Results 61 to 70 of about 4,686 (216)

Structural and functional specialization of Bordetella pertussis DsbA for pertussis toxin folding

Protein Science, Volume 35, Issue 1, January 2026.
Abstract Disulphide bonds (Dsbs) are essential for the folding, stability, and function of many secreted and membrane‐associated proteins in bacteria. In Gram‐negative species, these bonds are introduced by the Dsb enzyme family, with DsbA acting as the primary thiol oxidase.
Stephanie Penning, Lachlan Mitchell, Yaoqin Hong, Taylor Cunliffe, Pramod Subedi, Geqing Wang, Lilian Hor, Makrina Totsika, Jason J. Paxman, Begoña Heras   +9 more
wiley   +1 more source

Inverse relationship between genetic diversity and epigenetic complexity [PDF]

, 2008
Early studies of molecular evolution revealed a correlation between genetic distance and time of species divergence. This observation provoked the molecular clock hypothesis and in turn the ‘Neutral Theory’, which however remains an ...
Shi Huang
core   +3 more sources

Causes and Seasonality of Upper Respiratory Infections in Adults in Lesotho (2021–2022) (CORIAL)

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2026, Issue 1, 2026.
Background Upper respiratory tract infections cause morbidity and a high burden on healthcare systems worldwide, especially in low‐ and lower middle‐income countries. Recent studies throughout Africa indicate seasonal patterns that deviate from those previously described in settings with temperate climates.
Nikita Sass, Linda Janita Wüthrich, Flor Lucia Gonzalez Fernandez, Emmanuel Firima, Tracy R. Glass, Moniek Bresser, Josephine Muhairwe, Bulemba Katende, Mamello Molatelle, Irene Ayakaka, Daniel Goldenberger, Kinga Feuz, Pascal Schlaepfer, Klaus Reither, Niklaus D. Labhardt, Mamunur Rahman Malik   +15 more
wiley   +1 more source

Role of phosphoglucomutase of Bordetella bronchiseptica in lipopolysaccharide biosynthesis and virulence [PDF]

, 2000
The phosphoglucomutase (PGM)-encoding gene of Bordetella bronchiseptica is required for lipopolysaccharide (LPS) biosynthesis. An insertion mutant of the wild-type B.
West, Nicholas P., Jungnitz, Heidrun, Fitter, John T., McArthur, Jason D., Guzman, Carlos A., Walker, Mark J.   +5 more
core   +1 more source

Improvement of Mycoplasma pneumoniae–Associated Acute Cerebellar Ataxia and Possible Encephalopathy After Intravenous Immunoglobulin

Case Reports in Infectious Diseases, Volume 2026, Issue 1, 2026.
Mycoplasma pneumoniae (M. pneumoniae) can cause acute postinfectious cerebellar ataxia and encephalitis/encephalopathy. Although ataxia can be self‐limited, prolonged duration of symptoms and long‐term neurological sequelae that persist for months or more are associated with both conditions.
Kathleen Ruff, Miltiadis Douvoyiannis, Priya Gusain   +2 more
wiley   +1 more source

Bordetella Type III Secretion Injectosome and Effector Proteins

Frontiers in Cellular and Infection Microbiology, 2020
Pertussis, also known as whooping cough, is a resurging acute respiratory disease of humans primarily caused by the Gram-negative coccobacilli Bordetella pertussis, and less commonly by the human-adapted lineage of B. parapertussisHU.
Jana Kamanova
doaj   +1 more source

Severe Necrotizing Community‐Acquired Pneumonia and Bilateral Empyema in an Immunocompetent Patient due to Fusobacterium necrophorum

Case Reports in Pulmonology, Volume 2026, Issue 1, 2026.
Necrotizing pneumonia and empyema caused by Fusobacterium necrophorum are uncommon. The classical presentation of Lemierre′s syndrome, characterized by pharyngotonsillitis and internal jugular vein thrombosis, is not always observed, and incomplete and atypical variants can cause diagnostic uncertainty and delay in treatment.
Deborah Shefa, Aryan Shiari, Marina Antic, Buddhi P. Hatharaliyadda, Juan Vera Gomez, David Ladin, Igor Dumic, Tun-Chieh Chen   +7 more
wiley   +1 more source

Bordetella petrii Infection with Long-lasting Persistence in Human

Emerging Infectious Diseases, 2011
We report the repeated isolation of Bordetella petrii in the sputum of a 79-year-old female patient with diffuse bronchiectasis and persistence of the bacterium for >1 year.
Alain Le Coustumier, Elisabeth Njamkepo, Vincent Cattoir, Sophie Guillot, Nicole Guiso   +4 more
doaj   +1 more source

Bordetella spp. utilize the type 3 secretion system to manipulate the VIP/VPAC2 signaling and promote colonization and persistence of the three classical Bordetella in the lower respiratory tract

Frontiers in Cellular and Infection Microbiology, 2023
IntroductionBordetella are respiratory pathogens comprised of three classical Bordetella species: B. pertussis, B. parapertussis, and B. bronchiseptica. With recent surges in Bordetella spp.
Nicholas J. First, Jose Pedreira-Lopez, Manuel R. F. San-Silvestre, Katelyn M. Parrish, Xiao-Hong Lu, Monica C. Gestal   +5 more
doaj   +1 more source

Rebound of Respiratory Virus Activity and Seasonality to Pre‐Pandemic Patterns

Journal of Medical Virology, Volume 97, Issue 11, November 2025.
ABSTRACT The emergence of SARS‐CoV‐2 and the implementation of non‐pharmaceutical interventions (NPIs) profoundly disrupted the transmission dynamics of respiratory viruses, altering their epidemiology and seasonality. However, comprehensive long‐term data on these shifts and their post‐pandemic implications remain limited.
Rainer Gosert, Klaudia Naegele, Marvin Weiss, Roland Bingisser, Christian H. Nickel, Jakob Meyer, Martin Siegemund, Stefano Bassetti, Sarah Dräger, Christoph T. Berger, Fabian Franzek, Ulrich Heininger, Julia Bielicki, Hans H. Hirsch, Peter M. Keller, Maja Weisser, Nina Khanna, Sarah Tschudin‐Sutter, Karoline Leuzinger   +18 more
wiley   +1 more source