Results 41 to 50 of about 15,583 (213)

A20 Restricts NOS2 Expression and Intestinal Tumorigenesis in a Mouse Model of Colitis-Associated Cancer

Gastro Hep Advances, 2023
Background and Aims: Colon cancer can occur sporadically or in the setting of chronic inflammation, such as in patients with inflammatory bowel disease.
David W. Basta, Mandy Vong, Adolat Beshimova, Brooke N. Nakamura, Iulia Rusu, Michael G. Kattah, Ling Shao   +6 more
doaj   +1 more source

Freeze-Dried Ham Promotes Azoxymethane-Induced Mucin-Depleted Foci and Aberrant Crypt Foci in Rat Colon [PDF]

, 2010
Processed and red meat consumption is associated with the risk of colorectal cancer. Meta-analyses have suggested that the risk associated with processed meat is higher. Most processed meats are cured and cooked, which leads to formation of free nitrosyl
Bonneson C, Caderni G, Cross A J, Cummings J H, Denis E. Corpet, Fabrice H. F. Pierre, Françoise Guéraud, Karkare M R, Nathalie Naud, Ossama Allam, Pierre F, Raphaëlle L. Santarelli, Sandhu M S, Sesink A LA, Sinha R, Sylviane Taché, Van Den Berg J W   +16 more
core   +4 more sources

Comparative study of 1,2-dimethylhydrazine and azoxymethane on the induction of colorectal cancer in rats

Journal of Coloproctology, 2014
The induced colorectal carcinogenesis in rodents has a long history and currently uses the substances 1,2-dimethylhydrazine and azoxymethane. Objective: The aim of this study was to compare the inductive effect of the substances azoxymethane and 1,2 ...
Mario Jorge Jucá, Bruno Carneiro Bandeira, Davi Silva Carvalho, Antenor Teixeira Leal   +3 more
doaj   +1 more source

Bekatul Beras Hitam Terfermentasi Memperbaiki Kondisi Kolon Mencit yang Diinduksi Senyawa Karsinogen Azoxymethane

Jurnal Teknologi dan Industri Pangan, 2023
Worldwide, colon cancer has become the fourth cause of death in terms of cancer. A high fiber and antioxidants diet help promote a healthy diet and prevent colon cancer. Black rice bran has high content both in fiber and phenolic.
Nouverra Nadya Putri, Slamet Budijanto, Endang Prangdimurti, Bambang Pontjo   +3 more
doaj   +1 more source

EFEK PEMBERIAN EKSTRAK DAUN CARICA PUBESCENS TERHADAP JUMLAH NEUTROFIL PADA TIKUS SPRAGUE DAWLEY YANG DIINDUKSI AZOXYMETHANE

Jurnal Kedokteran Diponegoro, 2019
Latar Belakang : Inflamasi yang terjadi terus menerus adalah salah satu penyebab terjadinya kanker kolorektal. Ekstrak daun Carica pubescens mengandung flavonoid yang memiliki efek antiinflamasi diyakini mampu menurunkan jumlah sel neutrofil.
Faradilla Nadya Blezeinsky, Ainun Rahmasari Gumay, Hardian Hardian   +2 more
doaj   +1 more source

Uncoupled nitric oxide synthase activity promotes colorectal cancer progression

Frontiers in Oncology, 2023
Increased levels of reactive oxygen/nitrogen species are one hallmark of chronic inflammation contributing to the activation of pro-inflammatory/proliferative pathways. In the cancers analyzed, the tetrahydrobiopterin:dihydrobiopterin ratio is lower than
Asim Alam, Steven C. Smith, Sundaresan Gobalakrishnan, Mina McGinn, Vasily A. Yakovlev, Christopher S. Rabender   +5 more
doaj   +1 more source

Lymphoma caused by intestinal microbiota. [PDF]

, 2014
The intestinal microbiota and gut immune system must constantly communicate to maintain a balance between tolerance and activation: on the one hand, our immune system should protect us from pathogenic microbes and on the other hand, most of the millions ...
Schiestl, Robert H, Yamamoto, Mitsuko L
core   +2 more sources

Targeting Peptostreptococcus anaerobius with an Iron‐Based Nanozyme Reverses Ferroptosis Resistance and Enhances Antitumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao, Jun Wang, Hanwenchen Wang, Xiang Sun, Fang Fang, Shiying Li, Jianping Liu, Changrong Shi, Pengyuan Qi, Jianhua Zou, Xiaoyuan Chen, Kailin Cai   +11 more
wiley   +1 more source

Study on the effect and mechanism of Lacticaseibacillus rhamnosus AFY06 on inflammation-associated colorectal cancer induced by AOM/DSS in mice

Frontiers in Microbiology
IntroductionLacticaseibacillus rhamnosus AFY06 (LR-AFY06) is a microorganism isolated from naturally fermented yogurt in Xinjiang, China.MethodsIn this study, we investigated the effects and mechanisms of LR-AFY06 in a mouse model of inflammation ...
Jing Zhang, Piyun Zhang, Sijia Li, Ting Yu, Xiangyu Lai, Yongpeng He   +5 more
doaj   +1 more source

Chemopreventive evaluation of a Schiff base derived copper (II) complex against azoxymethane-induced colorectal cancer in rats.

PLoS ONE, 2014
BackgroundBased on the potential of Schiff base compounds to act as sources for the development of cancer chemotherapeutic agents, this in vivo study was performed to investigate the inhibitory properties of the synthetic Schiff base compound Cu(BrHAP)2 ...
Maryam Hajrezaie, Pouya Hassandarvish, Soheil Zorofchian Moghadamtousi, Nura Suleiman Gwaram, Shahram Golbabapour, Abdrabuh Najihussien, Amel Abdullah Almagrami, Maryam Zahedifard, Elham Rouhollahi, Hamed Karimian, Somaye Fani, Behnam Kamalidehghan, Nazia Abdul Majid, Hapipah Mohd Ali, Mahmood Ameen Abdulla   +14 more
doaj   +1 more source