Results 171 to 180 of about 10,720 (219)
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Chemoprevention of Azoxymethane-induced Colon Carcinogenesis by Delta-Tocotrienol
Cancer Prevention Research, 2019Abstract This study evaluated the preclinical activity of δ-tocotrienol (DT3), a bioactive form of vitamin E, in the inhibition of colorectal cancer growth and development in vitro and in vivo. DT3 is the most bioactive isomer of vitamin E in inhibiting growth of colorectal cancer cells.
Kazim Husain +6 more
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Effect of black tea on azoxymethane-induced colon cancer
Carcinogenesis, 1998Two sets of experiments on the role of tea in azoxymethane (AOM) induced colon cancer were performed. The first test involved male F344 rats given 1.25% solutions of black tea beginning at 5 weeks of age and ending at 51 days of age. At 6 and 7 weeks of age, they received 15 mg/kg AOM and were held for 50 weeks. Another group received the AOM dosage at
J H, Weisburger +6 more
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Cellulose Dietary Bulk and Azoxymethane-Induced Intestinal Cancer
Journal of the National Cancer Institute, 1973Summary A model experiment explored the significance of bulk in colon cancer production. Male Fischer strain rats were fed either a low-residue semisynthetic diet or the same diet containing 20% and 40% of its bulk as cellulose. All animals were given injections of 14.8 mg azoxymethane/kg body weight once a week for 10 weeks and held ...
J M, Ward +2 more
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AZOXYCOMPOUNDS: I. THE PHOTOLYSIS OF AZOXYMETHANE
Canadian Journal of Chemistry, 1964A study of the photolysis of azoxymethane has been made. The reaction products include nitrogen, nitrous oxide, methane, and ethane. The ratio N2:N2O is independent of temperature and two primary photolytic processes are postulated to account for this fact.
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Inhibition of Azoxymethane-Induced Colon Cancer by Orange Juice
Nutrition and Cancer, 2000Previous research has shown that hesperidin, a flavanone glycoside in orange juice, inhibits colon carcinogenesis and that feeding double-strength orange juice delays the onset of chemically induced mammary cancer in rats. This study determined whether feeding single-strength, pasteurized orange juice would inhibit azoxymethane (AOM)-induced colon ...
Y, Miyagi +3 more
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Effect of propylthiouracil on intestinal tumor formation by azoxymethane in rats
Experientia, 1977Treatment with propylthiouracil (PTU) resulted in a significant decrease in azoxymethane-induced intestinal tumors, total concentration of fecal bile acids as well as the fecal neutral steroids, cholesterol and coprostanol. Thus, a hypothyroid state induced by PTU treatment may affect intestinal carcinogenesis in this animal model by lowering the ...
D V, Singh +3 more
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The Azoxymethane/Il10 −/− Model of Colitis-Associated Cancer (CAC)
2019Mouse models have proved essential for generating a mechanistic understanding of human disease processes. The azoxymethane/interleukin-10 knockout (AOM/Il10-/-) model is a powerful tool for assessing the effects of intestinal microbiota and inflammation on colon tumorigenesis.
Aaron, Rothemich, Janelle C, Arthur
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ChemInform Abstract: Synthesis of Vinyloxy‐NNO‐azoxymethane.
ChemInform, 1999AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
I. N. Zyuzin, G. N. Nechiporenko
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Neurobiological characterization of an azoxymethane mouse model of acute liver failure
Neurochemistry International, 2006Molecular biological approaches continue to lead to the identification of alterations in expression of genes coding for key central nervous system proteins involved in water homeostasis, energy metabolism and neurotransmitter regulation in acute liver failure (ALF).
Mireille, Bélanger +2 more
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Aging alters acute apoptotic response to azoxymethane in the colon of rats
Experimental Gerontology, 2007Deregulation of apoptosis seems to contribute to the aging process in post-mitotic tissues. However, the effect of aging on regulation of apoptosis in the colon is largely unknown. We induced colonic apoptosis using azoxymethane (AOM) in three different aged (6 week, 12 month, and 22 month) F344 rats and assessed age-related differences in induction ...
Youngjoo, Kwon, Bernadene A, Magnuson
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