Results 81 to 90 of about 637,016 (303)
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen+12 more
wiley +1 more source
Understanding and measuring mechanical signals in the tumor stroma
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz+3 more
wiley +1 more source
Immunofluorescent Detection of Human B Cell Alloantigens on S-Ig-Positive Lymphocytes and Epidermal Langerhans Cells [PDF]
Georg Stingl+3 more
openalex +1 more source
Novel mAbs could detect cancer‐associated membrane proteins on various type of pancreatic ductal adenocarcinomas (PDAC) by flow cytometry with viable PDAC cells and by immunohistochemistry with PDAC tissues. Results of protein expression were substantiated by mRNA expression by The Cancer Genome Atlas.
Takashi Nakano+16 more
wiley +1 more source
Estrogen is very important to the differentiation of B lymphocytes; B lymphopoiesis induced by OVX was supposedly involved in osteoporosis. But the effects of B lymphocytes on the osteogenic differentiation of bone mesenchymal stem cells (BMSCs) are not ...
Mengxue Pan+14 more
doaj +1 more source
Histological examination of the palatine tonsils in chronic tonsillitis
The article is devoted to the problem of chronic tonsillitis. The aim of the study was to assess changes in the morphofunctional state of the palatine tonsils in chronic inflammation. The study presents comparative data of immunohistochemical examination
V. T. Pal’chun+3 more
doaj +1 more source
Receptors for Immunoglobulin on B Lymphocytes and Cells of a Cultured Plasma Cell Tumor [PDF]
Martin J. Cline+3 more
openalex +1 more source
IDMF is a derivative of dimethyl fumarate (DMF) with a unique therapeutic potential at the intersection of psoriasis and multiple sclerosis. Here, we demonstrate that it compares favorably with DMF and its other derivatives, such as Diroximel, in the zebrafish, microglia, and lymphocyte models.
Yulin He+5 more
wiley +1 more source
Greater Sensitivity to Inhibition by Anti-Immunoglobulin of Splenic than of Bone Marrow B-Lymphocytes [PDF]
J J Mond, G. J. Thorbecke
openalex +1 more source
Twenty-six patients with active and inactive sarcoidosis were studied. Surface immunofluorescence techniques with polyvalent and monospecific antisera after resynthesis of intrinsic Ig, were employed to determine the number of B cells. The peroxidase positive cells were not included in the count.
COLOMBATTI M+6 more
openaire +2 more sources