Results 21 to 30 of about 4,686 (216)

Clinical and epidemiological picture of B pertussis and B parapertussis infections after introduction of acellular pertussis vaccines [PDF]

Archives of Disease in Childhood, 2003
To investigate the clinical picture and frequency of Bordetella pertussis and B parapertussis infections after introduction of acellular pertussis (acP) vaccines in Germany.Prospective surveillance for B pertussis and B parapertussis in 14 144 toddlers. Pertussis vaccination coverage was 86%, either with acP (75%) or whole cell pertussis (wcP) vaccine (
J G, Liese, C, Renner, S, Stojanov, B H, Belohradsky   +3 more
openaire   +2 more sources

Inefficient Toll-like receptor-4 stimulation enables Bordetella parapertussis to avoid host immunity.

PLoS ONE, 2009
The recognition of bacterial lipopolysaccharide (LPS) by host Toll-like receptor (TLR)4 is a crucial step in developing protective immunity against several gram negative bacterial pathogens. Bordetella bronchiseptica and B.
Daniel N Wolfe, Anne M Buboltz, Eric T Harvill   +2 more
doaj   +1 more source

Outer Membrane Vesicles as a Versatile Platform for Vaccine Development: Engineering Strategies, Applications and Challenges. [PDF]

J Extracell Vesicles
ABSTRACT Outer membrane vesicles (OMVs) are nanosized vesicles naturally secreted by Gram‐negative bacteria and represent a promising platform for vaccine development. OMVs possess inherent immunostimulatory properties due to the presence of pathogen‐associated molecular patterns (PAMPs), providing self‐adjuvanting capabilities and the ability to ...
Garling A, Auvray F, Epardaud M, Oswald É, Branchu P.   +4 more
europepmc   +2 more sources

Bordetella pertussis, the Causative Agent of Whooping Cough, Evolved from a Distinct, Human-Associated Lineage of B. bronchiseptica.

PLoS Pathogens, 2005
Bordetella pertussis, B. bronchiseptica, B. parapertussis(hu), and B. parapertussis(ov) are closely related respiratory pathogens that infect mammalian species. B. pertussis and B.
Dimitri A Diavatopoulos, Craig A Cummings, Leo M Schouls, Mary M Brinig, David A Relman, Frits R Mooi   +5 more
doaj   +2 more sources

Characterization of Post-Translational Modifications and Cytotoxic Properties of the Adenylate-Cyclase Hemolysin Produced by Various Bordetella pertussis and Bordetella parapertussis Isolates

Toxins, 2017
Bordetella pertussis and Bordetella parapertussis are the causal agents of whooping cough in humans. They produce diverse virulence factors, including adenylate cyclase-hemolysin (AC-Hly), a secreted toxin of the repeat in toxins (RTX) family with ...
Valérie Bouchez, Thibaut Douché, Mélody Dazas, Sophie Delaplane, Mariette Matondo, Julia Chamot-Rooke, Nicole Guiso   +6 more
doaj   +1 more source

The type III secreted protein BspR regulates the virulence genes in Bordetella bronchiseptica. [PDF]

PLoS ONE, 2012
Bordetella bronchiseptica is closely related with B. pertussis and B. parapertussis, the causative agents of whooping cough. These pathogenic species share a number of virulence genes, including the gene locus for the type III secretion system (T3SS ...
Jun Kurushima, Asaomi Kuwae, Akio Abe
doaj   +1 more source

Membrane vesicles derived from Bordetella bronchiseptica: Active constituent of a new vaccine against infections caused by this pathogen [PDF]

, 2018
Bordetella bronchiseptica, a Gram-negative bacterium, causes chronic respiratory tract infections in a wide variety of mammalian hosts, including humans (albeit rarely).
Bartel, Erika Belén, Bottero, Daniela, Gaillard, María Emilia, Hozbor, Daniela Flavia, Vercellini, María Clara, Zurita, Maria Eugenia   +5 more
core   +2 more sources

Increase in pertussis cases along with high prevalence of two emerging genotypes of Bordetella pertussis in Perú, 2012 [PDF]

, 2016
As has occurred in many regions worldwide, in 2012 the incidence of pertussis increased in Perú. This epidemiologic situation has been associated with a waning vaccine-induced immunity and the adaptation of Bordetella pertussis to vaccine-induced ...
Bailon, H, Hozbor, Daniela Flavia, León-Janampa, N, Padilla, C.   +3 more
core   +3 more sources

Differentiation of Bordetella pertussis, B. parapertussis, and B. bronchiseptica by Whole-Cell Protein Electrophoresis and Fatty Acid Analysis [PDF]

International Journal of Systematic Bacteriology, 1995
One-dimensional sodium dodecyl sulfate-polyacrylamide gel electrophoresis of whole-cell proteins and gas-liquid chromatography of cellular fatty acids were used to determine chemotaxonomic characteristics of strains belonging to Bordetella pertussis, Bordetella parapertussis, and Bordetella bronchiseptica.
M. VANCANNEYT, P. VANDAMME, K. KERSTERS
openaire   +1 more source

Chromosome-Borne Class A BOR-1 β - Lactamase of Bordetella bronchiseptica and Bordetella parapertussis [PDF]

Antimicrobial Agents and Chemotherapy, 2005
ABSTRACT A narrow-spectrum clavulanic acid-inhibited class A β-lactamase, BOR-1, was identified in a Bordetella bronchiseptica clinical isolate. It shared 45% amino acid identity with L-2 from Stenotrophomonas maltophilia .
Marie-Frédérique, Lartigue, Laurent, Poirel, Nicolas, Fortineau, Patrice, Nordmann   +3 more
openaire   +2 more sources