Results 81 to 90 of about 9,189 (185)

In Vitro Activities and Inoculum Effects of Cefiderocol and Aztreonam-Avibactam against Metallo-β-Lactamase-Producing Enterobacteriaceae

Microbiology Spectrum, 2023
The prevalence of infections caused by carbapenem-resistant Enterobacteriaceae is increasing worldwide. Currently, therapeutic options for metallo-β-lactamase (MBL)-producing Enterobacteriaceae remain limited.
Yu-Shan Huang, Pao-Yu Chen, Pei-Chun Chou, Jann-Tay Wang   +3 more
openaire   +3 more sources

Comparative analysis of the effects of aztreonam combined with four β-lactamase inhibitors against carbapenem-resistant Enterobacterales

Microbiology Spectrum
Carbapenem-resistant Enterobacterales (CRE) pose a global public health threat due to multidrug resistance and treatment failure. This study evaluated the effects of aztreonam combined with four β-lactamase inhibitors (avibactam, clavulanic acid ...
Qing Meng, Chao Xu, Wujiao Li, Kunling Shen, Xiuhui Huang, Xiaoying Fu, Lintao Zhou, Yunsheng Chen, Fupin Hu, Heping Wang   +9 more
doaj   +1 more source

Bloodstream Infection Caused by Carbapenemase‐Producing Enterobacterales in a Tertiary Hospital of Colombia: A 6 Year Retrospective Study

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2026, Issue 1, 2026.
Background The global spread of carbapenemase‐producing Enterobacterales (CPE) has emerged as a significant public health challenge. However, epidemiological studies on CPE infections in Latin America remain scarce. This study aims to characterize bloodstream infections (BSIs) caused by CPE at a tertiary hospital over a 6‐year period and analyze the ...
Juan David Cáceres-González, Jorge Álvarez, Lorena Matta-Cortés, Ernesto Martínez-Buitrago, Johann A. Ospina-Galindez, Claudia C. Paredes-Amaya, Bishnu P. Marasini   +6 more
wiley   +1 more source

In Vitro Activity of Aztreonam-Avibactam against Enterobacteriaceae and Pseudomonas aeruginosa Isolated by Clinical Laboratories in 40 Countries from 2012 to 2015

, 2017
The combination of the monobactam aztreonam and the non-β-lactam β-lactamase inhibitor avibactam is currently in clinical development for the treatment of serious infections caused by metallo-β-lactamase (MBL)-producing Enterobacteriaceae
Boudewijn L. M. de Jonge, Krystyna M. Kazmierczak, Daniel F. Sahm, Patricia A. Bradford, James A. Karlowsky, Meredith A. Hackel   +5 more
core   +1 more source

Distribution and Drug‐Resistance Analysis of Uropathogens in Urinary Tract Infections

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2026, Issue 1, 2026.
Background Urinary tract infections (UTIs) are a major global health concern with increasing antimicrobial resistance. Regional data on pathogen distribution and resistance patterns are essential for guiding empirical therapy. This study aimed to investigate the distribution and antimicrobial resistance profiles of UTI pathogens in Shanghai, China, and
Weiyi Wu, Qiong Wu, Wenying Zhong, Lizhong Han, Mohsin Khurshid   +4 more
wiley   +1 more source

Fatal Emphysematous Tonsillopharyngitis With Laryngocele Involvement Revealing Acute Myeloid Leukemia M5 Subtype: A Previously Undescribed Presentation

Case Reports in Oncological Medicine, Volume 2026, Issue 1, 2026.
Emphysematous infections in the tonsillopharyngeal area are exceptionally unique; this type of infection occurs in immunocompromised patients. Extramedullary disease can occur in acute myeloid leukemia (AML), but oropharyngeal involvement is rare and diagnostically challenging.
Somaya Al Kiswani, Mohammed Abduljabbar Abed, Hossam Salameh, Muna Shahwan, Omar Sawafta, Suhaib Eid, Fatena A. H. Ajlouni, Abdullah Nofal, Lipi Buch   +8 more
wiley   +1 more source

Activity of aztreonam-avibactam and ceftazidime-avibactam against β-lactamase-producing enterobacterales Isolates from United States hospitals

Journal of Global Antimicrobial Resistance
Objectives: Enterobacterales isolates producing β-lactamases are widespread and threaten the use of β-lactams. This study evaluated the activity of aztreonam-avibactam and comparator antimicrobial agents against Enterobacterales isolates producing common
Lalitagauri M Deshpande, Timothy B Doyle, Helio S Sader, Mariana Castanheira   +3 more
doaj   +1 more source

Cucumber Production System as a Reservoir for Clinically Important Extended‐Spectrum Beta‐Lactamase‐ and AmpC Beta‐Lactamase‐Producing Escherichia coli and Klebsiella pneumoniae Strains

International Journal of Food Science, Volume 2026, Issue 1, 2026.
This study evaluated clinically significant extended‐spectrum β‐lactamase (ESBL)‐ and AmpC β‐lactamase (AmpC)‐ producing Escherichia coli and Klebsiella pneumoniae in a cucumber production system, focusing on their potential sources and public health implications.
Manana Dlangalala, Stacey Duvenage, Erika Margarete Du Plessis, Lise Korsten, Muhammad Asif Zahoor   +4 more
wiley   +1 more source

Ceftazidime-avibactam/aztreonam combination synergy against carbapenem-resistant Gram-negative isolates: In vitro study

Current Medicine Research and Practice
Background: The ceftazidime-avibactam combination is able to inhibit ESBLs, AmpCs and Class A carbapenemases and has been recommended for the treatment of complicated UTIs and ventilator-associated bacterial pneumonia.
Reena Rajan, A V Raghavendra Rao, Mathavi Suresh Kumar   +2 more
doaj   +1 more source

Molecular Characterization and Antibiotic Resistance of Broad‐Spectrum β‐Lactamase‐Producing Enterobacterales in Urinary Tract Infections in Libreville, Gabon

International Journal of Microbiology, Volume 2026, Issue 1, 2026.
Background The effectiveness of antibiotic therapy for urogenital tract infections (UTIs) is increasingly compromised by the global dissemination of extended‐spectrum β‐lactamase‐producing Enterobacterales (ESβL‐En). This study aimed to assess the involvement of broad‐spectrum β‐lactamase‐producing Enterobacterales (BSβL‐En) in UTIs and to establish ...
Jean Fabrice Yala, Ornella Zong Minko, Rolande Mabika Mabika, Franck Mounioko, Elvire Anita Mbongo-Kama, Annicet Clotaire Dikoumba, Alain Souza, Shweta Negi   +7 more
wiley   +1 more source