Results 51 to 60 of about 22,003 (134)
Are microglial cells the regulators of lymphocyte responses in the CNS? [PDF]
, 2015 The infiltration of immune cells in the central nervous system is a common hallmark in different neuroinflammatory conditions. Accumulating evidence indicates that resident glial cells can establish a cross-talk with infiltrated immune cells, including T-
Almolda Ardid, Beatriz +2 more
core +4 more sources
Clinical and Translational Allergy, Volume 15, Issue 12, December 2025.ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is generally characterized by tissue‐infiltrating eosinophils. Various biologic treatments, targeting the inflammation, have demonstrated efficacy in reducing nasal polyp size and symptoms.
Sharon Van Nevel +10 more
wiley +1 more source
iMetaMed, Volume 1, Issue 2, December 2025.The maternal–fetal interface demands tolerance alongside antimicrobial defense. Plastic macrophages orchestrate inflammation resolution, tissue remodeling, and angiogenesis in normal gestation; complications (miscarriage, preterm birth) feature polarization skewing and dysfunction.
Xinyue Wang +3 more
wiley +1 more source
Molecular profile of non-small cell lung cancer in northeastern Brazil
Jornal Brasileiro de PneumologiaObjective: To investigate the histological subtypes and mutational profiles of non-small cell lung cancer in Brazil, looking for correlations among histological subtypes, expression of anaplastic lymphoma kinase (ALK), EGFR mutation status, and ...
Ana Claudia da Silva Mendes de Oliveira +7 more
doaj +1 more source
MedComm, Volume 6, Issue 12, December 2025.Role of neurotransmitters in multiple pathological processes. Various neurotransmitters, including ACh, EPI, NE, 5‐HT, histamine, DA, glutamate, GABA, and neuropeptides participate in regulating key pathological events, including tumor proliferation, tumor migration, remodeling of the immune microenvironment, and the development of NDDs and ...
Gege Li +13 more
wiley +1 more source
Potentiation of therapeutic immune responses against malignancies with monoclonal antibodies [PDF]
, 2003 Immunotherapeutic monoclonal antibodies (mAbs) can be defined as those that exert their functions by tampering with immune system cell molecules, causing an enhancement of antitumor immune responses. Some of these antibodies are agonistic ligands for
Alfaro, C. (Carlos) +9 more
core
Investigating the role of the PD-1 pathway in human ovarian cancer
, 2010 Tumours have been shown to have a number of mechanisms to suppress immunosurveillance allowing them to survive and grow. One of these mechanisms involves expression of molecules which inhibit T cells such as the molecules involved in the PD-1 pathway. PD-
Maine, Christian, Maine, Christian
core +1 more source
Immunotherapy for recurrent ovarian cancer: a further piece of the puzzle or a striking strategy? [PDF]
, 2014 Introduction: Treatment of ovarian cancer has been long standardized with the inclusion of surgery and chemotherapy based on platinum and taxanes, this strategy reaching high remission rates.
BAZAN, Viviana +13 more
core +1 more source
The Concise Guide to PHARMACOLOGY 2025/26: G protein‐coupled receptors
British Journal of Pharmacology, Volume 182, Issue S1, Page S24-S151, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +206 more
wiley +1 more source
PD-L1 partially protects renal tubular epithelial cells from the attack of CD8+cytotoxic T cells [PDF]
, 2017 Background. Activated infiltrating T cells play a crucial role in nephritic inflammation via the direct interaction with proximal tubular epithelial cells (TEC). Under inflammatory conditions, major histocompatibility complex class I and II molecules are
Starke, Astrid +2 more
core