen Aspergillus fumigatus. A central player in azole resistance is the Zn2Cys6 zinc cluster-containing transcription factor AtrR.
Sanjoy Paul +3 more
doaj +1 more source
Augmenting Azoles with Drug Synergy to Expand the Antifungal Toolbox
Pharmaceuticals, 2022 Fungal infections impact the lives of at least 12 million people every year, killing over 1.5 million. Wide-spread use of fungicides and prophylactic antifungal therapy have driven resistance in many serious fungal pathogens, and there is an urgent need ...
Aidan Kane, Dee A. Carter
doaj +1 more source
Fungal biofilm resistance [PDF]
, 2012 Fungal biofilm infections have become increasingly recognised as a significant clinical problem. One of the major reasons behind this is the impact that these have upon treatment, as antifungal therapy often fails and surgical intervention is required ...
Rajendran, Ranjith +3 more
core +4 more sources
Antifungal prophylaxis with azole derivatives [PDF]
Clinical Microbiology and Infection, 2004 In recent years, several reports have underlined the increasing role of fungal infections as a cause of morbidity and mortality in hospitalised patients. For this reason, and also in light of the high mortality rate associated with these infections, chemoprophylaxis has been advocated by several authors.
CASTAGNOLA E +3 more
openaire +4 more sources
Population Pharmacokinetic Study of Tacrolimus in Pediatric Patients with Primary Nephrotic Syndrome: A Comparison of Linear and Nonlinear Michaelis Menten Pharmacokinetic Model [PDF]
Eur J Pharm Sci. 2020 Feb 15;143:105199, 2019 Background Little is known about the population pharmacokinetics (PPK) of tacrolimus (TAC) in pediatric primary nephrotic syndrome (PNS). This study aimed to compare the predictive performance between nonlinear and linear PK models and investigate the significant factors of TAC PK characteristics in pediatric PNS.
arxiv +1 more source