Results 21 to 30 of about 10,720 (219)

Induction of Colonic Aberrant Crypts in Mice by Feeding Apparent N-Nitroso Compounds Derived From Hot Dogs [PDF]

open access: yes, 2012
Nitrite-preserved meats (e.g., hot dogs) may help cause colon cancer because they contain N-nitroso compounds. We tested whether purified hot-dog-derived total apparent N-nitroso compounds (ANC) could induce colonic aberrant crypts, which are putative ...
Mirvish, Sidney S.   +12 more
core   +1 more source

How good are rodent models of carcinogenesis in predicting efficacy in humans? A systematic review and meta-analysis of colon chemoprevention in rats, mice and men [PDF]

open access: yes, 2005
Tumours in rodent and human colon share many histological and genetic features. To know if rodent models of colon carcinogenesis are good predictors of chemopreventive efficacy in humans, we made a meta-analysis of aspirin, beta-carotene, calcium, and ...
Denis E. Corpet   +4 more
core   +1 more source

(I) Early Alterations of Apoptosis and Cell Proliferation in Azoxymethane-initiated Rat Colonic Epithelium (II) Expression of Bcl-2, Bax and Bcl-XL proteins in the azoxymethane-induced rat colonic adenocarcinomas [PDF]

open access: yes, 1997
博士論文 (Doctoral dissertation)(I) Early Alterations of Apoptosis and Cell Proliferation in Azoxymethane-initiated Rat Colonic Epithelium(II) Expression of Bcl-2, Bax and Bcl-XL proteins in the azoxymethane-induced rat colonic ...
廣瀬, 善信, 397036
core   +2 more sources

6-Bromoisatin Found in Muricid Mollusc Extracts Inhibits Colon Cancer Cell Proliferation and Induces Apoptosis, Preventing Early Stage Tumor Formation in a Colorectal Cancer Rodent Model

open access: yesMarine Drugs, 2013
Muricid molluscs are a natural source of brominated isatin with anticancer activity. The aim of this study was to examine the safety and efficacy of synthetic 6-bromoisatin for reducing the risk of early stage colorectal tumor formation. The purity of 6-
Babak Esmaeelian   +3 more
doaj   +1 more source

Effect of Tarantula cubensis alcoholic extract and Nerium oleander distillate on cell proliferation markers in colon carcinogenesis

open access: yesRevista Científica, 2022
Colorectal Cancer (CRC) is defined as colon and rectum cancer and is among the major causes of mortality in developed Countries. Tarantula cubensis alcoholic extract (TCAE) and Nerium oleander distillate (NOD) are reported to have anticancer and ...
Ozgur Ozdemir   +2 more
doaj   +1 more source

Mouse Models for Application in Colorectal Cancer: Understanding the Pathogenesis and Relevance to the Human Condition

open access: yesBiomedicines, 2022
Colorectal cancer (CRC) is a malignant disease that is the second most common cancer worldwide. CRC arises from the complex interactions among a variety of genetic and environmental factors. To understand the mechanism of colon tumorigenesis, preclinical
Chuangen Li   +3 more
doaj   +1 more source

Targeted deletion of the metastasis-associated phosphatase Ptp4a3 (PRL-3) suppresses murine colon cancer. [PDF]

open access: yesPLoS ONE, 2013
Ptp4a3 (commonly known as PRL-3) is an enigmatic member of the Ptp4a family of prenylated protein tyrosine phosphatases that are highly expressed in many human cancers.
Mark W Zimmerman   +2 more
doaj   +1 more source

Dehydroalanine and Lysinoalanine in Thermolyzed Casein do not Promote Colon Cancer in the Rat [PDF]

open access: yes, 2008
Thermolysis of proteins produces xenobiotic amino-acids such as the potentially toxic lysinoalanine, and the alkylating agent, dehydro¬alanine, which have been considered possible health hazards.
Bruce, W Robert   +5 more
core   +1 more source

Heme iron from meat and risk of colorectal cancer: a meta-analysis and a review of the mechanisms involved [PDF]

open access: yes, 2011
Red meat and processed meat intake is associated with a risk of colorectal cancer, a major cause of death in affluent countries. Epidemiological and experimental evidence supports the hypothesis that heme iron present in meat promotes colorectal cancer ...
Bastide, Nadia   +6 more
core   +1 more source

The mouse CRC model was induced using the azoxymethane/dextran sulfate sodium salt method.

open access: yes, 2023
The mouse CRC model was induced using the azoxymethane/dextran sulfate sodium salt method.
Jinhua Tian (5655472)   +8 more
core   +1 more source

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