ABC transporters and azole susceptibility in laboratory strains of the wheat pathogen Mycosphearella graminicola [PDF]
Laboratory strains of Mycosphaerella graminicola with decreased susceptibilities to the azole antifungal agent cyproconazole showed a multidrug resistance phenotype by exhibiting cross-resistance to an unrelated chemical, cycloheximide or rhodamine 6G ...
Nistelrooy, J.G.M., Van +3 more
core +2 more sources
Creation and assessment of a clinical predictive calculator and mortality associated with Candida krusei bloodstream infections [PDF]
, 2018 Background Candida krusei bloodstream infection (CK BSI) is associated with high mortality, but whether this is due to underlying comorbidities in affected patients or the organism itself is unknown.
Hsueh, Kevin +4 more
core +2 more sources
Visualization of Gaseous Ammonia Using an Ionic Liquid‐Based pH‐Responsive Dye
Analysis &Sensing, EarlyView.An ionic liquid composed of bromocresol purple ([P66614]2[BCP]) is synthesized via an ion‐exchange reaction. The color of [P66,614]2[BCP] changes from yellow to blue after exposure to gaseous NH3. The color change in the [P66614]2[BCP] thin film serves as a visual indicator of pork and salmon decomposition.
Naoya Adachi +3 more
wiley +1 more source
Voluntary Counselling, HIV Testing and Adjunctive Cotrimoxazole Reduces Mortality in Tuberculosis Patients in Thyolo, Malawi. [PDF]
, 2003 OBJECTIVES: To assess the feasibility and effectiveness of voluntary counselling, HIV testing and adjunctive cotrimoxazole in reducing mortality in a cohort of tuberculosis (TB) patients registered under routine programme conditions in a rural district ...
Arendt, V +7 more
core +2 more sources
Untersuchungen über Azole [PDF]
Justus Liebigs Annalen der Chemie, 1889 n ...
openaire +2 more sources
Novel Azole-Modified Porphyrins for Mitochondria-Targeted Photodynamic Therapy
MoleculesPhotodynamic therapy is a non-invasive treatment strategy for various types of cancer, based on the use of light to activate a photosensitizer which triggers processes leading to cell death.
Sabarinathan Rangasamy +12 more
doaj +1 more source
The Hsp90 co-chaperones Sti1, Aha1, and P23 regulate adaptive responses to antifungal azoles
Frontiers in Microbiology, 2016 Heat Shock Protein 90 (Hsp90) is essential for tumor progression in humans and drug resistance in fungi. However, the roles of its many co-chaperones in antifungal resistance are unknown. In this study, by susceptibility test of Neurospora crassa mutants
Xiaokui Gu +5 more
doaj +1 more source
Mitochondrial Complex I Is a Global Regulator of Secondary Metabolism, Virulence and Azole Sensitivity in Fungi. [PDF]
PLoS ONE, 2016 Recent estimates of the global burden of fungal disease suggest that that their incidence has been drastically underestimated and that mortality may rival that of malaria or tuberculosis.
Mike Bromley +11 more
doaj +1 more source
Challenges in optimizing tacrolimus therapy in patients treated with rifampin: A case series
British Journal of Clinical Pharmacology, EarlyView.Tacrolimus is a cornerstone immunosuppressant in transplantation medicine with a narrow therapeutic window. Drug–drug interactions with strong CYP3A4 and P‐glycoprotein modulators, such as rifampin and azole antifungals, significantly alter tacrolimus exposure and complicate therapy. Two transplant cases illustrates the impact of rifampin on tacrolimus
Jeroen P. A. Houwen +6 more
wiley +1 more source
Molecular Detection of Azole-Resistant Aspergillus fumigatus in Clinical Samples
Frontiers in Microbiology, 2018 Aspergillus diseases are often caused by Aspergillus fumigatus. Azoles are the mainstay of therapy, but the management of aspergillosis is hampered by the emergence of azole resistance.
Jochem B. Buil +7 more
doaj +1 more source