Results 51 to 60 of about 14,976,308 (290)

HLA-DR expression in melanoma: from misleading therapeutic target to potential immunotherapy biomarker

Frontiers in Immunology
Since the advent of anti-PD1 immune checkpoint inhibitor (ICI) immunotherapy, cutaneous melanoma has undergone a true revolution with prolonged survival, as available 5-year updates for progression-free survival and overall survival demonstrate a durable
Karim Amrane, Karim Amrane, Coline Le Meur, Benjamin Besse, Benjamin Besse, Patrice Hemon, Pierre Le Noac’h, Pierre Le Noac’h, Olivier Pradier, Christian Berthou, Christian Berthou, Ronan Abgral, Ronan Abgral, Arnaud Uguen, Arnaud Uguen   +14 more
doaj   +1 more source

FEATURES OF THE IMMUNE RESPONSE DURING VIRAL INFECTION

Инфекция и иммунитет, 2015
The aim of the investigation was to select using cluster analysis and comparatively characterize immune disorders types in acute and chronic viral infections.
G. A. Borisov, A. A. Savchenko, Igor V. Kudryavtsev   +2 more
doaj   +1 more source

REGULATION OF PERIPHERAL B-LYMPHOCYTE DIFFERENTIATION IN RECURRENT MISCARRIAGE

Медицинская иммунология, 2021
The important role of immune disorders in recurrent miscarriage has been proven. Clarification of the character of B-lymphocyte differentiation and its regulation factors in women with threatened miscarriage and recurrent miscarriage in history is an ...
A. I. Malyshkina, N. Yu. Sotnikova, A. V. Kust, D. N. Voronin   +3 more
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Number of T- and B-lymphocytes and their functional activity in the blood of common carps aff ected by Aeromonosis, and in the treatment of probiotic Enteronormin

Науковий вісник ветеринарної медицини, 2020
Fish bacterial infectious diseases are a signifi cant problem for aquaculture, often leading to massive fi sh deaths and signifi cant economic losses. For fi sh treatment often used antibacterial drugs: nitrofuran, antibiotics, feed antibiotics, as well ...
Solopova Kh., Vishchur O.
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Influence of Bacillus anthracis 34F₂ Sterne Antigen Preparations in Combination with Cobaltarabinogalactan on the Subpopulation Structure of B-lymphocytes (Communication 2)

Эпидемиология и вакцинопрофилактика, 2015
Study of Bacillus anthracis 34F2 Sterne antigenic preparation S-2 and its combined use with nanostructured cobalt-arabinogalaktan (Со-АG) is presented. The ability of these preparations to stimulate proliferation and differentiation of B-lymphocytes is ...
V. V. Voytkova, V. I. Dubrovina, S. V. Lukyanov, O. V. Yuryeva, O. B. Kol’Esnikova, K. M. Korytov, G. P. Aleksandrova, V. P. Iljin, S. V. Balakhonov   +8 more
doaj   +1 more source

CD5-Positive B Lymphocytes after Kidney Transplantation

Diagnostics, 2021
Kidney transplantation is the treatment of choice for end-stage kidney diseases. Unfortunately, kidney allograft recipients rarely develop tolerance or accommodation and require life-long immunosuppression.
Maciej Zieliński, Agnieszka Tarasewicz, Hanna Zielińska, Magdalena Jankowska, Justyna Sakowska, Anna Dukat-Mazurek, Grażyna Moszkowska, Bolesław Rutkowski, Alicja Dębska-Ślizień, Piotr Trzonkowski   +9 more
doaj   +1 more source

B Lymphocytes: Development, Tolerance, and Their Role in Autoimmunity—Focus on Systemic Lupus Erythematosus

Autoimmune Diseases, 2013
B lymphocytes are the effectors of humoral immunity, providing defense against pathogens through different functions including antibody production. B cells constitute approximately 15% of peripheral blood leukocytes and arise from hemopoietic stem cells ...
G. Tobón, J. Izquierdo, C. Cañas
semanticscholar   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source