Results 91 to 100 of about 16,733 (229)

Distribution and Drug‐Resistance Analysis of Uropathogens in Urinary Tract Infections

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2026, Issue 1, 2026.
Background Urinary tract infections (UTIs) are a major global health concern with increasing antimicrobial resistance. Regional data on pathogen distribution and resistance patterns are essential for guiding empirical therapy. This study aimed to investigate the distribution and antimicrobial resistance profiles of UTI pathogens in Shanghai, China, and
Weiyi Wu, Qiong Wu, Wenying Zhong, Lizhong Han, Mohsin Khurshid   +4 more
wiley   +1 more source

Antimicrobial Activity of Aztreonam-Avibactam and Comparator Agents Tested against Contemporary (2016) Clinical Enterobacteriaceae Isolates [PDF]

Open Forum Infectious Diseases, 2017
Abstract Background Avibactam (AVI) is a non-β-lactam β-lactamase (BL) inhibitor that inhibits Ambler class A, C, and some class D enzymes (eg, ESBL, KPC, and AmpC), and aztreonam (ATM) is a monobactam stable to hydrolysis by metallo-β-lactamases (MBL).
Sader, Helio S, Mendes, Rodrigo E, Shortridge, Dee, Flamm, Robert K, Castanheira, Mariana   +4 more
openaire   +1 more source

Carbapenemase-producing organisms: a global scourge [PDF]

, 2018
The dramatic increase in the prevalence and clinical impact of infections caused by bacteria producing carbapenemases is a global health concern.
Bonomo, Robert A, Burd, Eileen M, Conly, John, Limbago, Brandi M, Poirel, Laurent, Segre, Julie A, Westblade, Lars F   +6 more
core  

Extremely drug resistant E. coli and K. pneumoniae : novel approaches against their spread and related infections [PDF]

, 2022
Antibiotic resistance in Enterobacteriaceae is a well-established hindrance and the spread of pathogenic high-risk clones harboring extended-spectrum -lactamases (ESBLs) and carbapenemases is posing a global health challenge, due to very less treatment ...
Camporeale, Angela
core   +1 more source

Fatal Emphysematous Tonsillopharyngitis With Laryngocele Involvement Revealing Acute Myeloid Leukemia M5 Subtype: A Previously Undescribed Presentation

Case Reports in Oncological Medicine, Volume 2026, Issue 1, 2026.
Emphysematous infections in the tonsillopharyngeal area are exceptionally unique; this type of infection occurs in immunocompromised patients. Extramedullary disease can occur in acute myeloid leukemia (AML), but oropharyngeal involvement is rare and diagnostically challenging.
Somaya Al Kiswani, Mohammed Abduljabbar Abed, Hossam Salameh, Muna Shahwan, Omar Sawafta, Suhaib Eid, Fatena A. H. Ajlouni, Abdullah Nofal, Lipi Buch   +8 more
wiley   +1 more source

Pharmacokinetics/pharmacodynamics of a β-lactam and β-lactamase inhibitor combination: a novel approach for aztreonam/avibactam [PDF]

Journal of Antimicrobial Chemotherapy, 2015
The combination of aztreonam/avibactam has promising activity against MDR Gram-negative pathogens producing metallo-β-lactamases (MBLs), such as New Delhi MBL-1. Pharmacokinetic (PK)/pharmacodynamic (PD) understanding of this combination is critical for optimal clinical dose selection.
Renu, Singh, Aryun, Kim, M Angela, Tanudra, Jennifer J, Harris, Robert E, McLaughlin, Sara, Patey, John P, O'Donnell, Patricia A, Bradford, Ann E, Eakin   +8 more
openaire   +2 more sources

Resistance to aztreonam-avibactam among clinical isolates of E. coli is primarily mediated by altered penicillin binding protein 3 and impermeability.

International Journal of Antimicrobial Agents
Herein, we investigated decreased susceptibility (DS; MICs 0.25-4 mg/L) and resistance (R; MICs >4 mg/L) to aztreonam-avibactam (ATM-AVI). Contemporary non-replicate clinical isolates of carbapenemase-producing Escherichia coli (n=90) (CP-EC) and ESBL ...
C. Tellapragada, Mohammad Razavi, Pol Saludes Peris, Patrik Jonsson, Martin Vondracek, C. Giske   +5 more
semanticscholar   +1 more source

Cucumber Production System as a Reservoir for Clinically Important Extended‐Spectrum Beta‐Lactamase‐ and AmpC Beta‐Lactamase‐Producing Escherichia coli and Klebsiella pneumoniae Strains

International Journal of Food Science, Volume 2026, Issue 1, 2026.
This study evaluated clinically significant extended‐spectrum β‐lactamase (ESBL)‐ and AmpC β‐lactamase (AmpC)‐ producing Escherichia coli and Klebsiella pneumoniae in a cucumber production system, focusing on their potential sources and public health implications.
Manana Dlangalala, Stacey Duvenage, Erika Margarete Du Plessis, Lise Korsten, Muhammad Asif Zahoor   +4 more
wiley   +1 more source

In Vitro Activities and Inoculum Effects of Cefiderocol and Aztreonam-Avibactam against Metallo-β-Lactamase-Producing Enterobacteriaceae

Microbiology Spectrum, 2023
The prevalence of infections caused by carbapenem-resistant Enterobacteriaceae is increasing worldwide. Currently, therapeutic options for metallo-β-lactamase (MBL)-producing Enterobacteriaceae remain limited.
Yu-Shan Huang, Pao-Yu Chen, Pei-Chun Chou, Jann-Tay Wang   +3 more
openaire   +3 more sources

Comparative analysis of the effects of aztreonam combined with four β-lactamase inhibitors against carbapenem-resistant Enterobacterales

Microbiology Spectrum
Carbapenem-resistant Enterobacterales (CRE) pose a global public health threat due to multidrug resistance and treatment failure. This study evaluated the effects of aztreonam combined with four β-lactamase inhibitors (avibactam, clavulanic acid ...
Qing Meng, Chao Xu, Wujiao Li, Kunling Shen, Xiuhui Huang, Xiaoying Fu, Lintao Zhou, Yunsheng Chen, Fupin Hu, Heping Wang   +9 more
doaj   +1 more source