Results 131 to 140 of about 16,733 (229)

Aztreonam-avibactam: an option against carbapenem-resistant Enterobacterales with emerging resistance

Precision Clinical Medicine, 2022
Wu, Shikai, Zong, Zhiyong
openaire   +2 more sources

Incidence of hospital-acquired infections due to carbapenem-resistant Enterobacterales and Pseudomonas aeruginosa in critically ill patients in Italy: a multicentre prospective cohort study [PDF]

BackgroundCarbapenem-Resistant Gram-Negative Bacteria, including Carbapenem-Resistant Enterobacterales (CRE) and Carbapenem-Resistant Pseudomonas aeruginosa (CRPA), are common causes of infections in intensive care units (ICUs) in Italy.ObjectiveThis ...
Aceto R., Ambretti S., Antonelli M., Brazzi L., Buffoli F., Cappanera S., Carelli S., Casari E., Casarotta E., Cattaneo S., Cavallero A., Cecconi M., Cortegiani A., Cuffaro R., Curtoni A., Cutuli S. L., Dalfino L., De Pascale G., Degl'Innocenti L., Di Biase F., Donati A., Fasano F. R., Fasciana T., Ferrari F., Foti G., Frattari A., Fumagalli R., Gherardi G., Giani T., Giarratano A., Girardis M., Gottin L., Guerrero F. A., Ippolito M., Mariottini A., Mattei A., Mazzariol A., Merola G., Milazzo M., Monti G., Montini L., Montrucchio G., Mosca A., Muroni A., Pasero D., Picciafuochi F., Ricciardi R., Rinaldi M., Rona R., Rubino S., Savini V., Sensi E., Serio L., Servillo G., Spanu T., Stufano M., Taiana M., Tanzarella E. S., Tiri B., Vargas M., Viaggi B., Viale P., Vidal Pereira M. A., Vismara C., Vittorielli E.   +64 more
core   +4 more sources

The coexistence of three bla_KPC-2 genes on an IncF/IncR plasmid in ST11 Klebsiella pneumoniae [PDF]

, 2018
Background: We found three copies of blaKPC-2 on a plasmid of a Klebsiella pneumoniae strain and report the findings here.Methods: A carbapenem-resistant K. pneumoniae clinical strain, SCEC020002, was subjected to whole genome sequencing using both short-
Feng, Yu, Liu, Lu, McNally, Alan, Zong, Zhiyong   +3 more
core   +1 more source

Evaluation of the in vitro efficacy of antimicrobials against Enterobacterales with multiple carbapenemase enzymes

Iranian Journal of Microbiology
Background and Objectives: High-dose of carbapenems and combination therapies with new β-lactam/β-lactamase inhibitors and polymyxin B/tigecycline have been considered for treatment of carbapenem resistant Enterobacterales infection.
Reena Rajan, Gopinathan Sasikala
doaj   +1 more source

Pacific RxTracts - March 2025 [PDF]

Articles Naloxone Extended-Release System Discovered at the University of the Pacific FDA Approval for Unresectable/ Metastatic Breast Cancer Journavx (Suzetrigine): A New Era in Pain Management New Treatment Approved for Congenital Adrenal Hyperplasia
Pacific RxTracts
core   +1 more source

Carbapenem-Resistant Enterobacteriaceae in Urinary Tract Infections: From Biological Insights to Emerging Therapeutic Alternatives [PDF]

Urinary tract infections (UTIs) are the second most frequent type of infection observed in clinical practice. Gram-negative Enterobacteriaceae are common pathogens in UTIs.
Abate M., Arcaniolo D., Aveta A., Barone B., Bologna E., Cilio S., Cirillo L., Crocetto F., Di Filippo I., Di Mauro E., Ditonno F., Franco A., Fusco G. M., La Rocca R., Licari L. C., Manfredi C., Napolitano L., Pandolfo S. D., Passaro F., Pinchera B.   +19 more
core   +1 more source

In vitro activity of aztreonam in combination with relebactam against gram-negative pathogens producing various serine and metallo-β-lactamases

Journal of Global Antimicrobial Resistance
Objectives: Infections caused by carbapenemase-producing Gram-negative pathogens have become a significant global public health challenge due to limited treatment options.
Kengo Hayashi, Masahiro Suzuki, Yoshikazu Ishii, Yasufumi Matsumura, Kazuaki Matsumoto, Sho Saito, Yohei Doi   +6 more
doaj   +1 more source

Spotlight commentary: Treatment of multidrug‐resistant Gram‐negative infections in the era of growing antimicrobial resistance

British Journal of Clinical Pharmacology, Volume 91, Issue 9, Page 2485-2489, September 2025.
Luka Bielen, Andro Vujević, Luka Csenar
wiley   +1 more source

Aztreonam-Avibactam Combination Restores Susceptibility of Aztreonam in Dual-Carbapenemase-Producing Enterobacteriaceae [PDF]

Antimicrobial Agents and Chemotherapy, 2018
Ka Lip Chew, Michelle K. L. Tay, Bernadette Cheng, Raymond T. P. Lin, Sophie Octavia, Jeanette W. P. Teo   +5 more
openaire   +2 more sources

Comparison of agar-based methodologies to broth disc elution for the detection of aztreonam susceptibility in the presence of ceftazidime-avibactam

Microbiology Spectrum
The combination of aztreonam and ceftazidime-avibactam is a proven treatment option for infections caused by metallo-beta-lactamase (MBL)-expressing gram-negative organisms. Restoration of aztreonam susceptibility in the presence of ceftazidime-avibactam
Teslin S. Sandstrom, Andra Banete, Alice Kanyua, Kevin M. Davis, Susan M. Poutanen   +4 more
doaj   +1 more source