Results 1 to 10 of about 21,150 (298)

ST-Producing E. coli Oppose Carcinogen-Induced Colorectal Tumorigenesis in Mice [PDF]

Toxins, 2017
There is a geographic inequality in the incidence of colorectal cancer, lowest in developing countries, and greatest in developed countries.
Peng Li, Jieru E. Lin, Adam E. Snook, Scott A. Waldman   +3 more
doaj   +3 more sources

Genetic and microbial determinants of azoxymethane-induced colorectal tumor susceptibility in Collaborative Cross mice and their implication in human cancer [PDF]

Gut Microbes
The insights into interactions between host genetics and gut microbiome (GM) in colorectal tumor susceptibility (CTS) remains lacking. We used Collaborative Cross mouse population model to identify genetic and microbial determinants of Azoxymethane ...
Dan Li, Chenhan Zhong, Mengyuan Yang, Li He, Hang Chang, Ning Zhu, Susan E Celniker, David W Threadgill, Antoine M Snijders, Jian-Hua Mao, Ying Yuan   +10 more
doaj   +2 more sources

Characterization of hepatic pathology during azoxymethane-induced acute liver failure. [PDF]

World J Gastroenterol
BACKGROUND Acute liver failure (ALF) is a loss of liver function due to a severe hepatic insult. Studies utilizing the azoxymethane (AOM) mouse model of ALF, which also generates hepatic encephalopathy, have primarily focused on development of neurological deficits.
Bhattarai SM, Jhawer A, Frampton G, Troyanovskaya E, DeMorrow S, McMillin M.   +5 more
europepmc   +3 more sources

Freeze-Dried Ham Promotes Azoxymethane-Induced Mucin-Depleted Foci and Aberrant Crypt Foci in Rat Colon [PDF]

, 2010
Processed and red meat consumption is associated with the risk of colorectal cancer. Meta-analyses have suggested that the risk associated with processed meat is higher. Most processed meats are cured and cooked, which leads to formation of free nitrosyl
Bonneson C, Caderni G, Cross A J, Cummings J H, Denis E. Corpet, Fabrice H. F. Pierre, Françoise Guéraud, Karkare M R, Nathalie Naud, Ossama Allam, Pierre F, Raphaëlle L. Santarelli, Sandhu M S, Sesink A LA, Sinha R, Sylviane Taché, Van Den Berg J W   +16 more
core   +6 more sources

Targeted deletion of the metastasis-associated phosphatase Ptp4a3 (PRL-3) suppresses murine colon cancer. [PDF]

PLoS ONE, 2013
Ptp4a3 (commonly known as PRL-3) is an enigmatic member of the Ptp4a family of prenylated protein tyrosine phosphatases that are highly expressed in many human cancers.
Mark W Zimmerman, Gregg E Homanics, John S Lazo   +2 more
doaj   +7 more sources

Repercussão hepática da carcinogênese colorretal induzida pelo azoximetano Hepatic repercussions of azoxymethane-induced colorectal carcinogenesis

Revista do Colégio Brasileiro de Cirurgiões, 2013
OBJETIVO: Avaliar as repercussões hepáticas da carcinogênese colônica induzida por diferentes doses e tempos de exposição ao azoximetano em ratos Wistar. MÉTODOS: Quarenta e quatro ratos foram distribuídos em quatro grupos. Os animais tinham oito semanas
Idália Maria Brasil Burlamaqui, Conceição Aparecida Dornelas, Paulo Roberto Carvalho Almeida, Francisco Vagnaldo Fechine Jamacaru, Daniel Magalhães Coutinho Mota, Francisco José Cabral Mesquita, Lara Albuquerque de Brito, Lara Burlamaqui Veras, Lusmar Veras Rodrigues   +8 more
doaj   +1 more source

Mitochondrial DNA Damage and Histological Features in Liver Tissue of Azoxymethane-Treated <i>Apex1</i> Haploinsufficient Mice. [PDF]

Biomolecules
Pérez-Pérez CM, Rodríguez-Muñoz A, Mackenzie GG, Matsukuma KE, Castro-Achi MR, Ayala-Peña S, Torres-Ramos CA.   +6 more
europepmc   +3 more sources

Cardamonin Attenuates Experimental Colitis and Associated Colorectal Cancer

Biomolecules, 2021
Cardamonin is a naturally occurring chalcone, majorly from the Zingiberaceae family, which includes a wide range of spices from India. Herein, we investigated the anti-inflammatory property of cardamonin using different in vitro and in vivo systems.
Shirley James, Jayasekharan S. Aparna, Anu Babu, Aswathy Mary Paul, Manendra Babu Lankadasari, Subha R. Athira, Sreesha S. Kumar, Yadu Vijayan, Narayanan N. Namitha, Sabira Mohammed, Girijadevi Reshmi, Kuzhuvelil B. Harikumar   +11 more
doaj   +1 more source

Therapeutic Potential of 6-Gingerol in Prevention of Colon Cancer Induced by Azoxymethane through the Modulation of Antioxidant Potential and Inflammation

Current Issues in Molecular Biology, 2022
A polyphenolic component of ginger, 6-gingerol, is widely reported to possess antioxidant, anti-inflammatory and anticancer activities. In the current study, it was aimed to investigate the anticancer effects of 6-gingerol (6-Gin) on azoxymethane (AOM ...
Abdulaziz A. Aloliqi
doaj   +1 more source

Dietary phytate lowers K-ras mutational frequency, decreases DNA-adduct and hydroxyl radical formation in azoxymethane-induced colon cancer [PDF]

Iranian Journal of Basic Medical Sciences, 2020
Objective(s): Dietary phytate is known to protect against azoxymethane (AOM)-induced preneoplastic lesions.  The present study was designed to determine whether dietary phytate affects mutation frequency in colon epithelial cells challenged with ...
Poorna Venkata Satya Prasad Pallem, Sreedhar Bodiga, Vijaya Lakshmi Bodiga   +2 more
doaj   +1 more source