Results 21 to 30 of about 8,111 (184)

ST-Producing E. coli Oppose Carcinogen-Induced Colorectal Tumorigenesis in Mice

Toxins, 2017
There is a geographic inequality in the incidence of colorectal cancer, lowest in developing countries, and greatest in developed countries.
Peng Li, Jieru E. Lin, Adam E. Snook, Scott A. Waldman   +3 more
doaj   +1 more source

Mesenchymal Stem Cells Cancel Azoxymethane-Induced Tumor Initiation [PDF]

Stem Cells, 2014
Abstract The role of mesenchymal stem cells (MSCs) in tumorigenesis remains controversial. Therefore, our goal was to determine whether exogenous MSCs possess intrinsic antineoplastic or proneoplastic properties in azoxymethane (AOM)-induced carcinogenesis.
Masanao, Nasuno, Yoshiaki, Arimura, Kanna, Nagaishi, Hiroyuki, Isshiki, Kei, Onodera, Suguru, Nakagaki, Shuhei, Watanabe, Masashi, Idogawa, Kentaro, Yamashita, Yasuyoshi, Naishiro, Yasushi, Adachi, Hiromu, Suzuki, Mineko, Fujimiya, Kohzoh, Imai, Yasuhisa, Shinomura   +14 more
openaire   +2 more sources

Increased Incidence of Colon Tumors in AOM-Treated Apc1638N/+ Mice Reveals Higher Frequency of Tumor Associated Neutrophils in Colon Than Small Intestine

Frontiers in Oncology, 2019
Colorectal cancer (CRC) is one of the most common cancers and a major cause of mortality. Mice with truncating Apc germline mutations have been used as a standard model of CRC, but most of the Apc-mutated lines develop multiple tumors in the proximal ...
Rebecca Metzger, Mahulena Maruskova, Sabrina Krebs, Klaus-Peter Janssen, Anne B. Krug   +4 more
doaj   +1 more source

Apis meliffera intermissa venom attenuated colitis-associated cancer progression in azoxymethane treated mice [PDF]

Archives of Razi Institute
Colitis-associated colorectal cancer (CAC) is a serious condition driven by chronic inflammation in the colon, representing a significant challenge in both preventative and therapeutic contexts.
Faouzi Dahdouh, Hanane Chainez Djeffal, Amira Bourouba, Rania Bousba, Amina Bourouba, Houria Djebar - Berrebbah   +5 more
doaj   +1 more source

Gum arabic and red propolis protecteting colorectal preneoplastic lesions in a rat model of azoxymethane [PDF]

Acta Cirúrgica Brasileira, 2019
Purpose: To evaluate red propolis, gum arabic and L-lysine activity on colorectal preneoplastic lesions induced by azoxymethane (AOM). Methods: The study featured 4 control groups (I-IV) and 4 experimental groups (V-VIII), totaling 48 rats. Once a week
Vanessa Nogueira Lages Braga, Camila de Carvalho Juanes, Hélio de Souza Peres Júnior, José Robson de Sousa, Bruno Coêlho Cavalcanti, Francisco Vagnaldo Fechine Jamacaru, Telma Leda Gomes de Lemos, Conceição Aparecida Dornelas   +7 more
doaj   +1 more source

Insufficient Expression of the Autophagic Protein ATG16L1 Results in Accelerated Carcinogenesis Related to an Aberrant B Cell Response. [PDF]

Cancer Rep (Hoboken)
ABSTRACT Background Autophagy‐related proteins (ATGs) regulate a great variety of cellular responses beyond autophagy. In cancer, the role of ATG proteins is central, as evidenced in spontaneous cancer emerging in animals lacking ATG proteins. Aim To determine whether ATG16L1 may be participating in tumorigenesis in colonic and oral mucosa and its ...
Mendiola D, Ortiz B, Nieto O, González MI, Vannan D, Eksteen B, Martínez A, Mateos D, Mendoza-Rodríguez MG, Rodríguez-Sosa M, Terrazas LI, Reyes JL.   +11 more
europepmc   +2 more sources

EFEK PEMBERIAN EKSTRAK DAUN Carica pubescens TERHADAP JUMLAH LIMFOSIT TIKUS Sprague dawley YANG DIINDUKSI AZOXYMETHANE : STUDI DI LABORATORIUM PENELITIAN DAN PENGUJIAN TERPADU 4 UNIVERSITAS GADJAH MADA

Jurnal Kedokteran Diponegoro, 2019
Latarbelakang: Inflamasi merupakan salah satu faktor yang berperan penting dalam patofisiologi kanker kolorektal. Daun Carica pubescens yang mengandung flavonoid berpotensi sebagai agen preventif kanker kolorektal.
Maharani Shofa Yudina, Ainun Rahmasari Gumay, Muflihatul Muniroh   +2 more
doaj   +1 more source

A20 Restricts NOS2 Expression and Intestinal Tumorigenesis in a Mouse Model of Colitis-Associated Cancer

Gastro Hep Advances, 2023
Background and Aims: Colon cancer can occur sporadically or in the setting of chronic inflammation, such as in patients with inflammatory bowel disease.
David W. Basta, Mandy Vong, Adolat Beshimova, Brooke N. Nakamura, Iulia Rusu, Michael G. Kattah, Ling Shao   +6 more
doaj   +1 more source

Bekatul Beras Hitam Terfermentasi Memperbaiki Kondisi Kolon Mencit yang Diinduksi Senyawa Karsinogen Azoxymethane

Jurnal Teknologi dan Industri Pangan, 2023
Worldwide, colon cancer has become the fourth cause of death in terms of cancer. A high fiber and antioxidants diet help promote a healthy diet and prevent colon cancer. Black rice bran has high content both in fiber and phenolic.
Nouverra Nadya Putri, Slamet Budijanto, Endang Prangdimurti, Bambang Pontjo   +3 more
doaj   +1 more source

EFEK PEMBERIAN EKSTRAK DAUN CARICA PUBESCENS TERHADAP JUMLAH NEUTROFIL PADA TIKUS SPRAGUE DAWLEY YANG DIINDUKSI AZOXYMETHANE

Jurnal Kedokteran Diponegoro, 2019
Latar Belakang : Inflamasi yang terjadi terus menerus adalah salah satu penyebab terjadinya kanker kolorektal. Ekstrak daun Carica pubescens mengandung flavonoid yang memiliki efek antiinflamasi diyakini mampu menurunkan jumlah sel neutrofil.
Faradilla Nadya Blezeinsky, Ainun Rahmasari Gumay, Hardian Hardian   +2 more
doaj   +1 more source