Results 51 to 60 of about 21,150 (298)

Inhibition of TRPM7 suppresses cell proliferation of colon adenocarcinoma in vitro and induces hypomagnesemia in vivo without affecting azoxymethane-induced early colon cancer in mice

Cell Communication and Signaling, 2017
Magnesium (Mg2+) is an essential cation implicated in carcinogenesis, solid tumor progression and metastatic potential. The Transient Receptor Potential Melastatin Member 7 (TRPM7) is a divalent ion channel involved in cellular and systemic Mg2 ...
Junhao Huang, H. Furuya, Malika Faouzi, Zheng Zhang, Mahealani K. Monteilh-Zoller, Kelly Galbraith Kawabata, F. D. Horgen, T. Kawamori, R. Penner, A. Fleig   +9 more
semanticscholar   +1 more source

Black Raspberries Enhance Natural Killer Cell Infiltration into the Colon and Suppress the Progression of Colorectal Cancer

Frontiers in Immunology, 2017
Natural killer (NK) cells are an essential component of innate immunity against cancer development. Many studies have been conducted to evaluate immune-modulating effects using dietary compounds.
Pan Pan, Siwen Kang, Youwei Wang, Ka Liu, Kiyoko Oshima, Yi-Wen Huang, Jianying Zhang, Martha Yearsley, Jianhua Yu, Jianhua Yu, Li-Shu Wang   +10 more
doaj   +1 more source

Does ursodeoxycholic acid change the proliferation of the colorectal mucosa? A randomized, placebo-controlled study [PDF]

, 2003
Background: In animal models ursodeoxycholic acid (UDCA) showed a chemoprotective effect against colon cancer. To explain this, a reduced proliferation of the colorectal mucosal proliferation was suggested.
Diebold, J., Göke, B., Hay, U., Marsteller, I., Ochsenkühn, Thomas, Paumgartner, Gustav, Sackmann, M.   +6 more
core   +1 more source

Genomic variants in mouse model induced by azoxymethane and dextran sodium sulfate improperly mimic human colorectal cancer

Scientific Reports, 2017
Mouse model induced by azoxymethane (AOM) and dextran sodium sulfate (DSS) is generally accepted as an ideal object to study on the carcinogenesis mechanisms of human colorectal cancer (CRC).
Qingfei Pan, Xiaomin Lou, Ju Zhang, Yinghui Zhu, Fuqiang Li, Q. Shan, Xianwei Chen, Yingying Xie, Siyuan Su, Hanfu Wei, Liang Lin, Lin Wu, Siqi Liu   +12 more
semanticscholar   +1 more source

Carbohydrate Digestibility Predicts Colon Carcinogenesis in Azoxymethane-Treated Rats

Nutrition and Cancer, 2006
The purpose of this study was to compare the effect of carbohydrate structure and digestibility on azoxymethane (AOM)-induced colon carcinogenesis. Five groups of male Fischer 344 rats each comprising 30 animals were injected with AOM and fed a high-fat diet with 15% of various carbohydrates.
Jacobsen, Helene, Poulsen, Morten, Dragsted, Lars Ove, Ravn-Haren, Gitte, Meyer, Otto, Lindecrona, Rikke Hvid   +5 more
openaire   +2 more sources

EFEK PEMBERIAN EKSTRAK DAUN Carica pubescens TERHADAP JUMLAH LIMFOSIT TIKUS Sprague dawley YANG DIINDUKSI AZOXYMETHANE : STUDI DI LABORATORIUM PENELITIAN DAN PENGUJIAN TERPADU 4 UNIVERSITAS GADJAH MADA

Jurnal Kedokteran Diponegoro, 2019
Latarbelakang: Inflamasi merupakan salah satu faktor yang berperan penting dalam patofisiologi kanker kolorektal. Daun Carica pubescens yang mengandung flavonoid berpotensi sebagai agen preventif kanker kolorektal.
Maharani Shofa Yudina, Ainun Rahmasari Gumay, Muflihatul Muniroh   +2 more
doaj   +1 more source

Gum arabic and red propolis protecteting colorectal preneoplastic lesions in a rat model of azoxymethane [PDF]

Acta Cirúrgica Brasileira, 2019
Purpose: To evaluate red propolis, gum arabic and L-lysine activity on colorectal preneoplastic lesions induced by azoxymethane (AOM). Methods: The study featured 4 control groups (I-IV) and 4 experimental groups (V-VIII), totaling 48 rats. Once a week
Vanessa Nogueira Lages Braga, Camila de Carvalho Juanes, Hélio de Souza Peres Júnior, José Robson de Sousa, Bruno Coêlho Cavalcanti, Francisco Vagnaldo Fechine Jamacaru, Telma Leda Gomes de Lemos, Conceição Aparecida Dornelas   +7 more
doaj   +1 more source

Polyethylene glycol, unique among laxatives, suppresses aberrant crypt foci, by elimination of cells. [PDF]

, 2006
OBJECTIVE: Polyethylene glycol (PEG), an osmotic laxative, is a potent inhibitor of colon cancer in rats. In a search for the underling mechanisms, the hypothesis that fecal bulking and moisture decrease colon carcinogenesis was tested.
Corpet, Denis E., Parnaud, Géraldine, Taché, Sylviane, Van Beek, Erik   +3 more
core   +3 more sources

Effect of vitamin C on azoxymethane (AOM)/dextran sulfate sodium (DSS)-induced colitis-associated early colon cancer in mice

Nutrition Research and Practice, 2018
BACKGROUND/OBJECTIVES The objective of this study was to investigate the effects of vitamin C on inflammation, tumor development, and dysbiosis of intestinal microbiota in an azoxymethane (AOM)/dextran sulfate sodium (DSS)-induced inflammation-associated
Hee-Jin Jeon, Yiseul Yeom, Yoo-Sun Kim, Eunju Kim, Jae-Ho Shin, P. Seok, M. Woo, Yuri Kim   +7 more
semanticscholar   +1 more source

A20 Restricts NOS2 Expression and Intestinal Tumorigenesis in a Mouse Model of Colitis-Associated Cancer

Gastro Hep Advances, 2023
Background and Aims: Colon cancer can occur sporadically or in the setting of chronic inflammation, such as in patients with inflammatory bowel disease.
David W. Basta, Mandy Vong, Adolat Beshimova, Brooke N. Nakamura, Iulia Rusu, Michael G. Kattah, Ling Shao   +6 more
doaj   +1 more source