Results 11 to 20 of about 15,703 (232)

Mesenchymal Stem Cells Cancel Azoxymethane-Induced Tumor Initiation [PDF]

Stem Cells, 2014
Abstract The role of mesenchymal stem cells (MSCs) in tumorigenesis remains controversial. Therefore, our goal was to determine whether exogenous MSCs possess intrinsic antineoplastic or proneoplastic properties in azoxymethane (AOM)-induced carcinogenesis.
Masanao, Nasuno, Yoshiaki, Arimura, Kanna, Nagaishi, Hiroyuki, Isshiki, Kei, Onodera, Suguru, Nakagaki, Shuhei, Watanabe, Masashi, Idogawa, Kentaro, Yamashita, Yasuyoshi, Naishiro, Yasushi, Adachi, Hiromu, Suzuki, Mineko, Fujimiya, Kohzoh, Imai, Yasuhisa, Shinomura   +14 more
openaire   +2 more sources

Characterization of hepatic pathology during azoxymethane-induced acute liver failure. [PDF]

World J Gastroenterol
BACKGROUND Acute liver failure (ALF) is a loss of liver function due to a severe hepatic insult. Studies utilizing the azoxymethane (AOM) mouse model of ALF, which also generates hepatic encephalopathy, have primarily focused on development of neurological deficits.
Bhattarai SM, Jhawer A, Frampton G, Troyanovskaya E, DeMorrow S, McMillin M.   +5 more
europepmc   +3 more sources

Colon carcinogenesis in wild type and immune compromised mice after treatment with azoxymethane, and azoxymethane with dextran sodium sulfate [PDF]

Molecular Carcinogenesis, 2015
The association between inflammation and the risk of colorectal cancer (CRC) is well documented in animal models and in humans, but the mechanistic role of inflammation in CRC is less well understood. To address this question, the induction of colon tumors was evaluated in (i) wild type (WT) and athymic BALB/c mice treated with the colon carcinogen ...
Whetstone, Ryan D., Wittel, Uwe A., Michels, Nicole M., Gulizia, James M., Gold, Barry   +4 more
openaire   +3 more sources

Insufficient Expression of the Autophagic Protein ATG16L1 Results in Accelerated Carcinogenesis Related to an Aberrant B Cell Response. [PDF]

Cancer Rep (Hoboken)
ABSTRACT Background Autophagy‐related proteins (ATGs) regulate a great variety of cellular responses beyond autophagy. In cancer, the role of ATG proteins is central, as evidenced in spontaneous cancer emerging in animals lacking ATG proteins. Aim To determine whether ATG16L1 may be participating in tumorigenesis in colonic and oral mucosa and its ...
Mendiola D, Ortiz B, Nieto O, González MI, Vannan D, Eksteen B, Martínez A, Mateos D, Mendoza-Rodríguez MG, Rodríguez-Sosa M, Terrazas LI, Reyes JL.   +11 more
europepmc   +2 more sources

American ginseng attenuates azoxymethane/dextran sodium sulfate-induced colon carcinogenesis in mice

Journal of Ginseng Research, 2015
Background: Colorectal cancer is a leading cause of cancer-related death, and inflammatory bowel disease is a risk factor for this malignancy. We previously reported colon cancer chemoprevention potential using American ginseng (AG) in a xenograft mice ...
Chunhao Yu, Xiao-Dong Wen, Zhiyu Zhang, Chun-Feng Zhang, Xiao-Hui Wu, Adiba Martin, Wei Du, Tong-Chuan He, Chong-Zhi Wang, Chun-Su Yuan   +9 more
doaj   +1 more source

Dehydroalanine and Lysinoalanine in Thermolyzed Casein do not Promote Colon Cancer in the Rat [PDF]

, 2008
Thermolysis of proteins produces xenobiotic amino-acids such as the potentially toxic lysinoalanine, and the alkylating agent, dehydro¬alanine, which have been considered possible health hazards.
AIN, Bachmeier, Bartone, Bird, Cattaneo, Cheftel, Corpet, Corpet, Corpet, Corpet, Corpet, Corpet, Corpet, De Groot, Deng, Denis E. Corpet, D’Agostina, Finley, Friedman, Gerb er, Kleyn, Kumar, Lutz, Maga, Masri, Michael C. Archer, Parnaud, Pintauro, Sternberg, Struthers, Sugimura, Sylviane Taché, Vlassara, Vo, W. Robert Bruce, Wenzel, Zhang   +36 more
core   +3 more sources

Effect of Tarantula cubensis alcohol extract and Capecitabin combine in Colorectal Cancer rats

Revista Científica, 2023
Colon cancer (CRC) is one of the most common types of cancer in the world. In this study, the effects of Tarantula cubensis alcoholic extract (TCAE) and the Capecitabine in CRC were investigated. Wistar albino rats were divided into eight groups with 12
Rahmi Canbar, Ozgur Ozdemir, Ahmet Levent Bas   +2 more
doaj   +1 more source

Beef meat promotion of dimethylhydrazine-induced colorectal carcinogenesis biomarkers is suppressed by dietary calcium [PDF]

, 2007
Red meat consumption is associated with increased risk of colorectal cancer. We have previously shown that haemin, Hb and red meat promote carcinogen-induced preneoplastic lesions: aberrant crypt foci (ACF) and mucin-depleted foci (MDF) in rats.
Corpet, Denis E., Guéraud, Françoise, Pierre, Fabrice, Santarelli, Raphaëlle L., Taché, Sylviane   +4 more
core   +4 more sources

Freeze-Dried Ham Promotes Azoxymethane-Induced Mucin-Depleted Foci and Aberrant Crypt Foci in Rat Colon [PDF]

, 2010
Processed and red meat consumption is associated with the risk of colorectal cancer. Meta-analyses have suggested that the risk associated with processed meat is higher. Most processed meats are cured and cooked, which leads to formation of free nitrosyl
Bonneson C, Caderni G, Cross A J, Cummings J H, Denis E. Corpet, Fabrice H. F. Pierre, Françoise Guéraud, Karkare M R, Nathalie Naud, Ossama Allam, Pierre F, Raphaëlle L. Santarelli, Sandhu M S, Sesink A LA, Sinha R, Sylviane Taché, Van Den Berg J W   +16 more
core   +4 more sources

Increased colon tumor susceptibility in azoxymethane treated CEABAC transgenic mice [PDF]

Carcinogenesis, 2006
Human carcinoembryonic antigen (CEA), a widely used clinical tumor marker, and its close relative, CEACAM6, are often overexpressed in many cancers. This correlation suggests a possible instrumental role in tumorigenesis, which is supported by extensive results obtained with several in vitro systems.
Carlos H F, Chan, Denise, Cook, Clifford P, Stanners   +2 more
openaire   +2 more sources