Results 201 to 210 of about 28,303 (242)

Assembly and regulation of prothrombinase complex on B16F10 melanoma cells

Thrombosis Research, 2005
A number of studies indicate that coagulation proteases play significant roles in cancer biology. Melanoma is a highly metastatic cancer, and there is evidence that thrombin contributes to this aggressive pattern. However, few studies correlate this type of cancer with formation of the prothrombinase complex, which is responsible for conversion of ...
Clarice, Kirszberg, Vivian M, Rumjanek, Robson Q, Monteiro   +2 more
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Interactions of B16F10 melanoma cells aggregated on a cellulose substrate

Journal of Cellular Biochemistry, 2006
AbstractThere is evidence that the shape of cells and their contact with a matrix direct the growth and the differentiation of both normal and cancer cells. Cells in 3D culture resemble the in vivo situation more closely than do those in conventional 2D cultures.
Hindié, M., Vayssade, M., Dufresne, M., Quéant, S., Warocquier-Clérout, R., Legeay, G., Vigneron, P., Olivier, V., Duval, J.‐l., Nagel, M.‐d.   +9 more
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Differential Distribution of B16F10 Melanoma Cells in the Liver Lobule

Pathobiology, 1988
The distribution pattern and the number of tumor cells arrested in the liver were studied in mouse livers. Mice were perfused intravascularly with a suspension of B16F10 melanoma cells. The animals were sacrificed at 0, 1, 5 and 20 min after tumor cell perfusion.
E, Hilario, F, Unda, S F, Aliño
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Shikonin Causes Non-apoptotic Cell Death in B16F10 Melanoma

Anti-Cancer Agents in Medicinal Chemistry, 2023
Background: Melanoma treatment is highly resistant to current chemotherapeutic agents. Due to its resistance towards apoptotic cell death, non-apoptotic cell death pathways are sought after. Objective: We investigated a Chinese herbal medicine, shikonin, and its effect on B16F10 melanoma cells in vitro.
Haleema, Ahmad, Megan S, Crotts, Jena C, Jacobs, Robert W, Baer, James L, Cox   +4 more
openaire   +2 more sources

Inhibition of lung homing of B16F10 by pentoxifylline, a microfilament depolymerizing agent

Cancer Letters, 1996
B16 melanoma has proved to be an ideal model for investigating metastasis. The parental B16F1 line grows as a localized subcutaneous tumor in C57BL/6 or DBA/2 mice. However, by means of successive intravenous transplantation, a subline B16F10 has been established.
R P Güde
exaly   +3 more sources

Galangin inhibits tumor growth and metastasis of B16F10 melanoma

Journal of Cellular Biochemistry, 2012
AbstractGalangin, an active flavonoid extracted from the root of the Alpinia officinarum Hance, showed a cytotoxic effect on several cancer cell lines in vitro. However, there is no information available concerning its antimetastatic effect. Focal adhesion kinase (FAK), a cytoplasmic tyrosine kinase, is involved in many aspects of cellular processes ...
Wenjing, Zhang, Bo, Tang, Qilai, Huang, Zichun, Hua   +3 more
openaire   +2 more sources

Chemosensitizing Effect of Saikosaponin B on B16F10 Melanoma Cells

Nutrition and Cancer, 2017
Cancer cell resistance to chemotherapy is one of the obstacles for better cancer treatment, and inflammatory signaling pathways, such as NF-κB signaling pathway, have been recognized to be involved in such chemoresistance. In this study, we aim to identify a new approach for overcoming cancer chemoresistance by using natural compounds.
Heyao, Ma, Satoru, Yokoyama, Ikuo, Saiki, Yoshihiro, Hayakawa   +3 more
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Exposure to phenols reduces melanogenesis in B16F10 cells and zebrafish

Aquatic Toxicology
Phenols, ubiquitous environmental contaminants found in water, soil, and air, pose risks to organisms even at minimal concentrations, and many are classified as hazardous pollutants. Skin pigmentation is a natural shield against ultraviolet-induced DNA damage and oxidative stress, pivotal in reducing skin cancer incidences.
Chung-Yu Lin, Chang-Yi Wu, Chia C. Wang, Che-Hsin Lee   +3 more
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Growth of B16F10 cells is enhanced in DJ-1-deficiency pancreas

Biochemical and Biophysical Research Communications, 2023
Association between cancer risk and Parkinson's disease is still debated. DJ-1, a Parkinson's disease (PD)-related gene, is encoded by PARK-7 gene and its deficiency causes early-onset PD. In our last studies, it was found that the immunosuppressive microenvironment established in DJ-1 knockout (KO) mice can enhance metastasis of melanoma cells to ...
Chia-Hung Chien, Ming-Jen Lee, Houng-Chi Liou   +2 more
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Antiproliferative and proapoptotic actions of okra pectin on B16F10 melanoma cells

Phytotherapy Research, 2010
AbstractThe proliferation and apoptosis of metastatic melanoma cells are often abnormal. We have evaluated the action of a pectic rhamnogalacturonan obtained by hot buffer extraction of okra pods (okra RG‐I) on melanoma cell growth and survival in vitro.
Vayssade, M., Sengkhamparn, N., Verhoef, R.P., Delaigue, C., Goundiam, O., Vigneron, P., Voragen, A.G.J., Schols, H.A., Nagel, M.D.   +8 more
openaire   +2 more sources